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- W3093485177 abstract "Abstract SARS-CoV-2 can infiltrate the lower respiratory tract, resulting in severe respiratory failure and a high death rate. Normally, the airway and alveolar epithelium can be rapidly reconstituted by multipotent stem cells after episodes of infection. Here, we analyzed published RNA-seq datasets and demonstrated that cells of four different lung epithelial stem cell types express SARS-CoV-2 entry factors, including Ace2 . Thus, stem cells can be potentially infected by SARS-CoV-2, which may lead to defects in regeneration capacity partially accounting for the severity of SARS-CoV-2 infection and its consequences." @default.
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- W3093485177 date "2020-10-20" @default.
- W3093485177 modified "2023-09-24" @default.
- W3093485177 title "Expression of SARS-CoV-2 entry factors in lung epithelial stem cells and its potential implications for COVID-19" @default.
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- W3093485177 doi "https://doi.org/10.1038/s41598-020-74598-5" @default.
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