FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094959825> ?p ?o ?g. }

• W3094959825 abstract "Abstract HIV-1 diversity may impact monitoring and vaccine development. We describe the most recent data of HIV-1 variants and their temporal trends in the Democratic Republic of Congo (DRC) from 1976 to 2018 and in Kinshasa from 1983–2018. HIV-1 pol sequencing from dried blood collected in Kinshasa during 2016–2018 was done in 340 HIV-infected children/adolescents/adults to identify HIV-1 variants by phylogenetic reconstructions. Recombination events and transmission clusters were also analyzed. Variant distribution and genetic diversity were compared to historical available pol sequences from the DRC in Los Alamos Database (LANL). We characterized 165 HIV-1 pol variants circulating in Kinshasa (2016–2018) and compared them with 2641 LANL sequences from the DRC (1976–2012) and Kinshasa (1983–2008). During 2016–2018 the main subtypes were A (26.7%), G (9.7%) and C (7.3%). Recombinants accounted for a third of infections (12.7%/23.6% Circulant/Unique Recombinant Forms). We identified the first CRF47_BF reported in Africa and four transmission clusters. A significant increase of subtype A and sub-subtype F1 and a significant reduction of sub-subtype A1 and subtype D were observed in Kinshasa during 2016–2018 compared to variants circulating in the city from 1983 to 2008. We provide unique and updated information related to HIV-1 variants currently circulating in Kinshasa, reporting the temporal trends of subtypes/CRF/URF during 43 years in the DRC, and providing the most extensive data on children/adolescents." @default.
• W3094959825 created "2020-11-09" @default.
• W3094959825 creator A5031229019 @default.
• W3094959825 creator A5046067520 @default.
• W3094959825 creator A5054737399 @default.
• W3094959825 creator A5074041179 @default.
• W3094959825 creator A5080453261 @default.
• W3094959825 creator A5087432966 @default.
• W3094959825 creator A5088233740 @default.
• W3094959825 creator A5090456955 @default.
• W3094959825 date "2020-10-28" @default.
• W3094959825 modified "2023-10-14" @default.
• W3094959825 title "Current and historic HIV-1 molecular epidemiology in paediatric and adult population from Kinshasa in the Democratic Republic of Congo" @default.
• W3094959825 cites W1518187558 @default.
• W3094959825 cites W1624000424 @default.
• W3094959825 cites W1972617906 @default.
• W3094959825 cites W1981304838 @default.
• W3094959825 cites W1985308057 @default.
• W3094959825 cites W1989468850 @default.
• W3094959825 cites W1993646412 @default.
• W3094959825 cites W2003172880 @default.
• W3094959825 cites W2004669329 @default.
• W3094959825 cites W2005795274 @default.
• W3094959825 cites W2021906926 @default.
• W3094959825 cites W2022055721 @default.
• W3094959825 cites W2031611770 @default.
• W3094959825 cites W2033379456 @default.
• W3094959825 cites W2042930510 @default.
• W3094959825 cites W2046159909 @default.
• W3094959825 cites W2050857761 @default.
• W3094959825 cites W2053335284 @default.
• W3094959825 cites W2054050532 @default.
• W3094959825 cites W2056269012 @default.
• W3094959825 cites W2060877912 @default.
• W3094959825 cites W2061819014 @default.
• W3094959825 cites W2064702350 @default.
• W3094959825 cites W2068391849 @default.
• W3094959825 cites W2070505454 @default.
• W3094959825 cites W2083224850 @default.
• W3094959825 cites W2090407774 @default.
• W3094959825 cites W2093680134 @default.
• W3094959825 cites W2104878638 @default.
• W3094959825 cites W2110538282 @default.
• W3094959825 cites W2124409966 @default.
• W3094959825 cites W2124627199 @default.
• W3094959825 cites W2126183065 @default.
• W3094959825 cites W2140185492 @default.
• W3094959825 cites W2141008678 @default.
• W3094959825 cites W2141052558 @default.
• W3094959825 cites W2142153651 @default.
• W3094959825 cites W2144975624 @default.
• W3094959825 cites W2148970839 @default.
• W3094959825 cites W2149445861 @default.
• W3094959825 cites W2153163225 @default.
• W3094959825 cites W2154963941 @default.
• W3094959825 cites W2158666214 @default.
• W3094959825 cites W2160179097 @default.
• W3094959825 cites W2162727140 @default.
• W3094959825 cites W2397476479 @default.
• W3094959825 cites W2399455523 @default.
• W3094959825 cites W2470785107 @default.
• W3094959825 cites W2509272344 @default.
• W3094959825 cites W2535014449 @default.
• W3094959825 cites W2571541240 @default.
• W3094959825 cites W2578877835 @default.
• W3094959825 cites W2598381200 @default.
• W3094959825 cites W2767968516 @default.
• W3094959825 cites W2775910518 @default.
• W3094959825 cites W2793085614 @default.
• W3094959825 cites W2804049532 @default.
• W3094959825 cites W2903314774 @default.
• W3094959825 cites W2932596990 @default.
• W3094959825 cites W2935539603 @default.
• W3094959825 cites W2950255151 @default.
• W3094959825 cites W2984243262 @default.
• W3094959825 cites W2989220201 @default.
• W3094959825 cites W3006135412 @default.
• W3094959825 cites W3008033034 @default.
• W3094959825 cites W3026205718 @default.
• W3094959825 doi "https://doi.org/10.1038/s41598-020-74558-z" @default.
• W3094959825 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7595211" @default.
• W3094959825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33116151" @default.
• W3094959825 hasPublicationYear "2020" @default.
• W3094959825 type Work @default.
• W3094959825 sameAs 3094959825 @default.
• W3094959825 citedByCount "9" @default.
• W3094959825 countsByYear W30949598252021 @default.
• W3094959825 countsByYear W30949598252022 @default.
• W3094959825 countsByYear W30949598252023 @default.
• W3094959825 crossrefType "journal-article" @default.
• W3094959825 hasAuthorship W3094959825A5031229019 @default.
• W3094959825 hasAuthorship W3094959825A5046067520 @default.
• W3094959825 hasAuthorship W3094959825A5054737399 @default.
• W3094959825 hasAuthorship W3094959825A5074041179 @default.
• W3094959825 hasAuthorship W3094959825A5080453261 @default.
• W3094959825 hasAuthorship W3094959825A5087432966 @default.
• W3094959825 hasAuthorship W3094959825A5088233740 @default.
• W3094959825 hasAuthorship W3094959825A5090456955 @default.
• W3094959825 hasBestOaLocation W30949598251 @default.
• W3094959825 hasConcept C104317684 @default.

• next