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• W3092683460 abstract "To assess the sonographic changes in JZ anatomy during IVF cycles in unexplained infertility and to observe whether sonographic findings are prognostic for IVF outcomes. Prospective cohort study. In this prospective study, patients with unexplained infertility were prospectively recruited between January 2012 and December 2012. Exclusion criteria were presence of known cause of infertility including tubal factor, endometriosis, male factor, and decreased ovarian reserve; history of irregular menses, pelvic or uterine surgery, myoma utery or adenomyosis. JZ anatomy was evaluated with serial transvaginal ultarsonographic meausurements.Transvaginal ultrasound scans of endometrium and JZ were performed on the day of initiation of ovulation induction(day 2), day 7 of ovulation induction, the day of HCG injection, and the day of oocyte retrieval. Measurements of the JZ were done as anterior,posterior and fundal dimensions in sagittal plane. At the end of the treatment, patients who conceived and who did not were compared for junctional zonal changes. A total of 56 subjects were included in the study. Twenty three pregnant women (mean age: 32,1 ± 4.1, range 25 to 38) and 33 non-pregnant women (mean age: 30, 1 ±5.0, range 24 to 38) were analysed in the final comparisons. Basic characteristics of the groups in terms of age, duration of ovulation, total dosages of gonodotropines used, number of oocytes retrieved, quality of embryo and number of embryos transferred were similar. Anterior, posterior, fundal, maximum and mean JZ diameters were meausured. Mean anterior diameter measured on the initiation day among pregnant women was significantly lower compared to non-pregnant women (3.88 ± 0.77 vs. 4.47 ± 0.96, p=0.024), JZ thickness on the initiation day was markedly lower and consistently increased during the cycle among women who achieved pregnancy. However, non-pregnant women had higher initial JZ thickness which remained almost similar thereafter. Posterior, fundal, maximum and the mean of all four JZ diameters were similar on the initiation day, Day 7, day of HCG injection and day of oocyte retrieval measurements of these for diameters were all similar in pregnant and non-pregnant women. Anterior JZ thickness at the initiation of ovulation induction has some influences on ivf outcomes in unexplained infertile patients. Randomised controlled trials including more patients are required to elucidate the complexity of the ‘enigmatic JZ’ and its potential effects on reproduction" @default.
• W3092683460 created "2020-10-22" @default.
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• W3092683460 date "2020-09-01" @default.
• W3092683460 modified "2023-09-26" @default.
• W3092683460 title "DOES JUNCTIONAL ZONE (JZ) THICKNESS EFFECT IMPLANTATION AND IN VITRO FERTILIZATION (IVF) SUCCESS RATES IN UNEXPLAINED INFERTIL PATIENTS?" @default.
• W3092683460 doi "https://doi.org/10.1016/j.fertnstert.2020.08.735" @default.
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