Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094056769> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3094056769 abstract "Numerous transcription factor genes associated with stress response are upregulated in Saccharomyces cerevisiae grown in the presence of inhibitors that result from pretreatment processes to unlock simple sugars from biomass. To determine if overexpression of transcription factors could improve inhibitor tolerance in robust S. cerevisiae environmental isolates as has been demonstrated in S. cerevisiae haploid laboratory strains, transcription factors were overexpressed at three different expression levels in three S. cerevisiae environmental isolates. Overexpression of the YAP1 transcription factor in these isolates did not lead to increased growth rate or reduced lag in growth, and in some cases was detrimental, when grown in the presence of either lignocellulosic hydrolysates or furfural and 5-hydroxymethyl furfural individually. The expressed Yap1p localized correctly and the expression construct improved inhibitor tolerance of a laboratory strain as previously reported, indicating that lack of improvement in the environmental isolates was due to factors other than nonfunctional expression constructs or mis-folded protein. Additional stress-related transcription factors, MSN2, MSN4, HSF1, PDR1, and RPN4, were also overexpressed at three different expression levels and all failed to improve inhibitor tolerance. Transcription factor overexpression alone is unlikely to be a viable route toward increased inhibitor tolerance of robust environmental S. cerevisiae strains." @default.
- W3094056769 created "2020-10-29" @default.
- W3094056769 creator A5003179197 @default.
- W3094056769 creator A5028552755 @default.
- W3094056769 creator A5055014435 @default.
- W3094056769 creator A5089458184 @default.
- W3094056769 date "2020-10-30" @default.
- W3094056769 modified "2023-10-16" @default.
- W3094056769 title "Impact of stress‐response related transcription factor overexpression on lignocellulosic inhibitor tolerance of <i>Saccharomyces cerevisiae</i> environmental isolates" @default.
- W3094056769 cites W1483456869 @default.
- W3094056769 cites W1988079922 @default.
- W3094056769 cites W2012654501 @default.
- W3094056769 cites W2012727082 @default.
- W3094056769 cites W2020344646 @default.
- W3094056769 cites W2030674584 @default.
- W3094056769 cites W2033062319 @default.
- W3094056769 cites W2043374634 @default.
- W3094056769 cites W2059595349 @default.
- W3094056769 cites W2065645659 @default.
- W3094056769 cites W2077987592 @default.
- W3094056769 cites W2084504620 @default.
- W3094056769 cites W2092438050 @default.
- W3094056769 cites W2096220064 @default.
- W3094056769 cites W2097547562 @default.
- W3094056769 cites W2102436900 @default.
- W3094056769 cites W2103732169 @default.
- W3094056769 cites W2126916325 @default.
- W3094056769 cites W2131404707 @default.
- W3094056769 cites W2132656684 @default.
- W3094056769 cites W2134293661 @default.
- W3094056769 cites W2134423220 @default.
- W3094056769 cites W2141374544 @default.
- W3094056769 cites W2154839974 @default.
- W3094056769 cites W2157586977 @default.
- W3094056769 cites W2233790635 @default.
- W3094056769 cites W2553988076 @default.
- W3094056769 cites W2769713833 @default.
- W3094056769 cites W2885986222 @default.
- W3094056769 cites W2949477038 @default.
- W3094056769 cites W2951733089 @default.
- W3094056769 cites W4252419751 @default.
- W3094056769 doi "https://doi.org/10.1002/btpr.3094" @default.
- W3094056769 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33085224" @default.
- W3094056769 hasPublicationYear "2020" @default.
- W3094056769 type Work @default.
- W3094056769 sameAs 3094056769 @default.
- W3094056769 citedByCount "3" @default.
- W3094056769 countsByYear W30940567692021 @default.
- W3094056769 countsByYear W30940567692022 @default.
- W3094056769 countsByYear W30940567692023 @default.
- W3094056769 crossrefType "journal-article" @default.
- W3094056769 hasAuthorship W3094056769A5003179197 @default.
- W3094056769 hasAuthorship W3094056769A5028552755 @default.
- W3094056769 hasAuthorship W3094056769A5055014435 @default.
- W3094056769 hasAuthorship W3094056769A5089458184 @default.
- W3094056769 hasConcept C104317684 @default.
- W3094056769 hasConcept C205260736 @default.
- W3094056769 hasConcept C2776667301 @default.
- W3094056769 hasConcept C2777576037 @default.
- W3094056769 hasConcept C55493867 @default.
- W3094056769 hasConcept C68991219 @default.
- W3094056769 hasConcept C86339819 @default.
- W3094056769 hasConcept C86803240 @default.
- W3094056769 hasConcept C95444343 @default.
- W3094056769 hasConceptScore W3094056769C104317684 @default.
- W3094056769 hasConceptScore W3094056769C205260736 @default.
- W3094056769 hasConceptScore W3094056769C2776667301 @default.
- W3094056769 hasConceptScore W3094056769C2777576037 @default.
- W3094056769 hasConceptScore W3094056769C55493867 @default.
- W3094056769 hasConceptScore W3094056769C68991219 @default.
- W3094056769 hasConceptScore W3094056769C86339819 @default.
- W3094056769 hasConceptScore W3094056769C86803240 @default.
- W3094056769 hasConceptScore W3094056769C95444343 @default.
- W3094056769 hasFunder F4320332605 @default.
- W3094056769 hasIssue "2" @default.
- W3094056769 hasLocation W30940567691 @default.
- W3094056769 hasLocation W30940567692 @default.
- W3094056769 hasOpenAccess W3094056769 @default.
- W3094056769 hasPrimaryLocation W30940567691 @default.
- W3094056769 hasRelatedWork W122149059 @default.
- W3094056769 hasRelatedWork W1957495683 @default.
- W3094056769 hasRelatedWork W1975595193 @default.
- W3094056769 hasRelatedWork W1991456063 @default.
- W3094056769 hasRelatedWork W1993912244 @default.
- W3094056769 hasRelatedWork W2037385652 @default.
- W3094056769 hasRelatedWork W2057841153 @default.
- W3094056769 hasRelatedWork W2071960601 @default.
- W3094056769 hasRelatedWork W2376504483 @default.
- W3094056769 hasRelatedWork W3094056769 @default.
- W3094056769 hasVolume "37" @default.
- W3094056769 isParatext "false" @default.
- W3094056769 isRetracted "false" @default.
- W3094056769 magId "3094056769" @default.
- W3094056769 workType "article" @default.