Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094599088> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3094599088 abstract "This review is devoted to the actual for the present day problem of the hepatotoxicity of chemotherapeutic agents. Liver is the most important organ essential for the maintaining of the body’s internal environment. For the present time there is observed the high level of the morbidity and mortality rate against the background of drug-induced liver lesions due to, in the first instance, the lack ofproper manner for the substitution of the liver function but transplantation. Liver deteriorations due to the administration of antitumor agents have no pathognomonic clinical or histological features that significantly embarrasses the execution of the differential diagnosis with liver disorders against the background of administration of other preparations, either associated with opportunistic infections or the progression of previously acquired pathology of the liver. In the article there is described the toxic influence on the liver of most often used in oncology chemotherapeutic agents - antimetabolites, alkylating agents, platinum compounds, epothilones, taxanes, vinca alkaloids, monoclonal antibodies, anthracycline antibiotics, topoisomerase and protein kinase inhibitors is described in this article. In the review there are summarized results of recent studies of etiology, pathogenesis, clinical features, diagnosis, prevention and treatment of chemotherapy induced hepatotoxicity. The special attention is given to recent discoveries in the area of pathogenesis of chemotherapy induced hepatotoxicity. However many moments remain to be still not studied completely, that offers perspectives for further research in this field." @default.
- W3094599088 created "2020-10-29" @default.
- W3094599088 creator A5012617092 @default.
- W3094599088 creator A5022195501 @default.
- W3094599088 creator A5036106942 @default.
- W3094599088 creator A5051350062 @default.
- W3094599088 creator A5057124571 @default.
- W3094599088 creator A5058182379 @default.
- W3094599088 creator A5075313380 @default.
- W3094599088 creator A5077489851 @default.
- W3094599088 creator A5090113035 @default.
- W3094599088 creator A5090931080 @default.
- W3094599088 date "2016-12-15" @default.
- W3094599088 modified "2023-09-27" @default.
- W3094599088 title "Hepatotoxicity of chemotherapeutic agents: current state of the problem" @default.
- W3094599088 cites W2024937208 @default.
- W3094599088 cites W2061910554 @default.
- W3094599088 cites W2071385801 @default.
- W3094599088 cites W2075816945 @default.
- W3094599088 cites W2087256708 @default.
- W3094599088 cites W2106602049 @default.
- W3094599088 cites W2134449164 @default.
- W3094599088 cites W2165788910 @default.
- W3094599088 doi "https://doi.org/10.18821/1028-9984-2016-21-6-325-333" @default.
- W3094599088 hasPublicationYear "2016" @default.
- W3094599088 type Work @default.
- W3094599088 sameAs 3094599088 @default.
- W3094599088 citedByCount "3" @default.
- W3094599088 countsByYear W30945990882020 @default.
- W3094599088 countsByYear W30945990882022 @default.
- W3094599088 crossrefType "journal-article" @default.
- W3094599088 hasAuthorship W3094599088A5012617092 @default.
- W3094599088 hasAuthorship W3094599088A5022195501 @default.
- W3094599088 hasAuthorship W3094599088A5036106942 @default.
- W3094599088 hasAuthorship W3094599088A5051350062 @default.
- W3094599088 hasAuthorship W3094599088A5057124571 @default.
- W3094599088 hasAuthorship W3094599088A5058182379 @default.
- W3094599088 hasAuthorship W3094599088A5075313380 @default.
- W3094599088 hasAuthorship W3094599088A5077489851 @default.
- W3094599088 hasAuthorship W3094599088A5090113035 @default.
- W3094599088 hasAuthorship W3094599088A5090931080 @default.
- W3094599088 hasConcept C121608353 @default.
- W3094599088 hasConcept C126322002 @default.
- W3094599088 hasConcept C203014093 @default.
- W3094599088 hasConcept C2776694085 @default.
- W3094599088 hasConcept C2776802502 @default.
- W3094599088 hasConcept C2779609443 @default.
- W3094599088 hasConcept C2780035454 @default.
- W3094599088 hasConcept C2780942790 @default.
- W3094599088 hasConcept C2911091166 @default.
- W3094599088 hasConcept C530470458 @default.
- W3094599088 hasConcept C71924100 @default.
- W3094599088 hasConcept C98274493 @default.
- W3094599088 hasConceptScore W3094599088C121608353 @default.
- W3094599088 hasConceptScore W3094599088C126322002 @default.
- W3094599088 hasConceptScore W3094599088C203014093 @default.
- W3094599088 hasConceptScore W3094599088C2776694085 @default.
- W3094599088 hasConceptScore W3094599088C2776802502 @default.
- W3094599088 hasConceptScore W3094599088C2779609443 @default.
- W3094599088 hasConceptScore W3094599088C2780035454 @default.
- W3094599088 hasConceptScore W3094599088C2780942790 @default.
- W3094599088 hasConceptScore W3094599088C2911091166 @default.
- W3094599088 hasConceptScore W3094599088C530470458 @default.
- W3094599088 hasConceptScore W3094599088C71924100 @default.
- W3094599088 hasConceptScore W3094599088C98274493 @default.
- W3094599088 hasLocation W30945990881 @default.
- W3094599088 hasOpenAccess W3094599088 @default.
- W3094599088 hasPrimaryLocation W30945990881 @default.
- W3094599088 hasRelatedWork W1720158387 @default.
- W3094599088 hasRelatedWork W2021857815 @default.
- W3094599088 hasRelatedWork W2071231229 @default.
- W3094599088 hasRelatedWork W2076499890 @default.
- W3094599088 hasRelatedWork W2133624390 @default.
- W3094599088 hasRelatedWork W2148681504 @default.
- W3094599088 hasRelatedWork W2334540822 @default.
- W3094599088 hasRelatedWork W2392718945 @default.
- W3094599088 hasRelatedWork W2807046640 @default.
- W3094599088 hasRelatedWork W2809066589 @default.
- W3094599088 hasRelatedWork W2902042937 @default.
- W3094599088 hasRelatedWork W2924735222 @default.
- W3094599088 hasRelatedWork W2924937158 @default.
- W3094599088 hasRelatedWork W3034011920 @default.
- W3094599088 hasRelatedWork W3133194956 @default.
- W3094599088 hasRelatedWork W3179374467 @default.
- W3094599088 hasRelatedWork W3182054210 @default.
- W3094599088 hasRelatedWork W3187731595 @default.
- W3094599088 hasRelatedWork W3202930700 @default.
- W3094599088 hasRelatedWork W3027769374 @default.
- W3094599088 isParatext "false" @default.
- W3094599088 isRetracted "false" @default.
- W3094599088 magId "3094599088" @default.
- W3094599088 workType "article" @default.