Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094788013> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3094788013 endingPage "768" @default.
- W3094788013 startingPage "762" @default.
- W3094788013 abstract "BACKGROUND: The normoglycemic patients with diabetes risk and prediabetes have insulin resistance and consequently endothelial dysfunction that possible causes macroangiopathy and adverse cardiovascular events and further mortality of it. An early diabetes risk identification using not only prognostic scales but also biomarkers is starting and crucial point of struggle with 2 type diabetes mellitus and its complications.
 AIM: The aim of the study is to estimate the impact of FABP4 biomarker on diabetes risk and cardiovascular events.
 METHODS: A cross-sectional study was conducted simultaneously among 389 respondents aged 18–65 years. We provided survey and clinical examinations. The risk of diabetes was assessed using the FINDRISC scale and cardiovascular risk (CVR) was assessed using SCORE scale.
 The serum FABP4 biomarker was studied using a multiplex assay, immunofluorescence using XMap technology, a Bioplex 3D instrument, and a MILLIPLEX® Human cardiovascular disease panel I reagent kit(Millipore). Results were considered statistically significant at p < 0.001.
 RESULTS: The group of type 2 diabetes mellitus (T2DM) high risk was 79 (20%) of all study participants. The level of the FABP4 marker significantly prevailed in high-risk group of T2DM and high CVR was also established this group. We found a positive direct average correlation(r = 0.59; p = 0.000) between FABP4 and FINDRISC scale. The logistic regression analysis indicated that the level of the FABP4 marker increases withing the increased risk of T2DM. The correlation between FABP4 concentration and CVR according to the SCORE scale (r = 0.24; p = 0,000) was lower than between FABP4 and diabetes risk. Risk factors were established affecting on the increasing CVR by SCORE scale in patients with T2DM risk.
 CONCLUSIONS: The level of FABP4 significantly prevailed in the group of diabetes and cardiovascular risk (CVR). The established correlations between FABP4 level and CVR or T2DM risk indicate on its increase in groups with a higher risk of type 2 diabetes and a high CVR." @default.
- W3094788013 created "2020-11-09" @default.
- W3094788013 creator A5000555581 @default.
- W3094788013 creator A5023534979 @default.
- W3094788013 creator A5043353841 @default.
- W3094788013 creator A5046081839 @default.
- W3094788013 creator A5046700665 @default.
- W3094788013 creator A5046766206 @default.
- W3094788013 creator A5046825412 @default.
- W3094788013 date "2020-10-10" @default.
- W3094788013 modified "2023-09-26" @default.
- W3094788013 title "The Relationship Between the Level Fabp4, Risks of Type 2 Diabetes Mellitus, and Cardiovascular Events" @default.
- W3094788013 cites W1493695112 @default.
- W3094788013 cites W1966876552 @default.
- W3094788013 cites W1972102243 @default.
- W3094788013 cites W1999783468 @default.
- W3094788013 cites W2027875236 @default.
- W3094788013 cites W2040575305 @default.
- W3094788013 cites W2084532791 @default.
- W3094788013 cites W2085087376 @default.
- W3094788013 cites W2087287221 @default.
- W3094788013 cites W2090911565 @default.
- W3094788013 cites W2109374123 @default.
- W3094788013 cites W2113570079 @default.
- W3094788013 cites W2120471801 @default.
- W3094788013 cites W2133374684 @default.
- W3094788013 cites W2278860456 @default.
- W3094788013 cites W2535658838 @default.
- W3094788013 cites W2775937882 @default.
- W3094788013 doi "https://doi.org/10.3889/oamjms.2020.4678" @default.
- W3094788013 hasPublicationYear "2020" @default.
- W3094788013 type Work @default.
- W3094788013 sameAs 3094788013 @default.
- W3094788013 citedByCount "0" @default.
- W3094788013 crossrefType "journal-article" @default.
- W3094788013 hasAuthorship W3094788013A5000555581 @default.
- W3094788013 hasAuthorship W3094788013A5023534979 @default.
- W3094788013 hasAuthorship W3094788013A5043353841 @default.
- W3094788013 hasAuthorship W3094788013A5046081839 @default.
- W3094788013 hasAuthorship W3094788013A5046700665 @default.
- W3094788013 hasAuthorship W3094788013A5046766206 @default.
- W3094788013 hasAuthorship W3094788013A5046825412 @default.
- W3094788013 hasBestOaLocation W30947880132 @default.
- W3094788013 hasConcept C11783203 @default.
- W3094788013 hasConcept C126322002 @default.
- W3094788013 hasConcept C134018914 @default.
- W3094788013 hasConcept C151956035 @default.
- W3094788013 hasConcept C185592680 @default.
- W3094788013 hasConcept C2777180221 @default.
- W3094788013 hasConcept C2777391703 @default.
- W3094788013 hasConcept C2779134260 @default.
- W3094788013 hasConcept C2779306644 @default.
- W3094788013 hasConcept C2779668308 @default.
- W3094788013 hasConcept C2781197716 @default.
- W3094788013 hasConcept C2910068830 @default.
- W3094788013 hasConcept C55493867 @default.
- W3094788013 hasConcept C555293320 @default.
- W3094788013 hasConcept C71924100 @default.
- W3094788013 hasConceptScore W3094788013C11783203 @default.
- W3094788013 hasConceptScore W3094788013C126322002 @default.
- W3094788013 hasConceptScore W3094788013C134018914 @default.
- W3094788013 hasConceptScore W3094788013C151956035 @default.
- W3094788013 hasConceptScore W3094788013C185592680 @default.
- W3094788013 hasConceptScore W3094788013C2777180221 @default.
- W3094788013 hasConceptScore W3094788013C2777391703 @default.
- W3094788013 hasConceptScore W3094788013C2779134260 @default.
- W3094788013 hasConceptScore W3094788013C2779306644 @default.
- W3094788013 hasConceptScore W3094788013C2779668308 @default.
- W3094788013 hasConceptScore W3094788013C2781197716 @default.
- W3094788013 hasConceptScore W3094788013C2910068830 @default.
- W3094788013 hasConceptScore W3094788013C55493867 @default.
- W3094788013 hasConceptScore W3094788013C555293320 @default.
- W3094788013 hasConceptScore W3094788013C71924100 @default.
- W3094788013 hasIssue "B" @default.
- W3094788013 hasLocation W30947880131 @default.
- W3094788013 hasLocation W30947880132 @default.
- W3094788013 hasOpenAccess W3094788013 @default.
- W3094788013 hasPrimaryLocation W30947880131 @default.
- W3094788013 hasRelatedWork W10601693 @default.
- W3094788013 hasRelatedWork W11504938 @default.
- W3094788013 hasRelatedWork W15647580 @default.
- W3094788013 hasRelatedWork W2474835 @default.
- W3094788013 hasRelatedWork W2711290 @default.
- W3094788013 hasRelatedWork W4656229 @default.
- W3094788013 hasRelatedWork W8744681 @default.
- W3094788013 hasRelatedWork W9343845 @default.
- W3094788013 hasRelatedWork W16605058 @default.
- W3094788013 hasRelatedWork W7192389 @default.
- W3094788013 hasVolume "8" @default.
- W3094788013 isParatext "false" @default.
- W3094788013 isRetracted "false" @default.
- W3094788013 magId "3094788013" @default.
- W3094788013 workType "article" @default.