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- W3092810040 abstract "To characterize a population of women with congenital uterine anomalies (CUA) and cervical cerclage placement, and to evaluate the subsequent incidence of preterm delivery (PTD). Case Series Subjects were identified from an existing database including women with CUAs and a singleton, non-anomalous gestation with delivery from 2013-2018 at a single tertiary care center. Inclusion criteria included women with a CUA (arcuate, septate, unicornuate, bicornuate, or uterine didelphys) and placement of cervical cerclage for any indication. Women with multiple gestations and fetal anomalies were excluded. Out of 100 women in the database, seven met inclusion criteria; four bicornuate, one unicornuate, one septate, and one didelphys. Five underwent history indicated cerclage placement, one ultrasound indicated, and one exam indicated (Table). Cerclage was placed at a median gestational age of 14w0d (range: 12w0d to 19w2d). Three women experienced a previable delivery with stillbirth or neonatal demise at a median gestational age of 21w1d. Among those delivering beyond viability, the median gestational age at delivery was 32w4d. Of women with history indicated cerclage, 3 of 5 delivered viable infants, as did the patient with the ultrasound indicated cerclage. Delivery complications included chorioamnionitis (n=1) and placental abruption (n=1). No cases of postpartum hemorrhage, endometritis, or need for maternal admission to the intensive care unit were noted. The median birth weight of the four living infants was 1888g (range: 1320 to 2385g) with a median hospital length of stay of 26 days (range: 2-56). One infant suffered from retinopathy of prematurity, while no neonates had intraventricular hemorrhage, neonatal sepsis, or necrotizing enterocolitis. There is limited data available regarding the utility of cerclage placement in women with CUAs to prevent PTD. However, in this small case series, more than half of women experienced birth of a viable neonate who survived to hospital discharge following cerclage placement. Further research is needed to support the benefit of cerclage in women with CUAs.Tabled 1CUA TypeCerclage IndicationGA at Prior PTDGA at CerclageShort CervixGA at DeliveryBirth Weight (g)Neonatal Outcome#1BicornuateHistory24w0d18w0dNo22w5d400Neonatal Demise#2BicornuateHistory18w3d14w0dNo29w3d1320Living#3BicornuateHistory24w0d12w0dNo37w1d2385Living#4BicornuateExam-indicatedN/A18w0dYes19w4d260Stillbirth#5UnicornuateHistory22w5d12w2dNo34w3d2375Living#6SeptateHistory16w1d13w2dYes20w0dUnknownStillbirth#7DidelphysUltrasound25w0d19w2dYes30w5d1400Living Open table in a new tab" @default.
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- W3092810040 date "2020-09-01" @default.
- W3092810040 modified "2023-09-30" @default.
- W3092810040 title "CERVICAL CERCLAGE FOR PREVENTION OF PRETERM DELIVERY IN WOMEN WITH CONGENITAL UTERINE ANOMALIES: A CASE SERIES" @default.
- W3092810040 doi "https://doi.org/10.1016/j.fertnstert.2020.08.1367" @default.
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