FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3093887936> ?p ?o ?g. }

• W3093887936 endingPage "S903" @default.
• W3093887936 startingPage "S902" @default.
• W3093887936 abstract "INTRODUCTION: Primary lymphomas of the colon are rare, accounting for < 1% of all GI malignances. Studies describing the disease suggest that it most commonly involves the cecum and presents symptomatically in patients with abdominal pain and weight loss. However, given the rarity of the cancer, literature on the clinical and pathologic features of the disease are still evolving. Here, we present a case of primary follicular lymphoma affecting the sigmoid colon with a description of the corresponding colonoscopy and histologic findings. CASE DESCRIPTION/METHODS: The patient is a 71-year old female referred from her PCP for iron deficiency anemia with a hemoglobin of 11.3 g/dL and positive fecal immunochemical testing (FIT). Her symptoms included intermittent episodes of constipation for several weeks. She denied changes in stool caliber including bloody or tarry appearing stools, B-symptoms such as weight loss or night sweats, or family history of colorectal malignancy. Physical exam was unremarkable. Subsequent colonoscopy revealed an 8mm sessile polyp and 10mm semi-pedunculated polyp with a localized area of nodular mucosa in the sigmoid colon. Polyp and mucosal biopsies demonstrated atypical lymphoid infiltrate with abnormal follicular proliferation positive for CD-20, BCL-2 and BCL-6, consistent with low-grade, stage IE, follicular lymphoma. At 1-month follow-up with oncology, the patient remained asymptomatic after polypectomy and chose conservative management with active surveillance. DISCUSSION: Primary lymphoma of the colon is rare, accounting for less than 0.2% of all GI malignancies. There is limited data on the clinical and pathologic features of the disease however, current studies indicate a female predominance, chief presenting symptoms of abdominal pain and weight-loss, and largely cecum involvement. Here, we present a rare case of follicular lymphoma in the sigmoid colon of a female presenting with constipation and iron deficiency anemia. Colonoscopic features included a sessile and semi-pedunculated polyp with nodular mucosa and histology showing an atypical lymphoid infiltrate positive for CD-20, BCL-2, and BCL-6. This case provides insight both into the varying clinical and pathologic characteristics of a relatively rare disease and the importance of lymphoma as part of the differential in this patient population.Figure 1.: Colonoscopy demonstrating a 10-mm Semi-pedunculated Polyp of the sigmoid.Figure 2.: Nodular Hyperplasia of the sigmoid colon.Figure 3.: Biopsy specimen with the round follicles characteristic of follicular lymphoma seen on histology (arrows)." @default.
• W3093887936 created "2020-10-29" @default.
• W3093887936 creator A5011260788 @default.
• W3093887936 creator A5046924039 @default.
• W3093887936 creator A5059077288 @default.
• W3093887936 creator A5079374050 @default.
• W3093887936 creator A5083923569 @default.
• W3093887936 date "2020-10-01" @default.
• W3093887936 modified "2023-09-25" @default.
• W3093887936 title "S1748 Primary Follicular Lymphoma of the Colon: A Rare Case in a Rare Place" @default.
• W3093887936 doi "https://doi.org/10.14309/01.ajg.0000709040.00616.a6" @default.
• W3093887936 hasPublicationYear "2020" @default.
• W3093887936 type Work @default.
• W3093887936 sameAs 3093887936 @default.
• W3093887936 citedByCount "0" @default.
• W3093887936 crossrefType "journal-article" @default.
• W3093887936 hasAuthorship W3093887936A5011260788 @default.
• W3093887936 hasAuthorship W3093887936A5046924039 @default.
• W3093887936 hasAuthorship W3093887936A5059077288 @default.
• W3093887936 hasAuthorship W3093887936A5079374050 @default.
• W3093887936 hasAuthorship W3093887936A5083923569 @default.
• W3093887936 hasBestOaLocation W30938879361 @default.
• W3093887936 hasConcept C121608353 @default.
• W3093887936 hasConcept C126322002 @default.
• W3093887936 hasConcept C142724271 @default.
• W3093887936 hasConcept C2776870353 @default.
• W3093887936 hasConcept C2777058707 @default.
• W3093887936 hasConcept C2777910003 @default.
• W3093887936 hasConcept C2778248108 @default.
• W3093887936 hasConcept C2778292851 @default.
• W3093887936 hasConcept C2778435480 @default.
• W3093887936 hasConcept C2779338263 @default.
• W3093887936 hasConcept C2779399171 @default.
• W3093887936 hasConcept C2780833581 @default.
• W3093887936 hasConcept C2780955771 @default.
• W3093887936 hasConcept C2781074409 @default.
• W3093887936 hasConcept C2781112942 @default.
• W3093887936 hasConcept C526805850 @default.
• W3093887936 hasConcept C71924100 @default.
• W3093887936 hasConcept C90924648 @default.
• W3093887936 hasConceptScore W3093887936C121608353 @default.
• W3093887936 hasConceptScore W3093887936C126322002 @default.
• W3093887936 hasConceptScore W3093887936C142724271 @default.
• W3093887936 hasConceptScore W3093887936C2776870353 @default.
• W3093887936 hasConceptScore W3093887936C2777058707 @default.
• W3093887936 hasConceptScore W3093887936C2777910003 @default.
• W3093887936 hasConceptScore W3093887936C2778248108 @default.
• W3093887936 hasConceptScore W3093887936C2778292851 @default.
• W3093887936 hasConceptScore W3093887936C2778435480 @default.
• W3093887936 hasConceptScore W3093887936C2779338263 @default.
• W3093887936 hasConceptScore W3093887936C2779399171 @default.
• W3093887936 hasConceptScore W3093887936C2780833581 @default.
• W3093887936 hasConceptScore W3093887936C2780955771 @default.
• W3093887936 hasConceptScore W3093887936C2781074409 @default.
• W3093887936 hasConceptScore W3093887936C2781112942 @default.
• W3093887936 hasConceptScore W3093887936C526805850 @default.
• W3093887936 hasConceptScore W3093887936C71924100 @default.
• W3093887936 hasConceptScore W3093887936C90924648 @default.
• W3093887936 hasIssue "1" @default.
• W3093887936 hasLocation W30938879361 @default.
• W3093887936 hasLocation W30938879362 @default.
• W3093887936 hasOpenAccess W3093887936 @default.
• W3093887936 hasPrimaryLocation W30938879361 @default.
• W3093887936 hasRelatedWork W1989918753 @default.
• W3093887936 hasRelatedWork W2044658514 @default.
• W3093887936 hasRelatedWork W2092319801 @default.
• W3093887936 hasRelatedWork W2104003322 @default.
• W3093887936 hasRelatedWork W2169589648 @default.
• W3093887936 hasRelatedWork W2235371377 @default.
• W3093887936 hasRelatedWork W2363611241 @default.
• W3093887936 hasRelatedWork W2791459494 @default.
• W3093887936 hasRelatedWork W2978262146 @default.
• W3093887936 hasRelatedWork W2979563401 @default.
• W3093887936 hasVolume "115" @default.
• W3093887936 isParatext "false" @default.
• W3093887936 isRetracted "false" @default.
• W3093887936 magId "3093887936" @default.
• W3093887936 workType "article" @default.