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- W3095270241 endingPage "466" @default.
- W3095270241 startingPage "449" @default.
- W3095270241 abstract "At the heart of the transcription process is the specific interaction between transcription factors (TFs) and their target DNA sequences. Decades of molecular biology research have led to unprecedented insights into how TFs access the genome to regulate transcription. In the last 20 years, advances in microscopy have enabled scientists to add imaging as a powerful tool in probing two specific aspects of TF–DNA interactions: structure and dynamics. In this review, we examine how applications of diverse imaging technologies can provide structural and dynamic information that complements insights gained from molecular biology assays. As a case study, we discuss how applications of advanced imaging techniques have reshaped our understanding of TF behavior across the cell cycle, leading to a rethinking in the field of mitotic bookmarking." @default.
- W3095270241 created "2020-11-09" @default.
- W3095270241 creator A5025758099 @default.
- W3095270241 creator A5074575801 @default.
- W3095270241 creator A5077805337 @default.
- W3095270241 creator A5085167787 @default.
- W3095270241 date "2021-04-01" @default.
- W3095270241 modified "2023-10-12" @default.
- W3095270241 title "Advances in visualizing transcription factor – DNA interactions" @default.
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