FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3093762494> ?p ?o ?g. }

• W3093762494 abstract "Abstract The transcriptome of the endometrium early postpartum was profiled to determine if inflammatory gene expression was elevated in cows which subsequently developed uterine disease. Endometrial cytobrush samples were collected at 7 days postpartum (DPP) from 112 Holstein–Friesian dairy cows, from which 27 were retrospectively chosen for RNA-seq on the basis of disease classification [ten healthy and an additional 17 diagnosed with cytological endometritis (CYTO), or purulent vaginal discharge (PVD)] at 21 DPP. 297 genes were significantly differentially expressed between cows that remained healthy versus those that subsequently developed PVD, including IL1A and IL1B (adjusted p < 0.05). In contrast, only 3 genes were significantly differentially expressed in cows which subsequently developed CYTO. Accounting for the early physiological inflammatory status present in cows which do not develop disease enhanced the detection of differentially expressed genes associated with CYTO and further expression profiling in 51 additional cows showed upregulation of multiple immune genes, including IL1A , IL1B and TNFA . Despite the expected heterogeneity associated with natural infection, enhanced activation of the inflammatory response is likely a key contributory feature of both PVD and CYTO development. Prognostic biomarkers of uterine disease would be particularly valuable for seasonal-based dairy systems where any delay to conception undermines sustainability." @default.
• W3093762494 created "2020-10-29" @default.
• W3093762494 creator A5001048865 @default.
• W3093762494 creator A5002853430 @default.
• W3093762494 creator A5015452846 @default.
• W3093762494 creator A5054395909 @default.
• W3093762494 creator A5059938006 @default.
• W3093762494 creator A5091548602 @default.
• W3093762494 date "2020-10-26" @default.
• W3093762494 modified "2023-10-18" @default.
• W3093762494 title "Qualitative and quantitative differences in endometrial inflammatory gene expression precede the development of bovine uterine disease" @default.
• W3093762494 cites W1526963281 @default.
• W3093762494 cites W1554340035 @default.
• W3093762494 cites W1873207210 @default.
• W3093762494 cites W1927777754 @default.
• W3093762494 cites W1979242324 @default.
• W3093762494 cites W1986375719 @default.
• W3093762494 cites W1991721135 @default.
• W3093762494 cites W1992439009 @default.
• W3093762494 cites W1997668772 @default.
• W3093762494 cites W2001056367 @default.
• W3093762494 cites W2022835588 @default.
• W3093762494 cites W2036222092 @default.
• W3093762494 cites W2045120449 @default.
• W3093762494 cites W2046004620 @default.
• W3093762494 cites W2051611159 @default.
• W3093762494 cites W2052541235 @default.
• W3093762494 cites W2054531793 @default.
• W3093762494 cites W2075185675 @default.
• W3093762494 cites W2085563796 @default.
• W3093762494 cites W2087486011 @default.
• W3093762494 cites W2098151091 @default.
• W3093762494 cites W2098972828 @default.
• W3093762494 cites W2106286901 @default.
• W3093762494 cites W2107277218 @default.
• W3093762494 cites W2109696752 @default.
• W3093762494 cites W2114104545 @default.
• W3093762494 cites W2123402700 @default.
• W3093762494 cites W2123684196 @default.
• W3093762494 cites W2133785124 @default.
• W3093762494 cites W2133938655 @default.
• W3093762494 cites W2134753271 @default.
• W3093762494 cites W2138207763 @default.
• W3093762494 cites W2138579860 @default.
• W3093762494 cites W2138769023 @default.
• W3093762494 cites W2147412811 @default.
• W3093762494 cites W2159660882 @default.
• W3093762494 cites W2166442806 @default.
• W3093762494 cites W2168362891 @default.
• W3093762494 cites W2169456326 @default.
• W3093762494 cites W2170288546 @default.
• W3093762494 cites W2295746561 @default.
• W3093762494 cites W2587883401 @default.
• W3093762494 cites W2741457362 @default.
• W3093762494 cites W2753345042 @default.
• W3093762494 cites W2754555216 @default.
• W3093762494 cites W2766877925 @default.
• W3093762494 cites W2886441534 @default.
• W3093762494 cites W2894525817 @default.
• W3093762494 cites W2903503782 @default.
• W3093762494 cites W2950768033 @default.
• W3093762494 cites W2953033333 @default.
• W3093762494 cites W2965188195 @default.
• W3093762494 cites W2976196850 @default.
• W3093762494 cites W2984197553 @default.
• W3093762494 cites W2990912888 @default.
• W3093762494 cites W3027109485 @default.
• W3093762494 doi "https://doi.org/10.1038/s41598-020-75104-7" @default.
• W3093762494 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7588428" @default.
• W3093762494 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33106520" @default.
• W3093762494 hasPublicationYear "2020" @default.
• W3093762494 type Work @default.
• W3093762494 sameAs 3093762494 @default.
• W3093762494 citedByCount "9" @default.
• W3093762494 countsByYear W30937624942021 @default.
• W3093762494 countsByYear W30937624942022 @default.
• W3093762494 countsByYear W30937624942023 @default.
• W3093762494 crossrefType "journal-article" @default.
• W3093762494 hasAuthorship W3093762494A5001048865 @default.
• W3093762494 hasAuthorship W3093762494A5002853430 @default.
• W3093762494 hasAuthorship W3093762494A5015452846 @default.
• W3093762494 hasAuthorship W3093762494A5054395909 @default.
• W3093762494 hasAuthorship W3093762494A5059938006 @default.
• W3093762494 hasAuthorship W3093762494A5091548602 @default.
• W3093762494 hasBestOaLocation W30937624941 @default.
• W3093762494 hasConcept C104317684 @default.
• W3093762494 hasConcept C126322002 @default.
• W3093762494 hasConcept C127561419 @default.
• W3093762494 hasConcept C134018914 @default.
• W3093762494 hasConcept C150194340 @default.
• W3093762494 hasConcept C162317418 @default.
• W3093762494 hasConcept C16685009 @default.
• W3093762494 hasConcept C18431079 @default.
• W3093762494 hasConcept C203014093 @default.
• W3093762494 hasConcept C2775846227 @default.
• W3093762494 hasConcept C2776914184 @default.
• W3093762494 hasConcept C2779134260 @default.
• W3093762494 hasConcept C2779234561 @default.
• W3093762494 hasConcept C2779742232 @default.
• W3093762494 hasConcept C42407357 @default.

• next