FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092543048> ?p ?o ?g. }

• W3092543048 endingPage "237" @default.
• W3092543048 startingPage "230" @default.
• W3092543048 abstract "In order to understand events and mechanisms present in the pathophysiology of tilapia's chronic inflammation and based on the immunomodulatory activity attributed to cyclophosphamide which is widely used to suppress immune responses in human medicine, the present study investigated the effects of cyclophosphamide (CYP) treatment on the modulation of foreign body inflammatory reaction in Nile tilapia (Oreochromis niloticus) with round glass coverslip implanted in the subcutaneous tissue (9 mm of diameter). Forty tilapia (151 ± 10,2 g) were randomly distributed in 5 aquariums (n = 8) with a capacity of 250 L of water each, to compose two treatments (sampled 3 and 6 days post-implantation): implanted/untreated (control) and implanted/treated with 200 mg of CYP kg−1 of b.w., through i.p. route. A fifth group (n = 8) was sampled without any stimulus (naive) to obtain reference values. CYP-treated tilapia showed decrease in macrophage accumulation, giant cell formation and Langhans cells on the glass coverslip when compared to control fish. The treatment with CYP resulted in decrease of leukocyte and thrombocyte counts. Decrease in alpha-2-macroglobulin, ceruloplasmin, albumin and transferrin levels, as well as increase in haptoglobin, complement C3 and apolipoprotein A1 were observed in tilapias during foreign body inflammation. Blood levels of complement C3, alpha-2-macroglobulin, ceruloplasmin and transferrin were modulated by treatment with CYP. Therefore, the treatment with 200 mg of CYP kg−1 of b.w. in tilapia resulted in an anti-inflammatory effect by suppressing the dynamics between leukocytes in the bloodstream and macrophage accumulation with giant cell formation in the inflamed focus, as well as by modulating APPs during foreign body reaction." @default.
• W3092543048 created "2020-10-15" @default.
• W3092543048 creator A5005386269 @default.
• W3092543048 creator A5006277842 @default.
• W3092543048 creator A5010058926 @default.
• W3092543048 creator A5018497110 @default.
• W3092543048 creator A5030468662 @default.
• W3092543048 creator A5053771248 @default.
• W3092543048 creator A5062411085 @default.
• W3092543048 creator A5069663658 @default.
• W3092543048 creator A5087550740 @default.
• W3092543048 date "2020-12-01" @default.
• W3092543048 modified "2023-10-15" @default.
• W3092543048 title "Cyclophosphamide modulated the foreign body inflammatory reaction in tilapia (Oreochromis niloticus)" @default.
• W3092543048 cites W1494557423 @default.
• W3092543048 cites W1504269001 @default.
• W3092543048 cites W1549659722 @default.
• W3092543048 cites W1977958026 @default.
• W3092543048 cites W1978802563 @default.
• W3092543048 cites W1986927121 @default.
• W3092543048 cites W1987633541 @default.
• W3092543048 cites W1992786776 @default.
• W3092543048 cites W1993155998 @default.
• W3092543048 cites W2002148098 @default.
• W3092543048 cites W2006084011 @default.
• W3092543048 cites W2011294054 @default.
• W3092543048 cites W2011964301 @default.
• W3092543048 cites W2032957831 @default.
• W3092543048 cites W2034349853 @default.
• W3092543048 cites W2034954825 @default.
• W3092543048 cites W2037988032 @default.
• W3092543048 cites W2038476184 @default.
• W3092543048 cites W2039350952 @default.
• W3092543048 cites W2043999522 @default.
• W3092543048 cites W2055619177 @default.
• W3092543048 cites W2071583157 @default.
• W3092543048 cites W2071600978 @default.
• W3092543048 cites W2073723755 @default.
• W3092543048 cites W2085181720 @default.
• W3092543048 cites W2089173182 @default.
• W3092543048 cites W2090025932 @default.
• W3092543048 cites W2095166152 @default.
• W3092543048 cites W2100837269 @default.
• W3092543048 cites W2103609755 @default.
• W3092543048 cites W2113131573 @default.
• W3092543048 cites W2125693102 @default.
• W3092543048 cites W2126269412 @default.
• W3092543048 cites W2148230487 @default.
• W3092543048 cites W2163453836 @default.
• W3092543048 cites W2164894027 @default.
• W3092543048 cites W2168957566 @default.
• W3092543048 cites W2183044194 @default.
• W3092543048 cites W2317184793 @default.
• W3092543048 cites W2560894090 @default.
• W3092543048 cites W2561674264 @default.
• W3092543048 cites W2564398130 @default.
• W3092543048 cites W2625710438 @default.
• W3092543048 cites W2736162298 @default.
• W3092543048 cites W2739801482 @default.
• W3092543048 cites W2796391990 @default.
• W3092543048 cites W2899717252 @default.
• W3092543048 cites W2914267774 @default.
• W3092543048 cites W2922315207 @default.
• W3092543048 cites W2958203318 @default.
• W3092543048 cites W2966502077 @default.
• W3092543048 cites W3013329289 @default.
• W3092543048 cites W4313360132 @default.
• W3092543048 doi "https://doi.org/10.1016/j.fsi.2020.09.039" @default.
• W3092543048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33039531" @default.
• W3092543048 hasPublicationYear "2020" @default.
• W3092543048 type Work @default.
• W3092543048 sameAs 3092543048 @default.
• W3092543048 citedByCount "4" @default.
• W3092543048 countsByYear W30925430482021 @default.
• W3092543048 countsByYear W30925430482022 @default.
• W3092543048 crossrefType "journal-article" @default.
• W3092543048 hasAuthorship W3092543048A5005386269 @default.
• W3092543048 hasAuthorship W3092543048A5006277842 @default.
• W3092543048 hasAuthorship W3092543048A5010058926 @default.
• W3092543048 hasAuthorship W3092543048A5018497110 @default.
• W3092543048 hasAuthorship W3092543048A5030468662 @default.
• W3092543048 hasAuthorship W3092543048A5053771248 @default.
• W3092543048 hasAuthorship W3092543048A5062411085 @default.
• W3092543048 hasAuthorship W3092543048A5069663658 @default.
• W3092543048 hasAuthorship W3092543048A5087550740 @default.
• W3092543048 hasConcept C126322002 @default.
• W3092543048 hasConcept C134018914 @default.
• W3092543048 hasConcept C203014093 @default.
• W3092543048 hasConcept C206396517 @default.
• W3092543048 hasConcept C22814914 @default.
• W3092543048 hasConcept C2776914184 @default.
• W3092543048 hasConcept C2778658382 @default.
• W3092543048 hasConcept C2779286987 @default.
• W3092543048 hasConcept C2780129523 @default.
• W3092543048 hasConcept C28452662 @default.
• W3092543048 hasConcept C2909208804 @default.
• W3092543048 hasConcept C505870484 @default.
• W3092543048 hasConcept C71924100 @default.

• next