Matches in SemOpenAlex for { <https://semopenalex.org/work/W3094965993> ?p ?o ?g. }
- W3094965993 abstract "There is emerging evidence for abnormal beta oscillations in psychosis. Beta oscillations are likely to play a key role in the coordination of sensorimotor information that is crucial to healthy mental function. Growing evidence suggests that beta oscillations typically manifest as transient beta bursts that increase in probability following a motor response, observable as post-movement beta rebound. Evidence indicates that post-movement beta rebound is attenuated in psychosis, with greater attenuation associated with greater symptom severity and impairment. Delineating the functional role of beta bursts therefore may be key to understanding the mechanisms underlying persistent psychotic illness.We used concurrent electroencephalography and functional magnetic resonance imaging to identify blood oxygen level-dependent correlates of beta bursts during the n-back working memory task and intervening rest periods in healthy control participants (n = 30) and patients with psychosis (n = 48).During both task blocks and intervening rest periods, beta bursts phasically activated regions implicated in task-relevant content while suppressing currently tonically active regions. Patients showed attenuated post-movement beta rebound that was associated with persisting disorganization symptoms as well as impairments in cognition and role function. Patients also showed greater task-related reductions in overall beta burst rate and showed greater, more extensive, beta burst-related blood oxygen level-dependent activation.Our evidence supports a model in which beta bursts reactivate latently maintained sensorimotor information and are dysregulated and inefficient in psychosis. We propose that abnormalities in the mechanisms by which beta bursts coordinate reactivation of contextually appropriate content can manifest as disorganization, working memory deficits, and inaccurate forward models and may underlie a core deficit associated with persisting symptoms and impairment." @default.
- W3094965993 created "2020-11-09" @default.
- W3094965993 creator A5003601817 @default.
- W3094965993 creator A5013094782 @default.
- W3094965993 creator A5021933478 @default.
- W3094965993 creator A5036975863 @default.
- W3094965993 creator A5064499319 @default.
- W3094965993 creator A5069145771 @default.
- W3094965993 creator A5084364544 @default.
- W3094965993 creator A5084803143 @default.
- W3094965993 creator A5086224910 @default.
- W3094965993 creator A5087349166 @default.
- W3094965993 date "2020-11-01" @default.
- W3094965993 modified "2023-09-24" @default.
- W3094965993 title "Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study" @default.
- W3094965993 cites W126907670 @default.
- W3094965993 cites W1509285273 @default.
- W3094965993 cites W1760829075 @default.
- W3094965993 cites W1779974355 @default.
- W3094965993 cites W1970741301 @default.
- W3094965993 cites W1983637134 @default.
- W3094965993 cites W1986346525 @default.
- W3094965993 cites W2019465651 @default.
- W3094965993 cites W2037807133 @default.
- W3094965993 cites W2046429124 @default.
- W3094965993 cites W2046716239 @default.
- W3094965993 cites W2053214069 @default.
- W3094965993 cites W2056641564 @default.
- W3094965993 cites W2063294564 @default.
- W3094965993 cites W2063473805 @default.
- W3094965993 cites W2067941370 @default.
- W3094965993 cites W2078533008 @default.
- W3094965993 cites W2099240715 @default.
- W3094965993 cites W2112023200 @default.
- W3094965993 cites W2116308679 @default.
- W3094965993 cites W2116658855 @default.
- W3094965993 cites W2119981748 @default.
- W3094965993 cites W2129022947 @default.
- W3094965993 cites W2133947591 @default.
- W3094965993 cites W2135495772 @default.
- W3094965993 cites W2143895814 @default.
- W3094965993 cites W2153394220 @default.
- W3094965993 cites W2156025382 @default.
- W3094965993 cites W2160939822 @default.
- W3094965993 cites W2162482297 @default.
- W3094965993 cites W2163200475 @default.
- W3094965993 cites W2167121714 @default.
- W3094965993 cites W21769058 @default.
- W3094965993 cites W2229256208 @default.
- W3094965993 cites W2270360904 @default.
- W3094965993 cites W2290843969 @default.
- W3094965993 cites W2297363866 @default.
- W3094965993 cites W2442993305 @default.
- W3094965993 cites W245658 @default.
- W3094965993 cites W2468463735 @default.
- W3094965993 cites W2498492890 @default.
- W3094965993 cites W2504479060 @default.
- W3094965993 cites W2546687266 @default.
- W3094965993 cites W2603262402 @default.
- W3094965993 cites W2737825378 @default.
- W3094965993 cites W2767814366 @default.
- W3094965993 cites W2770174404 @default.
- W3094965993 cites W2805339558 @default.
- W3094965993 cites W2813530246 @default.
- W3094965993 cites W2891729553 @default.
- W3094965993 cites W2901276374 @default.
- W3094965993 cites W2949486593 @default.
- W3094965993 cites W2969337627 @default.
- W3094965993 cites W2973007151 @default.
- W3094965993 cites W2985388820 @default.
- W3094965993 cites W3026969764 @default.
- W3094965993 doi "https://doi.org/10.1016/j.bpsc.2020.10.018" @default.
- W3094965993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33495122" @default.
- W3094965993 hasPublicationYear "2020" @default.
- W3094965993 type Work @default.
- W3094965993 sameAs 3094965993 @default.
- W3094965993 citedByCount "4" @default.
- W3094965993 countsByYear W30949659932021 @default.
- W3094965993 countsByYear W30949659932022 @default.
- W3094965993 crossrefType "journal-article" @default.
- W3094965993 hasAuthorship W3094965993A5003601817 @default.
- W3094965993 hasAuthorship W3094965993A5013094782 @default.
- W3094965993 hasAuthorship W3094965993A5021933478 @default.
- W3094965993 hasAuthorship W3094965993A5036975863 @default.
- W3094965993 hasAuthorship W3094965993A5064499319 @default.
- W3094965993 hasAuthorship W3094965993A5069145771 @default.
- W3094965993 hasAuthorship W3094965993A5084364544 @default.
- W3094965993 hasAuthorship W3094965993A5084803143 @default.
- W3094965993 hasAuthorship W3094965993A5086224910 @default.
- W3094965993 hasAuthorship W3094965993A5087349166 @default.
- W3094965993 hasBestOaLocation W30949659931 @default.
- W3094965993 hasConcept C118552586 @default.
- W3094965993 hasConcept C126838900 @default.
- W3094965993 hasConcept C143409427 @default.
- W3094965993 hasConcept C15744967 @default.
- W3094965993 hasConcept C169760540 @default.
- W3094965993 hasConcept C169900460 @default.
- W3094965993 hasConcept C182752723 @default.
- W3094965993 hasConcept C199360897 @default.
- W3094965993 hasConcept C21963081 @default.