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- W3095800344 startingPage "115831" @default.
- W3095800344 abstract "Acrolein, a highly reactive α,β-unsaturated aldehyde, is a compound to which humans are exposed in many different situations and often causes various human diseases. This paper summarizes the reports over the past twenty-five years regarding disease-associated acrolein detected in clinical patients and the role acrolein plays in various diseases. In several diseases, it was found that the increased acrolein acts as a pathogenetic factor. Thus, we propose the utility of over-produced acrolein as a substrate for a promising therapeutic or diagnostic method applicable to a wide range of diseases based on an in vivo synthetic chemistry strategy." @default.
- W3095800344 created "2020-11-09" @default.
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- W3095800344 date "2020-12-01" @default.
- W3095800344 modified "2023-10-16" @default.
- W3095800344 title "Disease-associated acrolein: A possible diagnostic and therapeutic substrate for in vivo synthetic chemistry" @default.
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- W3095800344 doi "https://doi.org/10.1016/j.bmc.2020.115831" @default.
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