Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092955303> ?p ?o ?g. }
- W3092955303 endingPage "2031" @default.
- W3092955303 startingPage "2013" @default.
- W3092955303 abstract "Abstract Optimal experimental designs are often formal and specific, and not intuitively plausible to practical experimenters. However, even in theory, there often are many different possible design points providing identical or nearly identical information compared to the design points of a strictly optimal design. In practical applications, this can be used to find designs that are a compromise between mathematical optimality and practical requirements, including preferences of experimenters. For this purpose, we propose a derivative‐based two‐dimensional graphical representation of the design space that, given any optimal design is already known, will show which areas of the design space are relevant for good designs and how these areas relate to each other. While existing equivalence theorems already allow such an illustration in regard to the relevance of design points only, our approach also shows whether different design points contribute the same kind of information, and thus allows tweaking of designs for practical applications, especially in regard to the splitting and combining of design points. We demonstrate the approach on a toxicological trial where a ‐optimal design for a dose–response experiment modeled by a four‐parameter log‐logistic function was requested. As these designs require a prior estimate of the relevant parameters, which is difficult to obtain in a practical situation, we also discuss an adaption of our representations to the criterion of Bayesian ‐optimality. While we focus on ‐optimality, the approach is in principle applicable to different optimality criteria as well. However, much of the computational and graphical simplicity will be lost." @default.
- W3092955303 created "2020-10-22" @default.
- W3092955303 creator A5050943602 @default.
- W3092955303 creator A5054004680 @default.
- W3092955303 date "2020-10-14" @default.
- W3092955303 modified "2023-09-26" @default.
- W3092955303 title "The design heatmap: A simple visualization of ‐optimality design problems" @default.
- W3092955303 cites W1965396598 @default.
- W3092955303 cites W1968867201 @default.
- W3092955303 cites W1970563730 @default.
- W3092955303 cites W1975316614 @default.
- W3092955303 cites W1989428732 @default.
- W3092955303 cites W2008045626 @default.
- W3092955303 cites W2017351261 @default.
- W3092955303 cites W2036065701 @default.
- W3092955303 cites W2051166651 @default.
- W3092955303 cites W2058247645 @default.
- W3092955303 cites W2072361960 @default.
- W3092955303 cites W2083097762 @default.
- W3092955303 cites W2092811195 @default.
- W3092955303 cites W2126439981 @default.
- W3092955303 cites W2161886188 @default.
- W3092955303 cites W2797638056 @default.
- W3092955303 cites W2810368869 @default.
- W3092955303 cites W3105687256 @default.
- W3092955303 cites W4233536583 @default.
- W3092955303 cites W4300031234 @default.
- W3092955303 doi "https://doi.org/10.1002/bimj.202000087" @default.
- W3092955303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33058202" @default.
- W3092955303 hasPublicationYear "2020" @default.
- W3092955303 type Work @default.
- W3092955303 sameAs 3092955303 @default.
- W3092955303 citedByCount "1" @default.
- W3092955303 countsByYear W30929553032021 @default.
- W3092955303 crossrefType "journal-article" @default.
- W3092955303 hasAuthorship W3092955303A5050943602 @default.
- W3092955303 hasAuthorship W3092955303A5054004680 @default.
- W3092955303 hasBestOaLocation W30929553031 @default.
- W3092955303 hasConcept C105795698 @default.
- W3092955303 hasConcept C111472728 @default.
- W3092955303 hasConcept C111919701 @default.
- W3092955303 hasConcept C118615104 @default.
- W3092955303 hasConcept C119857082 @default.
- W3092955303 hasConcept C120665830 @default.
- W3092955303 hasConcept C121332964 @default.
- W3092955303 hasConcept C126255220 @default.
- W3092955303 hasConcept C138885662 @default.
- W3092955303 hasConcept C17744445 @default.
- W3092955303 hasConcept C186394612 @default.
- W3092955303 hasConcept C192209626 @default.
- W3092955303 hasConcept C199539241 @default.
- W3092955303 hasConcept C2776359362 @default.
- W3092955303 hasConcept C2780069185 @default.
- W3092955303 hasConcept C2780200862 @default.
- W3092955303 hasConcept C2780586882 @default.
- W3092955303 hasConcept C29406490 @default.
- W3092955303 hasConcept C33923547 @default.
- W3092955303 hasConcept C34559072 @default.
- W3092955303 hasConcept C41008148 @default.
- W3092955303 hasConcept C94625758 @default.
- W3092955303 hasConceptScore W3092955303C105795698 @default.
- W3092955303 hasConceptScore W3092955303C111472728 @default.
- W3092955303 hasConceptScore W3092955303C111919701 @default.
- W3092955303 hasConceptScore W3092955303C118615104 @default.
- W3092955303 hasConceptScore W3092955303C119857082 @default.
- W3092955303 hasConceptScore W3092955303C120665830 @default.
- W3092955303 hasConceptScore W3092955303C121332964 @default.
- W3092955303 hasConceptScore W3092955303C126255220 @default.
- W3092955303 hasConceptScore W3092955303C138885662 @default.
- W3092955303 hasConceptScore W3092955303C17744445 @default.
- W3092955303 hasConceptScore W3092955303C186394612 @default.
- W3092955303 hasConceptScore W3092955303C192209626 @default.
- W3092955303 hasConceptScore W3092955303C199539241 @default.
- W3092955303 hasConceptScore W3092955303C2776359362 @default.
- W3092955303 hasConceptScore W3092955303C2780069185 @default.
- W3092955303 hasConceptScore W3092955303C2780200862 @default.
- W3092955303 hasConceptScore W3092955303C2780586882 @default.
- W3092955303 hasConceptScore W3092955303C29406490 @default.
- W3092955303 hasConceptScore W3092955303C33923547 @default.
- W3092955303 hasConceptScore W3092955303C34559072 @default.
- W3092955303 hasConceptScore W3092955303C41008148 @default.
- W3092955303 hasConceptScore W3092955303C94625758 @default.
- W3092955303 hasIssue "8" @default.
- W3092955303 hasLocation W30929553031 @default.
- W3092955303 hasLocation W30929553032 @default.
- W3092955303 hasOpenAccess W3092955303 @default.
- W3092955303 hasPrimaryLocation W30929553031 @default.
- W3092955303 hasRelatedWork W2001176540 @default.
- W3092955303 hasRelatedWork W2043073266 @default.
- W3092955303 hasRelatedWork W2082729972 @default.
- W3092955303 hasRelatedWork W2146888637 @default.
- W3092955303 hasRelatedWork W2171238253 @default.
- W3092955303 hasRelatedWork W3092955303 @default.
- W3092955303 hasRelatedWork W3195082120 @default.
- W3092955303 hasRelatedWork W4221014653 @default.
- W3092955303 hasRelatedWork W4293169834 @default.
- W3092955303 hasRelatedWork W4295808637 @default.
- W3092955303 hasVolume "62" @default.