Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092310071> ?p ?o ?g. }
- W3092310071 endingPage "20" @default.
- W3092310071 startingPage "11" @default.
- W3092310071 abstract "The brain undergoes substantial maturation during adolescence, and repeated exposure to ethanol at this time has been shown to result in long-lasting behavioral and neural consequences. During the broad period of adolescence, different neuronal populations and circuits are refined between early and late adolescence, suggesting the possibility that ethanol exposure at these differing times may lead to differential outcomes. The goal of the current study was to evaluate the impact of adolescent intermittent ethanol (AIE) during early and late adolescence on the formation of goal-directed and habitual behavior in adulthood. Male and female Sprague–Dawley rats were exposed to ethanol via intragastric gavage (4.0 g/kg, 25% v/v) every other day from postnatal day (P) 25–45 or P45–65, considered early and late adolescence, respectively. In adulthood (~P70 early or ~ P90 late), rats were gradually food-restricted and began operant training on a fixed ratio 1 schedule. Rats were then transitioned onto random interval schedules and eventually underwent a sensory-specific satiation procedure as a model of reward devaluation. Few differences as a result of adolescent ethanol exposure were found during instrumental training. Following reward devaluation, rats exposed to water and ethanol during early adolescence exhibited reductions in lever pressing, suggestive of a goal-directed response pattern. In contrast, late AIE males and females demonstrated persistent responding following both devalued and non-devalued trials, findings representative of a habitual behavior pattern. The shifts from goal-directed to habitual behavior noted only following late AIE contribute to the growing literature identifying specific behavioral consequences as a result of ethanol exposure during distinct developmental periods within adolescence. More work is needed to determine whether the greater habit formation following late AIE is also associated with elevated habitual ethanol consumption." @default.
- W3092310071 created "2020-10-15" @default.
- W3092310071 creator A5039474674 @default.
- W3092310071 creator A5069656777 @default.
- W3092310071 date "2021-03-01" @default.
- W3092310071 modified "2023-10-17" @default.
- W3092310071 title "Rats exposed to intermittent ethanol during late adolescence exhibit enhanced habitual behavior following reward devaluation" @default.
- W3092310071 cites W1521571567 @default.
- W3092310071 cites W1524688107 @default.
- W3092310071 cites W1546888689 @default.
- W3092310071 cites W1807094205 @default.
- W3092310071 cites W1964952275 @default.
- W3092310071 cites W1966241122 @default.
- W3092310071 cites W1967924369 @default.
- W3092310071 cites W1969751828 @default.
- W3092310071 cites W1973601773 @default.
- W3092310071 cites W1983256628 @default.
- W3092310071 cites W1989193256 @default.
- W3092310071 cites W1992749931 @default.
- W3092310071 cites W1997054612 @default.
- W3092310071 cites W1997141979 @default.
- W3092310071 cites W1997221050 @default.
- W3092310071 cites W2006018417 @default.
- W3092310071 cites W2007129325 @default.
- W3092310071 cites W2007724444 @default.
- W3092310071 cites W2012419404 @default.
- W3092310071 cites W2026213927 @default.
- W3092310071 cites W2044305410 @default.
- W3092310071 cites W2046558233 @default.
- W3092310071 cites W2053170041 @default.
- W3092310071 cites W2059163032 @default.
- W3092310071 cites W2059383713 @default.
- W3092310071 cites W2063586313 @default.
- W3092310071 cites W2067297132 @default.
- W3092310071 cites W2076706946 @default.
- W3092310071 cites W2077375857 @default.
- W3092310071 cites W2080858858 @default.
- W3092310071 cites W2085460866 @default.
- W3092310071 cites W2096313349 @default.
- W3092310071 cites W2099917172 @default.
- W3092310071 cites W2107213733 @default.
- W3092310071 cites W2107617948 @default.
- W3092310071 cites W2112773692 @default.
- W3092310071 cites W2125082857 @default.
- W3092310071 cites W2130299724 @default.
- W3092310071 cites W2145103486 @default.
- W3092310071 cites W2152223184 @default.
- W3092310071 cites W2167489219 @default.
- W3092310071 cites W2299121461 @default.
- W3092310071 cites W2314789224 @default.
- W3092310071 cites W2317722041 @default.
- W3092310071 cites W2344328763 @default.
- W3092310071 cites W2434627633 @default.
- W3092310071 cites W2517776081 @default.
- W3092310071 cites W2565110533 @default.
- W3092310071 cites W2588840624 @default.
- W3092310071 cites W2593687696 @default.
- W3092310071 cites W2609967814 @default.
- W3092310071 cites W2619205438 @default.
- W3092310071 cites W2625759355 @default.
- W3092310071 cites W2727140952 @default.
- W3092310071 cites W2728863335 @default.
- W3092310071 cites W2744486402 @default.
- W3092310071 cites W2745332281 @default.
- W3092310071 cites W2752128106 @default.
- W3092310071 cites W2754172760 @default.
- W3092310071 cites W2756353385 @default.
- W3092310071 cites W2768847187 @default.
- W3092310071 cites W2769505547 @default.
- W3092310071 cites W2772834590 @default.
- W3092310071 cites W2780279108 @default.
- W3092310071 cites W2783508331 @default.
- W3092310071 cites W2784025655 @default.
- W3092310071 cites W2797182088 @default.
- W3092310071 cites W2799826726 @default.
- W3092310071 cites W2807142426 @default.
- W3092310071 cites W2885913526 @default.
- W3092310071 cites W2888762285 @default.
- W3092310071 cites W2890324028 @default.
- W3092310071 cites W2910703349 @default.
- W3092310071 cites W2911293024 @default.
- W3092310071 cites W2917033658 @default.
- W3092310071 cites W2943398541 @default.
- W3092310071 cites W2946376327 @default.
- W3092310071 cites W2949147321 @default.
- W3092310071 cites W2952774244 @default.
- W3092310071 cites W2960389057 @default.
- W3092310071 cites W2963066584 @default.
- W3092310071 cites W2963296606 @default.
- W3092310071 cites W2963912578 @default.
- W3092310071 cites W2965691598 @default.
- W3092310071 cites W2971929325 @default.
- W3092310071 cites W2972051038 @default.
- W3092310071 cites W2974755263 @default.
- W3092310071 cites W2978683289 @default.
- W3092310071 cites W2980344784 @default.
- W3092310071 cites W3014251454 @default.
- W3092310071 cites W3014789300 @default.