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- W3092430397 abstract "Summary The use of Bayesian methods to support pharmaceutical product development has grown in recent years. In clinical statistics, the drive to provide faster access for patients to medical treatments has led to a heightened focus by industry and regulatory authorities on innovative clinical trial designs, including those that apply Bayesian methods. In nonclinical statistics, Bayesian applications have also made advances. However, they have been embraced far more slowly in the nonclinical area than in the clinical counterpart. In this article, we explore some of the reasons for this slower rate of adoption. We also present the results of a survey conducted for the purpose of understanding the current state of Bayesian application in nonclinical areas and for identifying areas of priority for the DIA/ASA‐BIOP Nonclinical Bayesian Working Group. The survey explored current usage, hurdles, perceptions, and training needs for Bayesian methods among nonclinical statisticians. Based on the survey results, a set of recommendations is provided to help guide the future advancement of Bayesian applications in nonclinical pharmaceutical statistics." @default.
- W3092430397 created "2020-10-15" @default.
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- W3092430397 date "2020-10-06" @default.
- W3092430397 modified "2023-09-27" @default.
- W3092430397 title "The current state of Bayesian methods in nonclinical pharmaceutical statistics: Survey results and recommendations from the <scp>DIA</scp> / <scp>ASA‐BIOP</scp> Nonclinical Bayesian Working Group" @default.
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- W3092430397 doi "https://doi.org/10.1002/pst.2072" @default.
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