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- W309342259 abstract "Publisher Summary This chapter discusses peripheral modulation of hypothalamic neurons involved in drinking and eating. The lateral preoptic area (LPA) and lateral hypothalamus (LH) are involved in the neural control of ingestion. Both the LPA and LH contain cells that are affected by changes in the internal milieu and severe deficits in ingestion occur following their destruction. Activity of cells in the LPA–LH is highly correlated with peripheral stimulation associated with the changes in drinking. Neurons in the LPA–LH are particularly sensitive to gastric water infusion and distension within a time period during which changes in drinking would normally occur. Also, neurons in this region are also affected by electrical stimulation of the cervical vagus nerve, which might be related to normal gastrointestinal afferent activation. The sensory inputs to the LPA–LH motor control system, which is involved in eating and drinking and the maintenance of schedule induced polydipsia, are only partially destroyed by mid-LH lesions and the more posterior lesions produce a more complete peripheral afferent input destruction and result in more drastic effects." @default.
- W309342259 created "2016-06-24" @default.
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- W309342259 date "1981-01-01" @default.
- W309342259 modified "2023-09-27" @default.
- W309342259 title "PERIPHERAL MODULATION OF HYPOTHALAMIC NEURONS INVOLVED IN DRINKING AND EATING" @default.
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- W309342259 doi "https://doi.org/10.1016/b978-0-08-027338-9.50058-x" @default.
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