FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094553814> ?p ?o ?g. }

• W3094553814 endingPage "S1310" @default.
• W3094553814 startingPage "S1310" @default.
• W3094553814 abstract "INTRODUCTION: Recent studies have suggested that COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-20), can cause abnormal liver function tests (LFT) in affected patients both with and without pre-existing liver disease. Here we describe a series of patient cases involving abnormal LFTs in patients with confirmed COVID-19 infections in both the inpatient and outpatient setting at the Mayo Clinic in Florida. CASE DESCRIPTION/METHODS: 4 cases of COVID-19 infection with concomitant abnormal LFTs were identified. Only 1 of the 4 patients required hospital admission while three other patients were managed on an outpatient basis. 1 patient was managed completely outpatient, 2 patients required an emergency department visit, and the last patient was hospitalized and admitted to the ICU. 3/4 patients had no pre-existing liver conditions, while 1 patient had findings suggestive of nonalcoholic fatty liver disease (NAFLD) on imaging with no prior diagnosis. Only 2 out of 4 patients had gastrointestinal symptoms including nausea, abdominal pain, and diarrhea. All patients recovered from COVID-19 with no major sequelae and their LFTs returned to baseline levels with no major intervention. 2 out of 4 patients were given hydroxychloroquine as part of their treatment. The average max aspartate transaminase (AST) and alanine transaminase (ALT) among all patients were 206 ± 58.7 and 313 ± 155, respectively. No significant pattern was seen between elevations of AST vs ALT. Notably, all patients had abnormal AST and ALT, but only 1 patient had elevated ALP. Bilirubin was not affected in all patients. DISCUSSION: In the literature, there have been reports of abnormal liver function tests associated with SARS-CoV2. In many of these reports, only a small subset of patients had pre-existing liver conditions (< 10%). This suggests that there are unknown variables involved in COVID-19 infection that leads to liver injury. Severe illness leading to shock, hypoxia, or inflammation can all affect the liver, independently of the SARS-CoV-2 virus. Only one patient in the series was hospitalized, and all patients recovered from their disease over the course of 2 weeks. Other possible mechanisms include direct damage of liver cells by the virus or treatment associated drug hepatoxicity. Further studies are needed to evaluate the association between liver injury and the SARS-CoV-2 virus." @default.
• W3094553814 created "2020-10-29" @default.
• W3094553814 creator A5070527656 @default.
• W3094553814 creator A5070602404 @default.
• W3094553814 date "2020-10-01" @default.
• W3094553814 modified "2023-10-16" @default.
• W3094553814 title "S2478 A Case Series of Four Patients and Elevated Transaminases Associated With Acute COVID-19 Infection" @default.
• W3094553814 doi "https://doi.org/10.14309/01.ajg.0000711960.38124.03" @default.
• W3094553814 hasPublicationYear "2020" @default.
• W3094553814 type Work @default.
• W3094553814 sameAs 3094553814 @default.
• W3094553814 citedByCount "0" @default.
• W3094553814 crossrefType "journal-article" @default.
• W3094553814 hasAuthorship W3094553814A5070527656 @default.
• W3094553814 hasAuthorship W3094553814A5070602404 @default.
• W3094553814 hasBestOaLocation W30945538141 @default.
• W3094553814 hasConcept C118552586 @default.
• W3094553814 hasConcept C126322002 @default.
• W3094553814 hasConcept C160160445 @default.
• W3094553814 hasConcept C181199279 @default.
• W3094553814 hasConcept C185592680 @default.
• W3094553814 hasConcept C2777075537 @default.
• W3094553814 hasConcept C2778606649 @default.
• W3094553814 hasConcept C2779123688 @default.
• W3094553814 hasConcept C2779134260 @default.
• W3094553814 hasConcept C2779384505 @default.
• W3094553814 hasConcept C2779679107 @default.
• W3094553814 hasConcept C2780567839 @default.
• W3094553814 hasConcept C2780580376 @default.
• W3094553814 hasConcept C2780724011 @default.
• W3094553814 hasConcept C2780955771 @default.
• W3094553814 hasConcept C2992208098 @default.
• W3094553814 hasConcept C3008058167 @default.
• W3094553814 hasConcept C3020110884 @default.
• W3094553814 hasConcept C512861765 @default.
• W3094553814 hasConcept C524204448 @default.
• W3094553814 hasConcept C55493867 @default.
• W3094553814 hasConcept C71924100 @default.
• W3094553814 hasConcept C90924648 @default.
• W3094553814 hasConceptScore W3094553814C118552586 @default.
• W3094553814 hasConceptScore W3094553814C126322002 @default.
• W3094553814 hasConceptScore W3094553814C160160445 @default.
• W3094553814 hasConceptScore W3094553814C181199279 @default.
• W3094553814 hasConceptScore W3094553814C185592680 @default.
• W3094553814 hasConceptScore W3094553814C2777075537 @default.
• W3094553814 hasConceptScore W3094553814C2778606649 @default.
• W3094553814 hasConceptScore W3094553814C2779123688 @default.
• W3094553814 hasConceptScore W3094553814C2779134260 @default.
• W3094553814 hasConceptScore W3094553814C2779384505 @default.
• W3094553814 hasConceptScore W3094553814C2779679107 @default.
• W3094553814 hasConceptScore W3094553814C2780567839 @default.
• W3094553814 hasConceptScore W3094553814C2780580376 @default.
• W3094553814 hasConceptScore W3094553814C2780724011 @default.
• W3094553814 hasConceptScore W3094553814C2780955771 @default.
• W3094553814 hasConceptScore W3094553814C2992208098 @default.
• W3094553814 hasConceptScore W3094553814C3008058167 @default.
• W3094553814 hasConceptScore W3094553814C3020110884 @default.
• W3094553814 hasConceptScore W3094553814C512861765 @default.
• W3094553814 hasConceptScore W3094553814C524204448 @default.
• W3094553814 hasConceptScore W3094553814C55493867 @default.
• W3094553814 hasConceptScore W3094553814C71924100 @default.
• W3094553814 hasConceptScore W3094553814C90924648 @default.
• W3094553814 hasIssue "1" @default.
• W3094553814 hasLocation W30945538141 @default.
• W3094553814 hasLocation W30945538142 @default.
• W3094553814 hasOpenAccess W3094553814 @default.
• W3094553814 hasPrimaryLocation W30945538141 @default.
• W3094553814 hasRelatedWork W1832604137 @default.
• W3094553814 hasRelatedWork W2019834719 @default.
• W3094553814 hasRelatedWork W2042430160 @default.
• W3094553814 hasRelatedWork W2298379609 @default.
• W3094553814 hasRelatedWork W2558360119 @default.
• W3094553814 hasRelatedWork W2908055317 @default.
• W3094553814 hasRelatedWork W2942261013 @default.
• W3094553814 hasRelatedWork W3032341092 @default.
• W3094553814 hasRelatedWork W307921490 @default.
• W3094553814 hasRelatedWork W4207054562 @default.
• W3094553814 hasVolume "115" @default.
• W3094553814 isParatext "false" @default.
• W3094553814 isRetracted "false" @default.
• W3094553814 magId "3094553814" @default.
• W3094553814 workType "article" @default.