Matches in SemOpenAlex for { <https://semopenalex.org/work/W3095043673> ?p ?o ?g. }
- W3095043673 endingPage "2601" @default.
- W3095043673 startingPage "2591" @default.
- W3095043673 abstract "The association between extracellular volume (ECV) measured by computed tomography angiography (CTA) and clinical outcomes was evaluated in low-flow low-gradient (LFLG) aortic stenosis (AS) patients undergoing transcatheter aortic valve replacement (TAVR).Patients with LFLG AS comprise a high-risk group with respect to clinical outcomes. Although ECV, a marker of myocardial fibrosis, is traditionally measured with cardiac magnetic resonance, it can also be measured using cardiac CTA. The authors hypothesized that in LFLG AS, increased ECV may be associated with adverse clinical outcomes.In 150 LFLG patients with AS who underwent TAVR, ECV was quantified using pre-TAVR CTA. Echocardiographic and clinical information including all-cause death and heart failure rehospitalization (HFH) was obtained from electronic medical records. A Cox proportional hazards model was used to evaluate the association between ECV and death+HFH.During a median follow-up of 13.9 months (range 0.07 to 28.9 months), there were 31 death+HFH events (21%). Patients who experienced death+HFH had a greater median Society of Thoracic Surgery score (9.9 vs. 4.7; p < 0.01), lower left ventricular ejection fraction (42.3 ± 20.2% vs. 52.7 ± 17.2%; p < 0.01), lower mean transvalvular gradient (24.9 ± 8.9 mm Hg vs. 28.1 ± 7.3 mm Hg; p = 0.04) and increased mean ECV (35.5 ± 9.6% vs. 29.9 ± 8.2%; p < 0.01) compared with patients who did not experience death+HFH. In a multivariable Cox proportional hazards model, increase in ECV was associated with increase in death+HFH, (hazard ratio per 1% increase: 1.04, 95% confidence interval: 1.01 to 1.09; p < 0.01).In patients with LFLG AS, CTA measured increase in ECV is associated with increased risk of adverse clinical outcomes post-TAVR and may thus serve as a useful noninvasive marker for prognostication." @default.
- W3095043673 created "2020-11-09" @default.
- W3095043673 creator A5002198623 @default.
- W3095043673 creator A5011222041 @default.
- W3095043673 creator A5028749992 @default.
- W3095043673 creator A5040204150 @default.
- W3095043673 creator A5041497560 @default.
- W3095043673 creator A5041612303 @default.
- W3095043673 creator A5044531608 @default.
- W3095043673 creator A5044968211 @default.
- W3095043673 creator A5046039187 @default.
- W3095043673 creator A5052713249 @default.
- W3095043673 creator A5055511044 @default.
- W3095043673 creator A5060741619 @default.
- W3095043673 creator A5061914662 @default.
- W3095043673 creator A5062520509 @default.
- W3095043673 creator A5066563877 @default.
- W3095043673 creator A5076977377 @default.
- W3095043673 creator A5081792767 @default.
- W3095043673 creator A5086264921 @default.
- W3095043673 date "2020-12-01" @default.
- W3095043673 modified "2023-10-06" @default.
- W3095043673 title "Prognostic Value of Computed Tomography–Derived Extracellular Volume in TAVR Patients With Low-Flow Low-Gradient Aortic Stenosis" @default.
- W3095043673 cites W155024021 @default.
- W3095043673 cites W1743552125 @default.
- W3095043673 cites W195414628 @default.
- W3095043673 cites W1967762499 @default.
- W3095043673 cites W2002140031 @default.
- W3095043673 cites W2010890329 @default.
- W3095043673 cites W2024799561 @default.
- W3095043673 cites W2025383517 @default.
- W3095043673 cites W2029182044 @default.
- W3095043673 cites W2065582050 @default.
- W3095043673 cites W2085786241 @default.
- W3095043673 cites W2111367427 @default.
- W3095043673 cites W2113258585 @default.
- W3095043673 cites W2120225238 @default.
- W3095043673 cites W2124624517 @default.
- W3095043673 cites W2125833000 @default.
- W3095043673 cites W2125878575 @default.
- W3095043673 cites W2153574451 @default.
- W3095043673 cites W2165159075 @default.
- W3095043673 cites W2166064988 @default.
- W3095043673 cites W2190011087 @default.
- W3095043673 cites W2321827692 @default.
- W3095043673 cites W2567057146 @default.
- W3095043673 cites W2586852067 @default.
- W3095043673 cites W2600959608 @default.
- W3095043673 cites W2737509635 @default.
- W3095043673 cites W2740843109 @default.
- W3095043673 cites W2751630023 @default.
- W3095043673 cites W2769228423 @default.
- W3095043673 cites W2774186101 @default.
- W3095043673 cites W2787819053 @default.
- W3095043673 cites W2792450684 @default.
- W3095043673 cites W2792844680 @default.
- W3095043673 cites W2793001044 @default.
- W3095043673 cites W2795216925 @default.
- W3095043673 cites W2808110229 @default.
- W3095043673 cites W2883655295 @default.
- W3095043673 cites W2888458678 @default.
- W3095043673 cites W2911906141 @default.
- W3095043673 cites W2948062384 @default.
- W3095043673 cites W3000710027 @default.
- W3095043673 cites W33235005 @default.
- W3095043673 cites W4293496224 @default.
- W3095043673 cites W4296167083 @default.
- W3095043673 cites W68457931 @default.
- W3095043673 cites W884285372 @default.
- W3095043673 cites W949094399 @default.
- W3095043673 doi "https://doi.org/10.1016/j.jcmg.2020.07.045" @default.
- W3095043673 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7850162" @default.
- W3095043673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33129731" @default.
- W3095043673 hasPublicationYear "2020" @default.
- W3095043673 type Work @default.
- W3095043673 sameAs 3095043673 @default.
- W3095043673 citedByCount "16" @default.
- W3095043673 countsByYear W30950436732020 @default.
- W3095043673 countsByYear W30950436732021 @default.
- W3095043673 countsByYear W30950436732022 @default.
- W3095043673 countsByYear W30950436732023 @default.
- W3095043673 crossrefType "journal-article" @default.
- W3095043673 hasAuthorship W3095043673A5002198623 @default.
- W3095043673 hasAuthorship W3095043673A5011222041 @default.
- W3095043673 hasAuthorship W3095043673A5028749992 @default.
- W3095043673 hasAuthorship W3095043673A5040204150 @default.
- W3095043673 hasAuthorship W3095043673A5041497560 @default.
- W3095043673 hasAuthorship W3095043673A5041612303 @default.
- W3095043673 hasAuthorship W3095043673A5044531608 @default.
- W3095043673 hasAuthorship W3095043673A5044968211 @default.
- W3095043673 hasAuthorship W3095043673A5046039187 @default.
- W3095043673 hasAuthorship W3095043673A5052713249 @default.
- W3095043673 hasAuthorship W3095043673A5055511044 @default.
- W3095043673 hasAuthorship W3095043673A5060741619 @default.
- W3095043673 hasAuthorship W3095043673A5061914662 @default.
- W3095043673 hasAuthorship W3095043673A5062520509 @default.
- W3095043673 hasAuthorship W3095043673A5066563877 @default.
- W3095043673 hasAuthorship W3095043673A5076977377 @default.