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• W3093054910 endingPage "110327" @default.
• W3093054910 startingPage "110327" @default.
• W3093054910 abstract "Background: Evidence suggests that air pollution is associated with many adverse health outcomes such as cardiovascular diseases (CVD), respiratory diseases, cancer, and birth defects. Yet few studies dig into the relationship between air pollution and airborne infectious diseases. Methods: Daily data on influenza incidence were obtained from Hubei Provincial Center for Disease Control and Prevention (Hubei CDC). Data on air pollutants including nitrogen dioxide (NO2), sulfur dioxide (SO2), ground-level ozone (O3), particulate matter (PM) with aerodynamic diameter ≤ 2.5 μm (PM2.5), and PM with aerodynamic diameter ≤ 10 μm (PM10) were retrieved from ten national air sampling stations located at Wuhan. We applied generalized additive model (GAM) to estimate the associations between air pollution and the risk of influenza in Wuhan, China during 2015–2017. Results: In the single-day lag model, the largest effect estimates were observed at lag 0. An increased relative risk (RR) of influenza was significantly associated with a 10 μg/m3 increase in SO2 (RR: 1.099; 95% confidence interval [CI]: 1.011–1.195), NO2 (RR: 1.039; 95% CI: 1.013–1.065), and O3 (RR: 1.005; 95% CI: 0.994–1.016), respectively. In the multi-day lag model, concentrations of SO2, NO2, and O3 were statistically significantly associated with the risk of influenza at lag 0–1. The seasonal analysis suggests that the influence of air pollution on influenza is greater in the cold season as compared in the warm season in the early lag days. The multi-pollutant model indicates that NO2 may be a potential confounder for co-pollutants. Conclusions: Our study shows that air pollution may be associated with the risk of influenza in a broad sense. Therefore, when formulating policies to deal with influenza outbreaks in the future, factors regarding air pollution should be taken into consideration." @default.
• W3093054910 created "2020-10-22" @default.
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• W3093054910 date "2021-01-01" @default.
• W3093054910 modified "2023-10-14" @default.
• W3093054910 title "Short-term effects of ambient air pollution on the incidence of influenza in Wuhan, China: A time-series analysis" @default.
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• W3093054910 doi "https://doi.org/10.1016/j.envres.2020.110327" @default.
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