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• W3094845437 abstract "In this work, the cytotoxic behavior of six ruthenium(II) complexes of stoichiometry [(η6-p-cymene)RuCl2L] (I-VI), L = 4-cyanopyridine (I), 2-aminophenol (II), 4-aminophenol (III), pyridazine (IV), and [(η6-p-cymene)RuClL2]PF6; L = cyanopyridine (V), L = 2-aminophenol(VI) towards three cell lines was studied. Two of them, HeLa and MCF-7, are human carcinogenic cells from cervical carcinoma and human breast cancer, respectively. A comparison with healthy cells was carried out with BGM cells which are monkey epithelial cells of renal origin. The behavior of complex II exhibits selectivity towards healthy cells, which is a promising feature for use in cancer treatment since it might reduce the side effects of most current therapies." @default.
• W3094845437 created "2020-11-09" @default.
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• W3094845437 date "2020-10-31" @default.
• W3094845437 modified "2023-10-12" @default.
• W3094845437 title "p-Cymene Complexes of Ruthenium(II) as Antitumor Agents" @default.
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• W3094845437 doi "https://doi.org/10.3390/molecules25215063" @default.
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