Matches in SemOpenAlex for { <https://semopenalex.org/work/W3093451213> ?p ?o ?g. }
- W3093451213 endingPage "120453" @default.
- W3093451213 startingPage "120453" @default.
- W3093451213 abstract "Thiol capped gold nanoparticles with small size, high dispersity, and broad light absorption covering ultraviolet (UV) to near infrared (NIR) region have been developed for catalysis, fluorescence imaging and photodynamic therapy (PDT). The constitution of the metal core in such nanoparticles can strongly influence the luminescence, catalysis, and stability properties. However, to date, a corresponding investigation of the influence of the metallic core on the generation of reaction oxygen species (ROS) and its therapeutic efficiency towards tumor cells remains to be lacking. Herein, we fabricated bimetallic nanoparticles by introducing bismuth into captopril capped gold nanoparticles. Surprisingly, the introduction of the Bi was found enhance the photothermal effect of the nanoparticles to a great extent, and the variation trends for the thermal effect, ROS generation rate, and tumor cell inhibition effect were found to disparate with the changes in the Au and Bi composition. The origin of the photothermal effect was deduced through density functional theory calculations based on microscopic construction. Combined with the intrinsic photodynamic effect, the bimetallic nanoparticles showed an outstanding tumor cell inhibition effect. Furthermore, due to the excellent CT imaging property, our designed nanoparticles provide the exciting possibility to realize CT imaging guided and light-mediated tumor therapy." @default.
- W3093451213 created "2020-10-22" @default.
- W3093451213 creator A5010314867 @default.
- W3093451213 creator A5029548952 @default.
- W3093451213 creator A5046349034 @default.
- W3093451213 creator A5047850752 @default.
- W3093451213 creator A5059389033 @default.
- W3093451213 creator A5062571272 @default.
- W3093451213 creator A5068723280 @default.
- W3093451213 creator A5072097629 @default.
- W3093451213 creator A5073327323 @default.
- W3093451213 creator A5073722575 @default.
- W3093451213 date "2021-01-01" @default.
- W3093451213 modified "2023-10-18" @default.
- W3093451213 title "Construction of thiol-capped ultrasmall Au–Bi bimetallic nanoparticles for X-ray CT imaging and enhanced antitumor therapy efficiency" @default.
- W3093451213 cites W1649396123 @default.
- W3093451213 cites W1866831430 @default.
- W3093451213 cites W1973426094 @default.
- W3093451213 cites W1988962727 @default.
- W3093451213 cites W1994023367 @default.
- W3093451213 cites W2001207547 @default.
- W3093451213 cites W2025638355 @default.
- W3093451213 cites W2062486688 @default.
- W3093451213 cites W2102073707 @default.
- W3093451213 cites W2118898790 @default.
- W3093451213 cites W2141686621 @default.
- W3093451213 cites W2208750608 @default.
- W3093451213 cites W2261545566 @default.
- W3093451213 cites W2332455332 @default.
- W3093451213 cites W2343828707 @default.
- W3093451213 cites W2417408922 @default.
- W3093451213 cites W2518571332 @default.
- W3093451213 cites W2535775415 @default.
- W3093451213 cites W2557424030 @default.
- W3093451213 cites W2601326448 @default.
- W3093451213 cites W2603827936 @default.
- W3093451213 cites W2604901305 @default.
- W3093451213 cites W2623531162 @default.
- W3093451213 cites W2626673123 @default.
- W3093451213 cites W2733756061 @default.
- W3093451213 cites W2737240291 @default.
- W3093451213 cites W2758327898 @default.
- W3093451213 cites W2760813780 @default.
- W3093451213 cites W2762357229 @default.
- W3093451213 cites W2767010176 @default.
- W3093451213 cites W2777876947 @default.
- W3093451213 cites W2783898088 @default.
- W3093451213 cites W2786351716 @default.
- W3093451213 cites W2786682106 @default.
- W3093451213 cites W2787300529 @default.
- W3093451213 cites W2789293316 @default.
- W3093451213 cites W2790296339 @default.
- W3093451213 cites W2791143441 @default.
- W3093451213 cites W2799562744 @default.
- W3093451213 cites W2799741896 @default.
- W3093451213 cites W2800971234 @default.
- W3093451213 cites W2802023489 @default.
- W3093451213 cites W2802282040 @default.
- W3093451213 cites W2804377836 @default.
- W3093451213 cites W2804902439 @default.
- W3093451213 cites W2808632617 @default.
- W3093451213 cites W2809867121 @default.
- W3093451213 cites W2810059192 @default.
- W3093451213 cites W2883916923 @default.
- W3093451213 cites W2885437181 @default.
- W3093451213 cites W2886103182 @default.
- W3093451213 cites W2889695769 @default.
- W3093451213 cites W2890343176 @default.
- W3093451213 cites W2890715270 @default.
- W3093451213 cites W2891218377 @default.
- W3093451213 cites W2910512142 @default.
- W3093451213 cites W2913056751 @default.
- W3093451213 cites W2915392496 @default.
- W3093451213 cites W2916762679 @default.
- W3093451213 cites W2936513263 @default.
- W3093451213 cites W3042460158 @default.
- W3093451213 cites W3047178991 @default.
- W3093451213 doi "https://doi.org/10.1016/j.biomaterials.2020.120453" @default.
- W3093451213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33069138" @default.
- W3093451213 hasPublicationYear "2021" @default.
- W3093451213 type Work @default.
- W3093451213 sameAs 3093451213 @default.
- W3093451213 citedByCount "37" @default.
- W3093451213 countsByYear W30934512132021 @default.
- W3093451213 countsByYear W30934512132022 @default.
- W3093451213 countsByYear W30934512132023 @default.
- W3093451213 crossrefType "journal-article" @default.
- W3093451213 hasAuthorship W3093451213A5010314867 @default.
- W3093451213 hasAuthorship W3093451213A5029548952 @default.
- W3093451213 hasAuthorship W3093451213A5046349034 @default.
- W3093451213 hasAuthorship W3093451213A5047850752 @default.
- W3093451213 hasAuthorship W3093451213A5059389033 @default.
- W3093451213 hasAuthorship W3093451213A5062571272 @default.
- W3093451213 hasAuthorship W3093451213A5068723280 @default.
- W3093451213 hasAuthorship W3093451213A5072097629 @default.
- W3093451213 hasAuthorship W3093451213A5073327323 @default.
- W3093451213 hasAuthorship W3093451213A5073722575 @default.
- W3093451213 hasConcept C11432220 @default.