FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094870867> ?p ?o ?g. }

• W3094870867 abstract "Excess alcohol intake and inherited predisposition may increase risk of atrial fibrillation (AF). We assessed the association between alcohol intake, polygenic predisposition to AF, and incident AF in the UK Biobank, a prospective cohort study.In 376 776 UK Biobank participants enrolled between 2006 and 2010, we tested alcohol consumption (stratified by the Centers of Disease Control and Prevention acceptable range of ≤98 g/wk for women or ≤196 g/wk for men; and as a continuous variable) and an AF polygenic risk score for association with incident AF.Among participants (47.5% male, mean age 56.9 years), 6293 developed AF during a median of 6.9 years of follow-up. Alcohol consumption was associated with AF (hazard ratio, 1.10 [95% CI, 1.05-1.16] for intake above an acceptable range; hazard ratio, 1.04 per 100 g/wk [95% CI, 1.02-1.06]). An AF polygenic risk score was associated with AF (hazard ratio, 1.38 per SD [95% CI, 1.35-1.41]). In models including both alcohol and the AF polygenic risk score, each remained associated with AF. The 5-year cumulative risk of AF for individuals with alcohol intake above an acceptable range and in the highest decile of polygenic risk was 2.33% (95% CI, 2.07-2.59), compared with 0.69% (95% CI, 0.58-0.80) for those with alcohol intake within an acceptable range and in the lowest decile of polygenic risk.Alcohol consumption is associated with increased risk of AF across a range of polygenic predisposition to AF and adds to inherited and clinical predisposition to increase AF susceptibility. Preventive efforts focused on minimizing alcohol intake may be broadly applicable." @default.
• W3094870867 created "2020-11-09" @default.
• W3094870867 creator A5005968538 @default.
• W3094870867 creator A5014513186 @default.
• W3094870867 creator A5021812898 @default.
• W3094870867 creator A5033626404 @default.
• W3094870867 creator A5041028758 @default.
• W3094870867 creator A5041586675 @default.
• W3094870867 creator A5042984133 @default.
• W3094870867 creator A5064309113 @default.
• W3094870867 creator A5069822855 @default.
• W3094870867 creator A5084721457 @default.
• W3094870867 date "2020-12-01" @default.
• W3094870867 modified "2023-10-15" @default.
• W3094870867 title "Associations Between Alcohol Intake and Genetic Predisposition With Atrial Fibrillation Risk in a National Biobank" @default.
• W3094870867 cites W17250226 @default.
• W3094870867 cites W1805190232 @default.
• W3094870867 cites W1924098982 @default.
• W3094870867 cites W2002894524 @default.
• W3094870867 cites W2041827270 @default.
• W3094870867 cites W2045829317 @default.
• W3094870867 cites W2086418097 @default.
• W3094870867 cites W2097173178 @default.
• W3094870867 cites W2100149246 @default.
• W3094870867 cites W2123086604 @default.
• W3094870867 cites W2123620954 @default.
• W3094870867 cites W2124719424 @default.
• W3094870867 cites W2341280085 @default.
• W3094870867 cites W2519124963 @default.
• W3094870867 cites W2560835297 @default.
• W3094870867 cites W2593548862 @default.
• W3094870867 cites W2607238069 @default.
• W3094870867 cites W2740563274 @default.
• W3094870867 cites W2767002255 @default.
• W3094870867 cites W2803332630 @default.
• W3094870867 cites W2804551710 @default.
• W3094870867 cites W2810472113 @default.
• W3094870867 cites W2901081400 @default.
• W3094870867 cites W2984114374 @default.
• W3094870867 cites W2984766121 @default.
• W3094870867 cites W2997250629 @default.
• W3094870867 cites W4210728383 @default.
• W3094870867 doi "https://doi.org/10.1161/circgen.120.003111" @default.
• W3094870867 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7738370" @default.
• W3094870867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33156697" @default.
• W3094870867 hasPublicationYear "2020" @default.
• W3094870867 type Work @default.
• W3094870867 sameAs 3094870867 @default.
• W3094870867 citedByCount "3" @default.
• W3094870867 countsByYear W30948708672021 @default.
• W3094870867 countsByYear W30948708672022 @default.
• W3094870867 countsByYear W30948708672023 @default.
• W3094870867 crossrefType "journal-article" @default.
• W3094870867 hasAuthorship W3094870867A5005968538 @default.
• W3094870867 hasAuthorship W3094870867A5014513186 @default.
• W3094870867 hasAuthorship W3094870867A5021812898 @default.
• W3094870867 hasAuthorship W3094870867A5033626404 @default.
• W3094870867 hasAuthorship W3094870867A5041028758 @default.
• W3094870867 hasAuthorship W3094870867A5041586675 @default.
• W3094870867 hasAuthorship W3094870867A5042984133 @default.
• W3094870867 hasAuthorship W3094870867A5064309113 @default.
• W3094870867 hasAuthorship W3094870867A5069822855 @default.
• W3094870867 hasAuthorship W3094870867A5084721457 @default.
• W3094870867 hasBestOaLocation W30948708671 @default.
• W3094870867 hasConcept C126322002 @default.
• W3094870867 hasConcept C144024400 @default.
• W3094870867 hasConcept C149923435 @default.
• W3094870867 hasConcept C188816634 @default.
• W3094870867 hasConcept C207103383 @default.
• W3094870867 hasConcept C2779161974 @default.
• W3094870867 hasConcept C44249647 @default.
• W3094870867 hasConcept C50382708 @default.
• W3094870867 hasConcept C71924100 @default.
• W3094870867 hasConcept C72563966 @default.
• W3094870867 hasConceptScore W3094870867C126322002 @default.
• W3094870867 hasConceptScore W3094870867C144024400 @default.
• W3094870867 hasConceptScore W3094870867C149923435 @default.
• W3094870867 hasConceptScore W3094870867C188816634 @default.
• W3094870867 hasConceptScore W3094870867C207103383 @default.
• W3094870867 hasConceptScore W3094870867C2779161974 @default.
• W3094870867 hasConceptScore W3094870867C44249647 @default.
• W3094870867 hasConceptScore W3094870867C50382708 @default.
• W3094870867 hasConceptScore W3094870867C71924100 @default.
• W3094870867 hasConceptScore W3094870867C72563966 @default.
• W3094870867 hasIssue "6" @default.
• W3094870867 hasLocation W30948708671 @default.
• W3094870867 hasLocation W30948708672 @default.
• W3094870867 hasLocation W30948708673 @default.
• W3094870867 hasOpenAccess W3094870867 @default.
• W3094870867 hasPrimaryLocation W30948708671 @default.
• W3094870867 hasRelatedWork W1973635299 @default.
• W3094870867 hasRelatedWork W2039276365 @default.
• W3094870867 hasRelatedWork W2159483167 @default.
• W3094870867 hasRelatedWork W2174666533 @default.
• W3094870867 hasRelatedWork W2760462550 @default.
• W3094870867 hasRelatedWork W2791790237 @default.
• W3094870867 hasRelatedWork W2795086318 @default.
• W3094870867 hasRelatedWork W2889106228 @default.
• W3094870867 hasRelatedWork W4210426024 @default.
• W3094870867 hasRelatedWork W4229009061 @default.

• next