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- W3093671608 abstract "To date, skin substitute that can provide permanent wound closure is still autologous tissue-engineered skin using autologous skin cells as seed cells. The development of cultured epithelial autograft has experienced a long and tortuous process. Autologous tissue-engineered composite skin is closer to autologous split-thickness skin graft in terms of structure, function, and efficacy, which has become a research focus in recent years. Based on the actual status of research on tissue-engineered skin application, this paper reviewed the main research progresses and existing problems, and the prospect of research and development and clinical application of autologous tissue-engineered skin as permanent graft in order to provide a reference for the improvement and application of autologous tissue-engineered skin.迄今，能够永久性封闭创面的皮肤替代物仍是以自体皮肤细胞作为种子细胞的自体组织工程皮肤。培养的自体表皮移植物的发展经历了漫长而曲折的历程；自体组织工程复合皮肤在结构、功能与疗效上更接近自体断层皮片，成为近年来研究的热点。本文从组织工程皮肤应用研究的实际现状出发，就自体组织工程皮肤作为永久性移植物的主要研究进展、存在的主要问题、研究开发与临床应用前景进行综述，以期为自体组织工程皮肤改进及应用提供参考。." @default.
- W3093671608 created "2020-10-29" @default.
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- W3093671608 date "2020-10-20" @default.
- W3093671608 modified "2023-10-18" @default.
- W3093671608 title "[Research status and prospect on autologous tissue-engineered skin as permanent graft]." @default.
- W3093671608 doi "https://doi.org/10.3760/cma.j.cn501120-20200204-00043" @default.
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