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- W3092605241 abstract "Abstract Gastroparesis causes impairment in quality of life with deleterious impacts on health. Complicating our understanding of the condition is the combination of different insults which can provoke the disorder. No matter the etiology, it is likely that virtually all gastroparesis patients do suffer from perturbations in the brain-gut innervation derived from the vagus nerve and/or the enteric nervous system. While traditionally management of impaired brain-gut axis function has focused on the motor aspects of gastroparesis pathophysiology (stomach emptying), sensory elements likely contribute to patient suffering. Namely, there are patients who appear to have exaggerated symptom manifestations despite relatively mild impairment in stomach emptying time and vice versa. This chapter provides a unified framework for both motor and sensory dysfunction in the brain-gut axis as it relates to gastroparesis. Doing so provides a model that could be applied to other “functional” gastrointestinal disorders." @default.
- W3092605241 created "2020-10-15" @default.
- W3092605241 creator A5015605324 @default.
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- W3092605241 date "2021-01-01" @default.
- W3092605241 modified "2023-10-18" @default.
- W3092605241 title "Gastroparesis and the brain-gut axis" @default.
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- W3092605241 doi "https://doi.org/10.1016/b978-0-12-818586-5.00009-0" @default.
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