Matches in SemOpenAlex for { <https://semopenalex.org/work/W3093318914> ?p ?o ?g. }
- W3093318914 endingPage "1208" @default.
- W3093318914 startingPage "1208" @default.
- W3093318914 abstract "We previously demonstrated galactagogue effect of fenugreek in a rat model of lactation challenge, foreshadowing its use in women’s breastfeeding management. To assess longitudinal molecular mechanisms involved in milk synthesis/secretion in dams submitted to fenugreek supplementation, inguinal mammary, pituitary glands and plasma were isolated in forty-three rats nursing large 12 pups-litters and assigned to either a control (CTL) or a fenugreek-supplemented (FEN) diet during lactation. RT-PCR were performed at days 12 and 18 of lactation (L12 and L18) and the first day of involution (Inv1) to measure the relative expression of genes related to both milk synthesis and its regulation in the mammary gland and lactogenic hormones in the pituitary gland. Plasma hormone concentrations were measured by ELISA. FEN diet induced 2- to 3-times higher fold change in relative expression of several genes related to macronutrient synthesis (Fasn, Acaca, Fabp3, B4galt1, Lalba and Csn2) and energy metabolism (Cpt1a, Acads) and in IGF-1 receptor in mammary gland, mainly at L12. Pituitary oxytocin expression and plasma insulin concentration (+77.1%) were also significantly increased. Altogether, these findings suggest fenugreek might extend duration of peak milk synthesis through modulation of the insulin/GH/IGF-1 axis and increase milk ejection by activation of oxytocin secretion." @default.
- W3093318914 created "2020-10-22" @default.
- W3093318914 creator A5006066071 @default.
- W3093318914 creator A5010719773 @default.
- W3093318914 creator A5016271900 @default.
- W3093318914 creator A5016482660 @default.
- W3093318914 creator A5029012206 @default.
- W3093318914 creator A5061310332 @default.
- W3093318914 creator A5085353376 @default.
- W3093318914 date "2020-10-16" @default.
- W3093318914 modified "2023-10-18" @default.
- W3093318914 title "Fenugreek Stimulates the Expression of Genes Involved in Milk Synthesis and Milk Flow through Modulation of Insulin/GH/IGF-1 Axis and Oxytocin Secretion" @default.
- W3093318914 cites W1531975605 @default.
- W3093318914 cites W1967150811 @default.
- W3093318914 cites W1968013406 @default.
- W3093318914 cites W1973153740 @default.
- W3093318914 cites W1974756527 @default.
- W3093318914 cites W1976146903 @default.
- W3093318914 cites W1982084542 @default.
- W3093318914 cites W1993609019 @default.
- W3093318914 cites W1995528520 @default.
- W3093318914 cites W1997495703 @default.
- W3093318914 cites W2001708910 @default.
- W3093318914 cites W2003127952 @default.
- W3093318914 cites W2010225050 @default.
- W3093318914 cites W2013662496 @default.
- W3093318914 cites W2021520400 @default.
- W3093318914 cites W2026133107 @default.
- W3093318914 cites W202864358 @default.
- W3093318914 cites W2033322443 @default.
- W3093318914 cites W2035044557 @default.
- W3093318914 cites W2035360185 @default.
- W3093318914 cites W2038540481 @default.
- W3093318914 cites W2039891842 @default.
- W3093318914 cites W2043151422 @default.
- W3093318914 cites W2049009717 @default.
- W3093318914 cites W2049930287 @default.
- W3093318914 cites W2053823734 @default.
- W3093318914 cites W2062499969 @default.
- W3093318914 cites W2065333091 @default.
- W3093318914 cites W2076048868 @default.
- W3093318914 cites W2084184770 @default.
- W3093318914 cites W2092768395 @default.
- W3093318914 cites W2094051367 @default.
- W3093318914 cites W2097952652 @default.
- W3093318914 cites W2097956065 @default.
- W3093318914 cites W2102531851 @default.
- W3093318914 cites W2114872517 @default.
- W3093318914 cites W2123938699 @default.
- W3093318914 cites W2124988143 @default.
- W3093318914 cites W2128862717 @default.
- W3093318914 cites W2133651811 @default.
- W3093318914 cites W2139125449 @default.
- W3093318914 cites W2144365841 @default.
- W3093318914 cites W2151321367 @default.
- W3093318914 cites W2157782582 @default.
- W3093318914 cites W2158433107 @default.
- W3093318914 cites W2159425655 @default.
- W3093318914 cites W2161886307 @default.
- W3093318914 cites W2165178639 @default.
- W3093318914 cites W2166992789 @default.
- W3093318914 cites W2232504117 @default.
- W3093318914 cites W2246898682 @default.
- W3093318914 cites W2267159071 @default.
- W3093318914 cites W2278769514 @default.
- W3093318914 cites W2327754435 @default.
- W3093318914 cites W2405487479 @default.
- W3093318914 cites W2480915566 @default.
- W3093318914 cites W2727858022 @default.
- W3093318914 cites W2735408804 @default.
- W3093318914 cites W2766666433 @default.
- W3093318914 cites W2792868678 @default.
- W3093318914 cites W2885581785 @default.
- W3093318914 cites W2892196449 @default.
- W3093318914 cites W2900555668 @default.
- W3093318914 cites W2940796663 @default.
- W3093318914 cites W2974313337 @default.
- W3093318914 cites W2977144748 @default.
- W3093318914 cites W2981883881 @default.
- W3093318914 cites W2991372538 @default.
- W3093318914 cites W3024893802 @default.
- W3093318914 cites W4212888212 @default.
- W3093318914 cites W4229696116 @default.
- W3093318914 doi "https://doi.org/10.3390/genes11101208" @default.
- W3093318914 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7602737" @default.
- W3093318914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33081164" @default.
- W3093318914 hasPublicationYear "2020" @default.
- W3093318914 type Work @default.
- W3093318914 sameAs 3093318914 @default.
- W3093318914 citedByCount "10" @default.
- W3093318914 countsByYear W30933189142021 @default.
- W3093318914 countsByYear W30933189142022 @default.
- W3093318914 countsByYear W30933189142023 @default.
- W3093318914 crossrefType "journal-article" @default.
- W3093318914 hasAuthorship W3093318914A5006066071 @default.
- W3093318914 hasAuthorship W3093318914A5010719773 @default.
- W3093318914 hasAuthorship W3093318914A5016271900 @default.
- W3093318914 hasAuthorship W3093318914A5016482660 @default.