Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092443146> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3092443146 abstract "Abstract Plasmids are mobile genetic elements that often carry accessory genes, and are vectors for horizontal transfer between bacterial genomes. The detection of plasmids in large sets of genomes is crucial to analyze their spread and quantify their role in bacteria adaptation and particularly in antibiotic resistance genes propagation. Several bioinformatics methods have been developed to detect plasmids. However, they suffer from low sensitivity ( i.e ., most plasmids remain undetected) or low precision ( i.e ., these methods identify chromosomes as plasmids), and are overall not adapted to identify plasmids in whole genomes that are not fully assembled (contigs and scaffolds). Here, we present PlasForest, a homology-based random forest classifier identifying bacterial plasmid sequences in unassembled genomes. This tool is based on the determination of homologies against a database of plasmid sequences, which allow a random forest classifier to discriminate plasmid contigs. Without knowing the taxonomical origin of the samples, PlasForest identifies contigs as plasmids or chromosomes with an accuracy of 98%. Notably, it can detect 96% of plasmid contigs over 50kb with 3.3% of false positives. PlasForest outperforms other currently available tools on test datasets by being both sensitive and precise. We implemented this tool in a user-friendly pipeline that can identify plasmids in large datasets in a reasonable amount of time." @default.
- W3092443146 created "2020-10-15" @default.
- W3092443146 creator A5011931659 @default.
- W3092443146 creator A5024965499 @default.
- W3092443146 creator A5044582052 @default.
- W3092443146 creator A5088642653 @default.
- W3092443146 date "2020-10-07" @default.
- W3092443146 modified "2023-10-16" @default.
- W3092443146 title "PlasForest: a homology-based random forest classifier for plasmid detection in genomic datasets" @default.
- W3092443146 cites W1604674059 @default.
- W3092443146 cites W1989348205 @default.
- W3092443146 cites W2014846709 @default.
- W3092443146 cites W2033024573 @default.
- W3092443146 cites W2050077513 @default.
- W3092443146 cites W2104704801 @default.
- W3092443146 cites W2114850508 @default.
- W3092443146 cites W2119902463 @default.
- W3092443146 cites W2123658138 @default.
- W3092443146 cites W2140647036 @default.
- W3092443146 cites W2143325926 @default.
- W3092443146 cites W2620760558 @default.
- W3092443146 cites W2738855940 @default.
- W3092443146 cites W2782623083 @default.
- W3092443146 cites W2977723904 @default.
- W3092443146 doi "https://doi.org/10.1101/2020.10.05.326819" @default.
- W3092443146 hasPublicationYear "2020" @default.
- W3092443146 type Work @default.
- W3092443146 sameAs 3092443146 @default.
- W3092443146 citedByCount "0" @default.
- W3092443146 crossrefType "posted-content" @default.
- W3092443146 hasAuthorship W3092443146A5011931659 @default.
- W3092443146 hasAuthorship W3092443146A5024965499 @default.
- W3092443146 hasAuthorship W3092443146A5044582052 @default.
- W3092443146 hasAuthorship W3092443146A5088642653 @default.
- W3092443146 hasBestOaLocation W30924431461 @default.
- W3092443146 hasConcept C104317684 @default.
- W3092443146 hasConcept C132533263 @default.
- W3092443146 hasConcept C141231307 @default.
- W3092443146 hasConcept C154945302 @default.
- W3092443146 hasConcept C165525559 @default.
- W3092443146 hasConcept C169258074 @default.
- W3092443146 hasConcept C22744801 @default.
- W3092443146 hasConcept C3742359 @default.
- W3092443146 hasConcept C41008148 @default.
- W3092443146 hasConcept C54355233 @default.
- W3092443146 hasConcept C59582021 @default.
- W3092443146 hasConcept C64869954 @default.
- W3092443146 hasConcept C70721500 @default.
- W3092443146 hasConcept C86803240 @default.
- W3092443146 hasConcept C92938381 @default.
- W3092443146 hasConcept C95623464 @default.
- W3092443146 hasConceptScore W3092443146C104317684 @default.
- W3092443146 hasConceptScore W3092443146C132533263 @default.
- W3092443146 hasConceptScore W3092443146C141231307 @default.
- W3092443146 hasConceptScore W3092443146C154945302 @default.
- W3092443146 hasConceptScore W3092443146C165525559 @default.
- W3092443146 hasConceptScore W3092443146C169258074 @default.
- W3092443146 hasConceptScore W3092443146C22744801 @default.
- W3092443146 hasConceptScore W3092443146C3742359 @default.
- W3092443146 hasConceptScore W3092443146C41008148 @default.
- W3092443146 hasConceptScore W3092443146C54355233 @default.
- W3092443146 hasConceptScore W3092443146C59582021 @default.
- W3092443146 hasConceptScore W3092443146C64869954 @default.
- W3092443146 hasConceptScore W3092443146C70721500 @default.
- W3092443146 hasConceptScore W3092443146C86803240 @default.
- W3092443146 hasConceptScore W3092443146C92938381 @default.
- W3092443146 hasConceptScore W3092443146C95623464 @default.
- W3092443146 hasLocation W30924431461 @default.
- W3092443146 hasLocation W30924431462 @default.
- W3092443146 hasLocation W30924431463 @default.
- W3092443146 hasLocation W30924431464 @default.
- W3092443146 hasLocation W30924431465 @default.
- W3092443146 hasLocation W30924431466 @default.
- W3092443146 hasLocation W30924431467 @default.
- W3092443146 hasOpenAccess W3092443146 @default.
- W3092443146 hasPrimaryLocation W30924431461 @default.
- W3092443146 hasRelatedWork W1571771606 @default.
- W3092443146 hasRelatedWork W2037702752 @default.
- W3092443146 hasRelatedWork W2067855625 @default.
- W3092443146 hasRelatedWork W2108332051 @default.
- W3092443146 hasRelatedWork W2154486014 @default.
- W3092443146 hasRelatedWork W2524850911 @default.
- W3092443146 hasRelatedWork W2633087218 @default.
- W3092443146 hasRelatedWork W2793602347 @default.
- W3092443146 hasRelatedWork W2944602870 @default.
- W3092443146 hasRelatedWork W3092443146 @default.
- W3092443146 isParatext "false" @default.
- W3092443146 isRetracted "false" @default.
- W3092443146 magId "3092443146" @default.
- W3092443146 workType "article" @default.