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• W3093010981 abstract "SESSION TITLE: New Developments in the Diagnosis and Management of Mycobacterial and Bacterial Chest Infections SESSION TYPE: Original Investigations PRESENTED ON: October 18-21, 2020 PURPOSE: There is significant difference in the epidemiologic factors and pathophysiologic mechanisms between the major types of Diabetes mellitus (DM). The extent these impact outcomes is still being studied in various populations. The purpose of this study is to determine if diabetic patients admitted with bacterial pneumonia had difference in outcomes based on Type 1 vs Type 2 DM. METHODS: Data were extracted from the Nationwide Inpatient Sample (NIS) Database for 2016 and 2017. The numbers in the database are weighted to optimize national estimates. Hospitalizations involving adults with a principal diagnosis of bacterial pneumonia and a secondary diagnosis of DM were included. This group was further categorized based on DM type 1 vs 2. The primary outcome was inpatient mortality and secondary outcomes were Length of stay (LOS) and Total hospital Charge (THC). Multivariate regression analysis was used to adjust for possible confounders. RESULTS: There were about 383,760 adult hospitalizations principally for bacterial pneumonia, who also had DM, of which 2.2% had DM type 1. Those with DM type 1 were significantly younger on average (52.7 vs 70.4 years) but without sex variation, compared to those with DM type 2. A total of 9010 inpatient mortality (2.34%) occurred in hospitalizations for bacterial pneumonia among DM patients. After adjusting for age, sex, disease severity and race, the odds ratio (aOR) for mortality in patients with Type 2 compared with Type 1 was 0.86 (95% CI: 0 .581 - 1.282, p= 0.466). Type 2 patients had a mean increase in total hospital charge of $2370 (95% CI: 63 - 4678, p=0.044) and adjusted decrease in length of hospitalization of 0.1 days (95% CI: -0.3 - 0.2, p=0.616). CONCLUSIONS: In diabetic patients hospitalized with a principal diagnosis of bacterial pneumonia, there was no significant difference in mortality and LOS among patients with Type 2 compared to Type 1 DM, despite the known difference in the epidemiology, especially regarding age and presence of complications related to DM. CLINICAL IMPLICATIONS: Type of diabetes mellitus should not be seen as a strong confounding factor in diabetic patients admitted for bacterial pneumonia. DISCLOSURES: No relevant relationships by Ehizogie Edigin, source=Web Response No relevant relationships by Sairam Raghavan, source=Web Response No relevant relationships by Hafeez Shaka, source=Web Response" @default.
• W3093010981 created "2020-10-22" @default.
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• W3093010981 date "2020-10-01" @default.
• W3093010981 modified "2023-09-25" @default.
• W3093010981 title "PATIENTS WITH TYPE 1 DIABETES MELLITUS DO NOT HAVE WORSE OUTCOMES COMPARED TO TYPE 2 FOLLOWING ADMISSION FOR BACTERIAL PNEUMONIA" @default.
• W3093010981 doi "https://doi.org/10.1016/j.chest.2020.08.305" @default.
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