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- W3094796552 abstract "Abstract Cryptosporidium spp. are one of the most important waterborne pathogens worldwide and a leading cause of mortality from waterborne gastrointestinal diseases. Detection of Cryptosporidium spp. in water can be very challenging due to their low numbers and the complexity of the water matrix. This review describes the biology of Cryptosporidium spp. and current methods used in their detection with a focus on C. parvum and C. hominis. Among the methods discussed and compared are microscopy, immunology-based methods using monoclonal antibodies, molecular methods including PCR (polymerase chain reaction)-based assays, and emerging aptamer-based methods. These methods have different capabilities and limitations, but one common challenge is the need for better sensitivity and specificity, particularly in the presence of contaminants. The application of DNA aptamers in the detection of Cryptosporidium spp. oocysts shows promise in overcoming these challenges, and there will likely be significant developments in aptamer-based sensors in the near future." @default.
- W3094796552 created "2020-11-09" @default.
- W3094796552 creator A5018807952 @default.
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- W3094796552 creator A5047896581 @default.
- W3094796552 creator A5056785214 @default.
- W3094796552 creator A5062256395 @default.
- W3094796552 creator A5066891093 @default.
- W3094796552 date "2020-10-28" @default.
- W3094796552 modified "2023-10-17" @default.
- W3094796552 title "A review of<i>Cryptosporidium</i>spp. and their detection in water" @default.
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