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• W3092581372 endingPage "2895.e6" @default.
• W3092581372 startingPage "2878" @default.
• W3092581372 abstract "Delayed immune-mediated adverse drug reactions (IM-ADRs) are defined as reactions occurring more than 6 hours after dosing. They include heterogeneous clinical phenotypes that are typically T-cell-mediated reactions with distinct mechanisms across a wide spectrum of severity from benign exanthems through to life-threatening cutaneous or organ-specific diseases. For mild reactions such as benign exanthem, considerations for delabeling are similar to immediate reactions and may include a graded or single-dose drug challenge with or without preceding skin or patch testing. Evaluation of challenging cases such as the patient who is on multiple drugs at the time a severe delayed IM-ADR occurs should prioritize clinical ascertainment of the most likely phenotype and implicated drug(s). Although not widely available and validated, procedures such as patch testing, delayed intradermal skin testing, and laboratory-based functional drug assays or genetic (human leukocyte antigen) testing may provide valuable information to further help risk stratify patients and identify the likely implicated and/or cross-reactive drug(s). The decision to use a drug challenge as a diagnostic or delabeling tool in a patient with a severe delayed IM-ADR should weigh the risk-benefit ratio, balancing the severity and priority for the treatment of the underlying, and the availability of alternative efficacious and safe treatments." @default.
• W3092581372 created "2020-10-15" @default.
• W3092581372 creator A5009308092 @default.
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• W3092581372 creator A5038304654 @default.
• W3092581372 creator A5080985934 @default.
• W3092581372 creator A5082162351 @default.
• W3092581372 date "2020-10-01" @default.
• W3092581372 modified "2023-10-18" @default.
• W3092581372 title "Delabeling Delayed Drug Hypersensitivity: How Far Can You Safely Go?" @default.
• W3092581372 cites W1540812373 @default.
• W3092581372 cites W1542823104 @default.
• W3092581372 cites W1565231393 @default.
• W3092581372 cites W1571932204 @default.
• W3092581372 cites W1597914077 @default.
• W3092581372 cites W1752341662 @default.
• W3092581372 cites W1847283908 @default.
• W3092581372 cites W1868489165 @default.
• W3092581372 cites W1901880560 @default.
• W3092581372 cites W1906801702 @default.
• W3092581372 cites W1911617476 @default.
• W3092581372 cites W1965829032 @default.
• W3092581372 cites W1967569514 @default.
• W3092581372 cites W1969575821 @default.
• W3092581372 cites W1976143261 @default.
• W3092581372 cites W1977908749 @default.
• W3092581372 cites W1978460783 @default.
• W3092581372 cites W1991301773 @default.
• W3092581372 cites W1992703470 @default.
• W3092581372 cites W1994606543 @default.
• W3092581372 cites W1994855217 @default.
• W3092581372 cites W1995094099 @default.
• W3092581372 cites W1995941422 @default.
• W3092581372 cites W1998665927 @default.
• W3092581372 cites W1999122999 @default.
• W3092581372 cites W1999422050 @default.
• W3092581372 cites W2000014139 @default.
• W3092581372 cites W2001714524 @default.
• W3092581372 cites W2003268732 @default.
• W3092581372 cites W2003889587 @default.
• W3092581372 cites W2004772981 @default.
• W3092581372 cites W2005673189 @default.
• W3092581372 cites W2005840170 @default.
• W3092581372 cites W2007679918 @default.
• W3092581372 cites W2011477740 @default.
• W3092581372 cites W2018873282 @default.
• W3092581372 cites W2022744448 @default.
• W3092581372 cites W2024078462 @default.
• W3092581372 cites W2025160125 @default.
• W3092581372 cites W2027502449 @default.
• W3092581372 cites W2031620745 @default.
• W3092581372 cites W2037902632 @default.
• W3092581372 cites W2049902892 @default.
• W3092581372 cites W2050722104 @default.
• W3092581372 cites W2051793219 @default.
• W3092581372 cites W2052208913 @default.
• W3092581372 cites W2053107833 @default.
• W3092581372 cites W2053896303 @default.
• W3092581372 cites W2054805497 @default.
• W3092581372 cites W2056295780 @default.
• W3092581372 cites W2056811697 @default.
• W3092581372 cites W2059554755 @default.
• W3092581372 cites W2063237125 @default.
• W3092581372 cites W2064226160 @default.
• W3092581372 cites W2064697322 @default.
• W3092581372 cites W2067200344 @default.
• W3092581372 cites W2071070981 @default.
• W3092581372 cites W2072815680 @default.
• W3092581372 cites W2075422290 @default.
• W3092581372 cites W2076794414 @default.
• W3092581372 cites W2076907084 @default.
• W3092581372 cites W2083275011 @default.
• W3092581372 cites W2083508836 @default.
• W3092581372 cites W2083704008 @default.
• W3092581372 cites W2086841625 @default.
• W3092581372 cites W2092786402 @default.
• W3092581372 cites W2093042860 @default.
• W3092581372 cites W2096385219 @default.
• W3092581372 cites W2099552063 @default.
• W3092581372 cites W2100215785 @default.
• W3092581372 cites W2101686892 @default.
• W3092581372 cites W2101761365 @default.
• W3092581372 cites W2107418662 @default.
• W3092581372 cites W2109018114 @default.
• W3092581372 cites W2112182958 @default.
• W3092581372 cites W2113952844 @default.
• W3092581372 cites W2121812959 @default.
• W3092581372 cites W2124205535 @default.
• W3092581372 cites W2124366046 @default.
• W3092581372 cites W2124725652 @default.
• W3092581372 cites W2130028963 @default.
• W3092581372 cites W2131965148 @default.
• W3092581372 cites W2133714677 @default.
• W3092581372 cites W2133880152 @default.
• W3092581372 cites W2134373673 @default.
• W3092581372 cites W2140055542 @default.
• W3092581372 cites W2144959311 @default.
• W3092581372 cites W2146823343 @default.

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