Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094138124> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3094138124 endingPage "4759" @default.
- W3094138124 startingPage "4759" @default.
- W3094138124 abstract "Bacterial nanocellulose has found applications in tissue engineering, in skin tissue repair, and in wound healing. Its large surface area enables the adsorption of various substances. Bacterial nanocellulose with adsorbed substances can serve as a substrate for drug-delivery of specific bioactive healing agents into wounds. In this study, we loaded a bacterial nanocellulose hydrogel with curcumin, i.e., an important anti-bacterial and healing agent, and its degradation products. These products were prepared by thermal decomposition of curcumin (DC) at a temperature of 180 °C (DC 180) or of 300 °C (DC 300). The main thermal decomposition products were tumerone, vanillin, and feruloylmethane. Curcumin and its degradation products were loaded into the bacterial nanocellulose by an autoclaving process. The increased temperature during autoclaving enhanced the solubility and the penetration of the agents into the nanocellulose. The aim of this study was to investigate the cytotoxicity and the antimicrobial activity of pure curcumin, its degradation products, and finally of bacterial nanocellulose loaded with these agents. In vitro tests performed on human dermal fibroblasts revealed that the degradation products of curcumin, i.e., DC 180 and DC 300, were more cytotoxic than pure curcumin. However, if DC 300 was loaded into nanocellulose, the cytotoxic effect was not as strong as in the case of DC 300 powder added into the culture medium. DC 300 was found to be the least soluble product in water, which probably resulted in the poor loading of this agent into the nanocellulose. Nanocellulose loaded with pure curcumin or DC 180 exhibited more antibacterial activity than pristine nanocellulose." @default.
- W3094138124 created "2020-10-29" @default.
- W3094138124 creator A5023493490 @default.
- W3094138124 creator A5029169384 @default.
- W3094138124 creator A5031418128 @default.
- W3094138124 creator A5053410783 @default.
- W3094138124 creator A5071818411 @default.
- W3094138124 creator A5080899016 @default.
- W3094138124 date "2020-10-25" @default.
- W3094138124 modified "2023-10-18" @default.
- W3094138124 title "Effects of Bacterial Nanocellulose Loaded with Curcumin and Its Degradation Products on Human Dermal Fibroblasts" @default.
- W3094138124 cites W1969017801 @default.
- W3094138124 cites W1969257164 @default.
- W3094138124 cites W1982865592 @default.
- W3094138124 cites W1987712541 @default.
- W3094138124 cites W2000826474 @default.
- W3094138124 cites W2023725379 @default.
- W3094138124 cites W2056747169 @default.
- W3094138124 cites W2066165709 @default.
- W3094138124 cites W2070291030 @default.
- W3094138124 cites W2110167136 @default.
- W3094138124 cites W2145418093 @default.
- W3094138124 cites W2174180355 @default.
- W3094138124 cites W2178924239 @default.
- W3094138124 cites W2187236314 @default.
- W3094138124 cites W2305523344 @default.
- W3094138124 cites W2584441194 @default.
- W3094138124 cites W2588942227 @default.
- W3094138124 cites W2598488456 @default.
- W3094138124 cites W2810941281 @default.
- W3094138124 cites W2888099119 @default.
- W3094138124 cites W2893130964 @default.
- W3094138124 cites W2899213265 @default.
- W3094138124 cites W2901404988 @default.
- W3094138124 cites W2911675334 @default.
- W3094138124 cites W2949360967 @default.
- W3094138124 cites W2982353979 @default.
- W3094138124 doi "https://doi.org/10.3390/ma13214759" @default.
- W3094138124 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7663456" @default.
- W3094138124 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33113763" @default.
- W3094138124 hasPublicationYear "2020" @default.
- W3094138124 type Work @default.
- W3094138124 sameAs 3094138124 @default.
- W3094138124 citedByCount "9" @default.
- W3094138124 countsByYear W30941381242021 @default.
- W3094138124 countsByYear W30941381242022 @default.
- W3094138124 countsByYear W30941381242023 @default.
- W3094138124 crossrefType "journal-article" @default.
- W3094138124 hasAuthorship W3094138124A5023493490 @default.
- W3094138124 hasAuthorship W3094138124A5029169384 @default.
- W3094138124 hasAuthorship W3094138124A5031418128 @default.
- W3094138124 hasAuthorship W3094138124A5053410783 @default.
- W3094138124 hasAuthorship W3094138124A5071818411 @default.
- W3094138124 hasAuthorship W3094138124A5080899016 @default.
- W3094138124 hasBestOaLocation W30941381241 @default.
- W3094138124 hasConcept C109316439 @default.
- W3094138124 hasConcept C127413603 @default.
- W3094138124 hasConcept C171250308 @default.
- W3094138124 hasConcept C185592680 @default.
- W3094138124 hasConcept C192562407 @default.
- W3094138124 hasConcept C202751555 @default.
- W3094138124 hasConcept C2777968448 @default.
- W3094138124 hasConcept C2778250585 @default.
- W3094138124 hasConcept C2779251873 @default.
- W3094138124 hasConcept C42360764 @default.
- W3094138124 hasConcept C55493867 @default.
- W3094138124 hasConceptScore W3094138124C109316439 @default.
- W3094138124 hasConceptScore W3094138124C127413603 @default.
- W3094138124 hasConceptScore W3094138124C171250308 @default.
- W3094138124 hasConceptScore W3094138124C185592680 @default.
- W3094138124 hasConceptScore W3094138124C192562407 @default.
- W3094138124 hasConceptScore W3094138124C202751555 @default.
- W3094138124 hasConceptScore W3094138124C2777968448 @default.
- W3094138124 hasConceptScore W3094138124C2778250585 @default.
- W3094138124 hasConceptScore W3094138124C2779251873 @default.
- W3094138124 hasConceptScore W3094138124C42360764 @default.
- W3094138124 hasConceptScore W3094138124C55493867 @default.
- W3094138124 hasIssue "21" @default.
- W3094138124 hasLocation W30941381241 @default.
- W3094138124 hasLocation W30941381242 @default.
- W3094138124 hasLocation W30941381243 @default.
- W3094138124 hasOpenAccess W3094138124 @default.
- W3094138124 hasPrimaryLocation W30941381241 @default.
- W3094138124 hasRelatedWork W1990596206 @default.
- W3094138124 hasRelatedWork W2108738848 @default.
- W3094138124 hasRelatedWork W2195355719 @default.
- W3094138124 hasRelatedWork W2385428541 @default.
- W3094138124 hasRelatedWork W2400888023 @default.
- W3094138124 hasRelatedWork W2748952813 @default.
- W3094138124 hasRelatedWork W2899084033 @default.
- W3094138124 hasRelatedWork W2953014029 @default.
- W3094138124 hasRelatedWork W2991883777 @default.
- W3094138124 hasRelatedWork W3004597754 @default.
- W3094138124 hasVolume "13" @default.
- W3094138124 isParatext "false" @default.
- W3094138124 isRetracted "false" @default.
- W3094138124 magId "3094138124" @default.
- W3094138124 workType "article" @default.