FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094017060> ?p ?o ?g. }

• W3094017060 abstract "Visceral leishmaniasis is the most severe form of leishmaniasis caused by Leishmania (L.) donovani complex. Drug-resistant strains have been developed as a consequence of the current chemotherapeutic interventions, which has increased the need for advanced preventive and therapeutic strategies. A2-CPA-CPB-CTE-recombinant strain of L. tarentolae, which is non-pathogenic to humans, was shown protective in live vaccine as well as its DNA vaccine counterpart in both murine and canine models.We evaluated the effectiveness of these DNA and live vaccination harboring A2-CPA-CPB-CTE in protecting hamsters against L. infantum infection using prime-boost regimens, namely DNA/DNA and Live/Live (n=9 hamsters per group). Cationic solid lipid nanoparticles (cSLN) were utilized as an adjuvant for DNA priming and electroporation for boosting DNA. At different time points post-challenge, parasite burden and body weight as well as humoral immune responses were measured.Both immunization strategies partially protect hamsters against L. infantum challenge. This protective immunity is associated with remarkable decrease in parasite load in liver and spleen of vaccinated hamsters eight weeks after challenge compared to control group.Both test groups (DNA/DNA and Live/Live) elicited high levels of IgG2 and total IgG as humoral immune responses and lower level of parasite propagation in both liver and spleen." @default.
• W3094017060 created "2020-10-29" @default.
• W3094017060 creator A5020155400 @default.
• W3094017060 creator A5029184531 @default.
• W3094017060 creator A5031452509 @default.
• W3094017060 creator A5045644761 @default.
• W3094017060 creator A5072006658 @default.
• W3094017060 creator A5078905826 @default.
• W3094017060 creator A5080484958 @default.
• W3094017060 date "2020-09-19" @default.
• W3094017060 modified "2023-09-27" @default.
• W3094017060 title "Comparison of Protective Potency of DNA and Live Vaccines Expressing A2-CPA-CPB-CTE Antigens against Visceral Leish-maniasis in Syrian Hamster as Preliminary Study" @default.
• W3094017060 cites W13013347 @default.
• W3094017060 cites W14950300 @default.
• W3094017060 cites W1579046626 @default.
• W3094017060 cites W1944128383 @default.
• W3094017060 cites W1979573371 @default.
• W3094017060 cites W1980323496 @default.
• W3094017060 cites W1987316921 @default.
• W3094017060 cites W1998728525 @default.
• W3094017060 cites W2004059985 @default.
• W3094017060 cites W2014458110 @default.
• W3094017060 cites W2020508488 @default.
• W3094017060 cites W2022333100 @default.
• W3094017060 cites W2024822461 @default.
• W3094017060 cites W2027128438 @default.
• W3094017060 cites W2043832228 @default.
• W3094017060 cites W2048042504 @default.
• W3094017060 cites W2053949022 @default.
• W3094017060 cites W2058261647 @default.
• W3094017060 cites W2064079373 @default.
• W3094017060 cites W2070308432 @default.
• W3094017060 cites W2071531515 @default.
• W3094017060 cites W2082372194 @default.
• W3094017060 cites W2082378073 @default.
• W3094017060 cites W2088873505 @default.
• W3094017060 cites W2097165543 @default.
• W3094017060 cites W2097371306 @default.
• W3094017060 cites W2109352986 @default.
• W3094017060 cites W2116717421 @default.
• W3094017060 cites W2122510929 @default.
• W3094017060 cites W2140031668 @default.
• W3094017060 cites W2140056038 @default.
• W3094017060 cites W2161018229 @default.
• W3094017060 cites W2963273733 @default.
• W3094017060 cites W3008667379 @default.
• W3094017060 cites W3021086283 @default.
• W3094017060 doi "https://doi.org/10.18502/ijpa.v15i3.4203" @default.
• W3094017060 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7548471" @default.
• W3094017060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33082803" @default.
• W3094017060 hasPublicationYear "2020" @default.
• W3094017060 type Work @default.
• W3094017060 sameAs 3094017060 @default.
• W3094017060 citedByCount "2" @default.
• W3094017060 countsByYear W30940170602022 @default.
• W3094017060 countsByYear W30940170602023 @default.
• W3094017060 crossrefType "journal-article" @default.
• W3094017060 hasAuthorship W3094017060A5020155400 @default.
• W3094017060 hasAuthorship W3094017060A5029184531 @default.
• W3094017060 hasAuthorship W3094017060A5031452509 @default.
• W3094017060 hasAuthorship W3094017060A5045644761 @default.
• W3094017060 hasAuthorship W3094017060A5072006658 @default.
• W3094017060 hasAuthorship W3094017060A5078905826 @default.
• W3094017060 hasAuthorship W3094017060A5080484958 @default.
• W3094017060 hasBestOaLocation W30940170601 @default.
• W3094017060 hasConcept C136764020 @default.
• W3094017060 hasConcept C147483822 @default.
• W3094017060 hasConcept C159047783 @default.
• W3094017060 hasConcept C167508917 @default.
• W3094017060 hasConcept C203014093 @default.
• W3094017060 hasConcept C22070199 @default.
• W3094017060 hasConcept C2776555147 @default.
• W3094017060 hasConcept C2777863537 @default.
• W3094017060 hasConcept C2778689377 @default.
• W3094017060 hasConcept C2780801004 @default.
• W3094017060 hasConcept C2780868878 @default.
• W3094017060 hasConcept C2780931953 @default.
• W3094017060 hasConcept C2781092759 @default.
• W3094017060 hasConcept C2781257258 @default.
• W3094017060 hasConcept C2781333301 @default.
• W3094017060 hasConcept C41008148 @default.
• W3094017060 hasConcept C71928629 @default.
• W3094017060 hasConcept C86803240 @default.
• W3094017060 hasConcept C8891405 @default.
• W3094017060 hasConceptScore W3094017060C136764020 @default.
• W3094017060 hasConceptScore W3094017060C147483822 @default.
• W3094017060 hasConceptScore W3094017060C159047783 @default.
• W3094017060 hasConceptScore W3094017060C167508917 @default.
• W3094017060 hasConceptScore W3094017060C203014093 @default.
• W3094017060 hasConceptScore W3094017060C22070199 @default.
• W3094017060 hasConceptScore W3094017060C2776555147 @default.
• W3094017060 hasConceptScore W3094017060C2777863537 @default.
• W3094017060 hasConceptScore W3094017060C2778689377 @default.
• W3094017060 hasConceptScore W3094017060C2780801004 @default.
• W3094017060 hasConceptScore W3094017060C2780868878 @default.
• W3094017060 hasConceptScore W3094017060C2780931953 @default.
• W3094017060 hasConceptScore W3094017060C2781092759 @default.
• W3094017060 hasConceptScore W3094017060C2781257258 @default.
• W3094017060 hasConceptScore W3094017060C2781333301 @default.
• W3094017060 hasConceptScore W3094017060C41008148 @default.

• next