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- W3093039622 abstract "To compare the cost of hospital care for children to age 4 among ART-treated, subfertile, and fertile women. Retrospective evaluation of linked ART, birth certificate, and hospital data in Massachusetts. Cost of hospital care through age 4 was evaluated for singleton children born in Massachusetts between July 1, 2004 and December 31, 2012 to women ≥ 18 years of age with private insurance at delivery, born at ≥ 23 weeks gestational age (GA) who survived birth hospitalization to age 4. Data were obtained by linking ART deliveries from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) to the Pregnancy to Early Life Longitudinal (PELL) data system, which links birth certificates to hospital discharge records for mothers and infants in Massachusetts. We included hospitalizations, observational stays, and emergency room visits of children born to mothers of fertile (those without ART, other infertility treatments, or indicators of infertility), unassisted subfertile (UF: those without ART who had indicators of infertility and did not require any assistance with reproduction), non-ART medically assisted reproduction (MAR, required non-ART assistance with reproduction) and ART (deliveries linked to SART CORS). Costs prior to first discharge home from the birth hospitalization have been previously reported and were excluded. Outliers, or costs that were below the 1st or above the 99th percentile were recoded to 1st and 99th percentile, respectively. Multivariable gamma regression models comparing the ART, subfertile, and fertile groups were adjusted for age, race, education, chronic diabetes and hypertension, gestational diabetes and hypertension, low birthweight, prematurity, parity, gender, year of birth, and method of delivery. Costs are expressed in 2017 US Dollars. Statistical significance was noted where P<0.05. There were 158,506 fertile, 3,168 UF, 1,912 MAR, and 6,667 ART children. Adjusted least square mean costs of care (± SE) without recoding top values were $4,259 (±356), $4,894 (±428), $4,448 (±400), 4,005 (±341) respectively with only the unassisted subfertile group higher than the fertile (P<0.01) and the ART significantly lower than fertile (P=0.0012). When the 99th percentile was recoded, the adjusted costs were $4,176 (±337), $4,309 (±364), $4,666 (±406), $4,187 (±345) respectively with the MAR group having higher costs than the fertile group (P=0.0007). When selecting only those children born at <37 weeks GA only the MAR ($6,799) group had higher average cost than the fertile group ($6,116) (P=0.0027). ART-treatment had minimal effect on cost of hospital care in children to age 4. Costs were increased slightly for children born to subfertile women." @default.
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- W3093039622 date "2020-09-01" @default.
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- W3093039622 title "ART TREATMENT HAS MINIMAL EFFECT ON COST OF HOSPITAL CARE IN CHILDREN TO AGE 4" @default.
- W3093039622 doi "https://doi.org/10.1016/j.fertnstert.2020.08.325" @default.
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