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- W3092809998 abstract "The formation of persister cells is one mechanism by which bacteria can survive exposure to environmental stresses. We show that Campylobacter jejuni 11168H forms persister cells at a frequency of 10-3 after exposure to 100 x MIC of penicillin G for 24 hours. Staining the cell population with a redox sensitive fluorescent dye revealed that penicillin G treatment resulted in the appearance of a population of cells with increased fluorescence. We present evidence, to show this is a consequence of over-expressed redox protein activity in, or associated with, the electron transport chain. The metabolic burst in penicillin G treated C. jejuni cells could lead to limited reactive oxygen species (ROS) formation that might play a role in persister cell formation." @default.
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- W3092809998 date "2020-10-19" @default.
- W3092809998 modified "2023-09-27" @default.
- W3092809998 title "Campylobacter jejuni 11168H Exposed to Penicillin Forms Persister Cells and Cells With Altered Redox Protein Activity" @default.
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- W3092809998 doi "https://doi.org/10.3389/fcimb.2020.565975" @default.
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