Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092330306> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W3092330306 abstract "Currently, there are limited reports available regarding the treatment and prevention of progressive age-related hearing loss. This is because age-related hearing loss is not a critical disease with direct fatalities and has several well-established countermeasures such as hearing aids and cochlear implants. This study evaluated the efficacy of Ninjinyoeito (NYT) in the treatment of age-related hearing loss. C57BL/6J mice were divided into three groups: baseline group, untreated group, and NYT-treated group, with the latter receiving NYT treatment for 2 months. The mice were fed with NYT extract mixed with 4% mouse normal chow. Hearing loss was confirmed by a reduction in intact cell density of the auditory nerve from the age of 5 to 7 months. The suppression of hearing loss with aging and decrease in the intact cell density of the auditory nerve were significant in mice fed with NYT for 2 months. NYT has been reported to improve blood flow and enhance mitochondrial activity and may exert its protective effects on spiral neurons through these mechanisms. There was no decrease in the size of the stria vascularis from the age of 5 to 7 months in C57BL/6J mice. The present model failed to reveal the effect of NYT on atrophy of the stria vascularis of the cochlear duct. In conclusion, NYT appears to have a protective effect on the auditory nerve and suppress the progression of age-related hearing loss by reducing age-related auditory nerve degeneration." @default.
- W3092330306 created "2020-10-15" @default.
- W3092330306 creator A5007985049 @default.
- W3092330306 creator A5050721270 @default.
- W3092330306 creator A5053199678 @default.
- W3092330306 creator A5080438805 @default.
- W3092330306 date "2020-10-09" @default.
- W3092330306 modified "2023-10-12" @default.
- W3092330306 title "Ninjinyoeito Has a Protective Effect on the Auditory Nerve and Suppresses the Progression of Age-Related Hearing Loss in Mice" @default.
- W3092330306 cites W159918491 @default.
- W3092330306 cites W1969826686 @default.
- W3092330306 cites W1972306222 @default.
- W3092330306 cites W1982631057 @default.
- W3092330306 cites W2002242519 @default.
- W3092330306 cites W2020975008 @default.
- W3092330306 cites W2057663429 @default.
- W3092330306 cites W2059908764 @default.
- W3092330306 cites W2064919953 @default.
- W3092330306 cites W2069269881 @default.
- W3092330306 cites W2080713395 @default.
- W3092330306 cites W2130879060 @default.
- W3092330306 cites W2139731089 @default.
- W3092330306 cites W2145211974 @default.
- W3092330306 cites W2171600170 @default.
- W3092330306 cites W2260295367 @default.
- W3092330306 cites W2311438563 @default.
- W3092330306 cites W2528557481 @default.
- W3092330306 cites W2553801530 @default.
- W3092330306 cites W2791685461 @default.
- W3092330306 cites W2915480901 @default.
- W3092330306 cites W3014353715 @default.
- W3092330306 cites W4242949542 @default.
- W3092330306 cites W4249448382 @default.
- W3092330306 doi "https://doi.org/10.3389/fnut.2020.528864" @default.
- W3092330306 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7583632" @default.
- W3092330306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33163504" @default.
- W3092330306 hasPublicationYear "2020" @default.
- W3092330306 type Work @default.
- W3092330306 sameAs 3092330306 @default.
- W3092330306 citedByCount "3" @default.
- W3092330306 countsByYear W30923303062023 @default.
- W3092330306 crossrefType "journal-article" @default.
- W3092330306 hasAuthorship W3092330306A5007985049 @default.
- W3092330306 hasAuthorship W3092330306A5050721270 @default.
- W3092330306 hasAuthorship W3092330306A5053199678 @default.
- W3092330306 hasAuthorship W3092330306A5080438805 @default.
- W3092330306 hasBestOaLocation W30923303061 @default.
- W3092330306 hasConcept C122247490 @default.
- W3092330306 hasConcept C126322002 @default.
- W3092330306 hasConcept C2776796419 @default.
- W3092330306 hasConcept C2778585322 @default.
- W3092330306 hasConcept C2779152698 @default.
- W3092330306 hasConcept C2779912225 @default.
- W3092330306 hasConcept C2780130748 @default.
- W3092330306 hasConcept C2780493683 @default.
- W3092330306 hasConcept C2781172350 @default.
- W3092330306 hasConcept C548259974 @default.
- W3092330306 hasConcept C71924100 @default.
- W3092330306 hasConceptScore W3092330306C122247490 @default.
- W3092330306 hasConceptScore W3092330306C126322002 @default.
- W3092330306 hasConceptScore W3092330306C2776796419 @default.
- W3092330306 hasConceptScore W3092330306C2778585322 @default.
- W3092330306 hasConceptScore W3092330306C2779152698 @default.
- W3092330306 hasConceptScore W3092330306C2779912225 @default.
- W3092330306 hasConceptScore W3092330306C2780130748 @default.
- W3092330306 hasConceptScore W3092330306C2780493683 @default.
- W3092330306 hasConceptScore W3092330306C2781172350 @default.
- W3092330306 hasConceptScore W3092330306C548259974 @default.
- W3092330306 hasConceptScore W3092330306C71924100 @default.
- W3092330306 hasLocation W30923303061 @default.
- W3092330306 hasLocation W30923303062 @default.
- W3092330306 hasLocation W30923303063 @default.
- W3092330306 hasOpenAccess W3092330306 @default.
- W3092330306 hasPrimaryLocation W30923303061 @default.
- W3092330306 hasRelatedWork W1977840069 @default.
- W3092330306 hasRelatedWork W1992947376 @default.
- W3092330306 hasRelatedWork W2004351969 @default.
- W3092330306 hasRelatedWork W2012095162 @default.
- W3092330306 hasRelatedWork W2102184024 @default.
- W3092330306 hasRelatedWork W2119135858 @default.
- W3092330306 hasRelatedWork W2168819411 @default.
- W3092330306 hasRelatedWork W2581473130 @default.
- W3092330306 hasRelatedWork W3149716353 @default.
- W3092330306 hasRelatedWork W3160694006 @default.
- W3092330306 hasVolume "7" @default.
- W3092330306 isParatext "false" @default.
- W3092330306 isRetracted "false" @default.
- W3092330306 magId "3092330306" @default.
- W3092330306 workType "article" @default.