FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3095795983> ?p ?o ?g. }

• W3095795983 endingPage "250" @default.
• W3095795983 startingPage "240" @default.
• W3095795983 abstract "Growing evidence indicates the prognostic importance of the crosstalk between cancer cells and stroma through the induction of epithelial-mesenchymal transition (EMT). This study aimed to clarify the prognostic value of evaluating primary tumor histology with the anatomical extent of disease in patients with colorectal liver metastasis (CRLM).Prognostic analyses were performed in 411 CRLM patients who underwent hepatectomy at two institutions. Tumors were graded into one of three histological categories based on integrated assessment of EMT-associated histology (HistologyEMT) in primary tumors, i.e., poorly differentiated clusters (PDCs) and desmoplastic reaction (DR).A prognostic grouping system for the anatomical extent of disease (N stage, liver metastasis number and size, and extrahepatic disease; Gradeanatomical) stratified patients into three groups with different five-year relapse-free survival (RFS) rates after hepatectomy: A, 31% (191 patients); B, 15% (124 patients); and C, 6% (96 patients; P < 0.0001). HistologyEMT (A, G1 PDC and mature-type DR; C, G3 PDC and immature-type DR; and B, others) identified 49, 120, and 242 patients with 46%, 5%, and 22% five-year RFS, respectively (P < 0.0001). Among prognostic factors, the Akaike information criterion was most favorable in Gradeanatomical, followed by HistologyEMT. Multivariate analysis demonstrated that these two factors independently impacted RFS; two-year RFS after hepatectomy in different patient groups had a wide range (10%-76%).Histological assessment of dedifferentiation and the stromal environment of primary tumors contributed to effective risk stratification of early relapse after hepatectomy, which could be useful to determine clinical management for CRLM patients." @default.
• W3095795983 created "2020-11-09" @default.
• W3095795983 creator A5017324529 @default.
• W3095795983 creator A5021359572 @default.
• W3095795983 creator A5028074573 @default.
• W3095795983 creator A5038578704 @default.
• W3095795983 creator A5042800905 @default.
• W3095795983 creator A5048365478 @default.
• W3095795983 creator A5051592475 @default.
• W3095795983 creator A5054771200 @default.
• W3095795983 creator A5075220614 @default.
• W3095795983 creator A5077662682 @default.
• W3095795983 creator A5079609151 @default.
• W3095795983 creator A5083177175 @default.
• W3095795983 date "2020-01-01" @default.
• W3095795983 modified "2023-09-25" @default.
• W3095795983 title "Primary Tumor Histology Affects Oncological Outcomes Independently of the Anatomical Extent of Disease in Colorectal Liver Metastasis" @default.
• W3095795983 cites W1480706413 @default.
• W3095795983 cites W1765193236 @default.
• W3095795983 cites W1963562976 @default.
• W3095795983 cites W1964416791 @default.
• W3095795983 cites W1975218692 @default.
• W3095795983 cites W1975824954 @default.
• W3095795983 cites W1989054416 @default.
• W3095795983 cites W1990423062 @default.
• W3095795983 cites W2003398293 @default.
• W3095795983 cites W2018456625 @default.
• W3095795983 cites W2045679492 @default.
• W3095795983 cites W2051477353 @default.
• W3095795983 cites W2062809449 @default.
• W3095795983 cites W2071823746 @default.
• W3095795983 cites W2076116834 @default.
• W3095795983 cites W2084470612 @default.
• W3095795983 cites W2097755600 @default.
• W3095795983 cites W2117692326 @default.
• W3095795983 cites W2123242217 @default.
• W3095795983 cites W2138235363 @default.
• W3095795983 cites W2170866914 @default.
• W3095795983 cites W2324682341 @default.
• W3095795983 cites W2329877110 @default.
• W3095795983 doi "https://doi.org/10.31662/jmaj.2018-0004" @default.
• W3095795983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7590386" @default.
• W3095795983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33150258" @default.
• W3095795983 hasPublicationYear "2020" @default.
• W3095795983 type Work @default.
• W3095795983 sameAs 3095795983 @default.
• W3095795983 citedByCount "4" @default.
• W3095795983 countsByYear W30957959832022 @default.
• W3095795983 countsByYear W30957959832023 @default.
• W3095795983 crossrefType "journal-article" @default.
• W3095795983 hasAuthorship W3095795983A5017324529 @default.
• W3095795983 hasAuthorship W3095795983A5021359572 @default.
• W3095795983 hasAuthorship W3095795983A5028074573 @default.
• W3095795983 hasAuthorship W3095795983A5038578704 @default.
• W3095795983 hasAuthorship W3095795983A5042800905 @default.
• W3095795983 hasAuthorship W3095795983A5048365478 @default.
• W3095795983 hasAuthorship W3095795983A5051592475 @default.
• W3095795983 hasAuthorship W3095795983A5054771200 @default.
• W3095795983 hasAuthorship W3095795983A5075220614 @default.
• W3095795983 hasAuthorship W3095795983A5077662682 @default.
• W3095795983 hasAuthorship W3095795983A5079609151 @default.
• W3095795983 hasAuthorship W3095795983A5083177175 @default.
• W3095795983 hasBestOaLocation W30957959831 @default.
• W3095795983 hasConcept C121608353 @default.
• W3095795983 hasConcept C126322002 @default.
• W3095795983 hasConcept C141071460 @default.
• W3095795983 hasConcept C142724271 @default.
• W3095795983 hasConcept C143998085 @default.
• W3095795983 hasConcept C146357865 @default.
• W3095795983 hasConcept C151730666 @default.
• W3095795983 hasConcept C159110652 @default.
• W3095795983 hasConcept C16930146 @default.
• W3095795983 hasConcept C204232928 @default.
• W3095795983 hasConcept C2776909242 @default.
• W3095795983 hasConcept C2779013556 @default.
• W3095795983 hasConcept C2779134260 @default.
• W3095795983 hasConcept C2780283643 @default.
• W3095795983 hasConcept C38180746 @default.
• W3095795983 hasConcept C52124034 @default.
• W3095795983 hasConcept C526805850 @default.
• W3095795983 hasConcept C57742111 @default.
• W3095795983 hasConcept C71924100 @default.
• W3095795983 hasConcept C86803240 @default.
• W3095795983 hasConcept C90924648 @default.
• W3095795983 hasConceptScore W3095795983C121608353 @default.
• W3095795983 hasConceptScore W3095795983C126322002 @default.
• W3095795983 hasConceptScore W3095795983C141071460 @default.
• W3095795983 hasConceptScore W3095795983C142724271 @default.
• W3095795983 hasConceptScore W3095795983C143998085 @default.
• W3095795983 hasConceptScore W3095795983C146357865 @default.
• W3095795983 hasConceptScore W3095795983C151730666 @default.
• W3095795983 hasConceptScore W3095795983C159110652 @default.
• W3095795983 hasConceptScore W3095795983C16930146 @default.
• W3095795983 hasConceptScore W3095795983C204232928 @default.
• W3095795983 hasConceptScore W3095795983C2776909242 @default.
• W3095795983 hasConceptScore W3095795983C2779013556 @default.
• W3095795983 hasConceptScore W3095795983C2779134260 @default.
• W3095795983 hasConceptScore W3095795983C2780283643 @default.

• next