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• W3092630470 abstract "Purpose To report the anatomic and functional outcomes of autologous retinal transplantation (ART). Design Multicenter, retrospective, interventional, consecutive case series. Participants One hundred thirty eyes of 130 patients undergoing ART for the repair of primary and refractory macular holes (MHs), as well as combined MH-rhegmatogenous retinal detachment (MH-RRD), between January 2017 and December 2019. Methods All patients underwent pars plana vitrectomy and ART, with surgeon modification of intraoperative variables. A large array of preoperative, intraoperative, and postoperative data was collected. Two masked reviewers graded OCT images. Multivariate statistical analysis and subgroup analysis were performed. Main Outcome Measures Macular hole closure rate, visual acuity (VA), external limiting membrane and ellipsoid zone (EZ) band integrity, and alignment of neurosensory layers (ANL) on OCT. Results One hundred thirty ART surgeries were performed by 33 vitreoretinal surgeons worldwide. Patient demographics were: mean age of 63 ± 6.3 years, 58% female, 41% White, 23% Black, 19% Asian, and 17% Latino. Preoperative VA was 1.37 ± 0.12 logarithm of the minimum angle of resolution (logMAR; Snellen equivalent, approximately 20/500), which improved significantly to 1.05 ± 0.09 logMAR (Snellen equivalent, approximately 20/225; P < 0.001) after surgery (mean follow-up, 8.6 ± 0.8 months). Autologous retinal transplantation was performed for primary MH repair in 27% of patients (n = 35), for refractory MH in 58% of patients (n = 76; mean number of previous surgeries, 1.6 ± 0.2), and for MH-RRD in 15% of patients (n = 19). Mean maximum MH diameter was 1470 ± 160 μm, mean minimum diameter was 840 ± 94 μm, and mean axial length was 24.6 ± 3.2 mm. Overall, 89% of MHs closed (78.5% complete; 10% small eccentric defect), with a 95% closure rate in MH-RRD (68.4% complete; 26.3% small eccentric defect). Visual acuity improved by at least 3 lines in 43% of eyes and by at least 5 lines in 29% of eyes. Reconstitution of the EZ (P = 0.02) and ANL (P = 0.01) on OCT were associated with better final VA. Five cases of ART graft dislocation (3.8%), 5 cases of postoperative retinal detachment (3.8%), and 1 case of endophthalmitis (0.77%) occurred. Conclusions In this global experience, patients undergoing ART for large primary and refractory MHs and MH-RRDs achieved good anatomic and functional outcomes, with low complication rates despite complex surgical pathologic features. To report the anatomic and functional outcomes of autologous retinal transplantation (ART). Multicenter, retrospective, interventional, consecutive case series. One hundred thirty eyes of 130 patients undergoing ART for the repair of primary and refractory macular holes (MHs), as well as combined MH-rhegmatogenous retinal detachment (MH-RRD), between January 2017 and December 2019. All patients underwent pars plana vitrectomy and ART, with surgeon modification of intraoperative variables. A large array of preoperative, intraoperative, and postoperative data was collected. Two masked reviewers graded OCT images. Multivariate statistical analysis and subgroup analysis were performed. Macular hole closure rate, visual acuity (VA), external limiting membrane and ellipsoid zone (EZ) band integrity, and alignment of neurosensory layers (ANL) on OCT. One hundred thirty ART surgeries were performed by 33 vitreoretinal surgeons worldwide. Patient demographics were: mean age of 63 ± 6.3 years, 58% female, 41% White, 23% Black, 19% Asian, and 17% Latino. Preoperative VA was 1.37 ± 0.12 logarithm of the minimum angle of resolution (logMAR; Snellen equivalent, approximately 20/500), which improved significantly to 1.05 ± 0.09 logMAR (Snellen equivalent, approximately 20/225; P < 0.001) after surgery (mean follow-up, 8.6 ± 0.8 months). Autologous retinal transplantation was performed for primary MH repair in 27% of patients (n = 35), for refractory MH in 58% of patients (n = 76; mean number of previous surgeries, 1.6 ± 0.2), and for MH-RRD in 15% of patients (n = 19). Mean maximum MH diameter was 1470 ± 160 μm, mean minimum diameter was 840 ± 94 μm, and mean axial length was 24.6 ± 3.2 mm. Overall, 89% of MHs closed (78.5% complete; 10% small eccentric defect), with a 95% closure rate in MH-RRD (68.4% complete; 26.3% small eccentric defect). Visual acuity improved by at least 3 lines in 43% of eyes and by at least 5 lines in 29% of eyes. Reconstitution of the EZ (P = 0.02) and ANL (P = 0.01) on OCT were associated with better final VA. Five cases of ART graft dislocation (3.8%), 5 cases of postoperative retinal detachment (3.8%), and 1 case of endophthalmitis (0.77%) occurred. In this global experience, patients undergoing ART for large primary and refractory MHs and MH-RRDs achieved good anatomic and functional outcomes, with low complication rates despite complex surgical pathologic features." @default.
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• W3092630470 date "2021-05-01" @default.
• W3092630470 modified "2023-10-16" @default.
• W3092630470 title "Autologous Retinal Transplantation for Primary and Refractory Macular Holes and Macular Hole Retinal Detachments" @default.
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• W3092630470 cites W1980475219 @default.
• W3092630470 cites W1983159993 @default.
• W3092630470 cites W1995397454 @default.
• W3092630470 cites W2000711092 @default.
• W3092630470 cites W2006311478 @default.
• W3092630470 cites W2029056490 @default.
• W3092630470 cites W2048067641 @default.
• W3092630470 cites W2065262375 @default.
• W3092630470 cites W2065579328 @default.
• W3092630470 cites W2076461829 @default.
• W3092630470 cites W2082355308 @default.
• W3092630470 cites W2089280487 @default.
• W3092630470 cites W2090604135 @default.
• W3092630470 cites W2094894181 @default.
• W3092630470 cites W2099057309 @default.
• W3092630470 cites W2151250124 @default.
• W3092630470 cites W2161602638 @default.
• W3092630470 cites W2203049310 @default.
• W3092630470 cites W2316782837 @default.
• W3092630470 cites W2584962053 @default.
• W3092630470 cites W2746475873 @default.
• W3092630470 cites W2754831543 @default.
• W3092630470 cites W2770751975 @default.
• W3092630470 cites W2781267110 @default.
• W3092630470 cites W2792576979 @default.
• W3092630470 cites W2794579905 @default.
• W3092630470 cites W2889099128 @default.
• W3092630470 cites W2891356923 @default.
• W3092630470 cites W2897431885 @default.
• W3092630470 cites W2914769693 @default.
• W3092630470 cites W2930090322 @default.
• W3092630470 cites W2964018364 @default.
• W3092630470 cites W2971111924 @default.
• W3092630470 cites W2994573084 @default.
• W3092630470 cites W2995372945 @default.
• W3092630470 cites W2998698818 @default.
• W3092630470 cites W2998739622 @default.
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• W3092630470 doi "https://doi.org/10.1016/j.ophtha.2020.10.007" @default.
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