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- W3093749891 abstract "INTRODUCTION: A small intestine bleed accounts for approximately 5-10% of all gastrointestinal (GI) bleeds. Evaluation of GI bleeding may include both esophagogastroduodenoscopy (EGD) and colonoscopy, but when inconclusive, video capsule endoscopy (VCE) should be considered. Small intestinal bleeds may be a result of inflammatory lesions, tumors, medications, and vascular anomalies including arteriovenous malformations or varices. Non-steroidal anti-inflammatory drugs (NSAIDS) commonly cause GI tract ulcers or erosions and rarely, diaphragmatic disease. In our case, we illustrate a case of GI bleeding in the setting of small bowel diaphragmatic disease, necessitating surgical intervention. CASE DESCRIPTION/METHODS: A 40 year old female with a three year history of recurrent melena presented from an outside hospital with melena, abdominal pain, and anorexia for one week duration. She also noted a 10 pound weight loss over two weeks. She denied alcohol or NSAID use. Of note, the patient had an EGD, colonoscopy, and VCE procedure 10 months prior, which were inconclusive. A workup for her chronic anemia included a bone marrow biopsy, noting absent iron stores and no signs of malignancy. Prior to her transfer, laboratory evaluation revealed a hemoglobin of 2.7 g/dL, for which she was given 6 units of pRBCs. She also underwent a repeat EGD and colonoscopy which were unremarkable. The patient was transferred to our hospital for higher level of care. A VCE was done to evaluate her GI bleeds which demonstrated a retained pill camera in her ileum with associated erosions. A CT scan was obtained which revealed two capsules in the ileum, anasarca, and concern for strictures. It was determined that the erosions caused by the retained pill camera were likely contributing to her GI bleeding and anemia. Subsequently, she underwent laparoscopy with partial small bowel resection; pathology noted very narrow strictures with fibrotic bands suggestive of diaphragm disease. Her anasarca and weight loss were attributed to malnourishment secondary to diaphragm disease. DISCUSSION: Diaphragm disease is often linked to heavy NSAID use, commonly presenting as protein loss enteropathy, anemia, GI bleeds and subacute obstruction. It is essential to ensure passage of capsules into the cecum after a VCE procedure. Clinicians should be vigilant about patients with these presentations as it may be indicative of small bowel pathology such as diaphragm disease, potentially leading to sequelae such as obstruction or retention requiring surgery.Figure 1.: Video capsule endoscopy image demonstrating retained pill camera.Figure 2.: Video capsule endoscopy image demonstrating small bowel erosions and stricture.Figure 3.: CT scan demonstrating two retained pill cameras." @default.
- W3093749891 created "2020-10-29" @default.
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- W3093749891 date "2020-10-01" @default.
- W3093749891 modified "2023-09-27" @default.
- W3093749891 title "S2798 Gastrointestinal Bleed in Setting of Small Bowel Diaphragmatic Disease" @default.
- W3093749891 doi "https://doi.org/10.14309/01.ajg.0000713240.02109.d5" @default.
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