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- W3095986402 abstract "Parapoxvirus (PPV) has been identified in some mammals and poses a great threat to both the livestock production and public health. However, the prevalence and evolution of this virus are still not fully understood. Here, we performed an in silico analysis to investigate the genomic features and evolution of PPVs. We noticed that although there were significant differences of GC contents between orf virus (ORFV) and other three species of PPVs, all PPVs showed almost identical nucleotide bias, that is GC richness. The structural analysis of PPV genomes showed the divergence of different PPV species, which may be due to the specific adaptation to their natural hosts. Additionally, we estimated the phylogenetic diversity of seven different genes of PPV. According to all available sequences, our results suggested that during 2010–2018, ORFV was the dominant virus species under the selective pressure of the optimal gene patterns. Furthermore, we found the substitution rates ranged from 3.56 × 10−5 to 4.21 × 10−4 in different PPV segments, and the PPV VIR gene evolved at the highest substitution rate. In these seven protein-coding regions, purifying selection was the major evolutionary pressure, while the GIF and VIR genes suffered the greatest positive selection pressure. These results may provide useful knowledge on the virus genetic evolution from a new perspective which could help to create prevention and control strategies." @default.
- W3095986402 created "2020-11-09" @default.
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- W3095986402 date "2020-10-27" @default.
- W3095986402 modified "2023-10-02" @default.
- W3095986402 title "Genomic Features and Evolution of the Parapoxvirus during the Past Two Decades" @default.
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- W3095986402 cites W1605177007 @default.
- W3095986402 cites W1638753340 @default.
- W3095986402 cites W1969042907 @default.
- W3095986402 cites W1979587026 @default.
- W3095986402 cites W1981183703 @default.
- W3095986402 cites W1998897012 @default.
- W3095986402 cites W1999752340 @default.
- W3095986402 cites W2007780832 @default.
- W3095986402 cites W2009332226 @default.
- W3095986402 cites W2011697915 @default.
- W3095986402 cites W2018715097 @default.
- W3095986402 cites W2020350008 @default.
- W3095986402 cites W2021595553 @default.
- W3095986402 cites W2023119078 @default.
- W3095986402 cites W2023276162 @default.
- W3095986402 cites W2024498172 @default.
- W3095986402 cites W2024729193 @default.
- W3095986402 cites W2025541210 @default.
- W3095986402 cites W2026062398 @default.
- W3095986402 cites W2029325157 @default.
- W3095986402 cites W2033588475 @default.
- W3095986402 cites W2035199058 @default.
- W3095986402 cites W2037179882 @default.
- W3095986402 cites W2057243038 @default.
- W3095986402 cites W2066149369 @default.
- W3095986402 cites W2066726866 @default.
- W3095986402 cites W2075665110 @default.
- W3095986402 cites W2078054905 @default.
- W3095986402 cites W2080288119 @default.
- W3095986402 cites W2081255681 @default.
- W3095986402 cites W2081339313 @default.
- W3095986402 cites W2081747108 @default.
- W3095986402 cites W2081751502 @default.
- W3095986402 cites W2082317596 @default.
- W3095986402 cites W2087339944 @default.
- W3095986402 cites W2091184587 @default.
- W3095986402 cites W2092464136 @default.
- W3095986402 cites W2093260830 @default.
- W3095986402 cites W2098037167 @default.
- W3095986402 cites W2098075719 @default.
- W3095986402 cites W2108396590 @default.
- W3095986402 cites W2111075029 @default.
- W3095986402 cites W2118985822 @default.
- W3095986402 cites W2119047742 @default.
- W3095986402 cites W2122419499 @default.
- W3095986402 cites W2126122346 @default.
- W3095986402 cites W2132632499 @default.
- W3095986402 cites W2132926880 @default.
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- W3095986402 cites W2145651741 @default.
- W3095986402 cites W2146602601 @default.
- W3095986402 cites W2151868151 @default.
- W3095986402 cites W2152786092 @default.
- W3095986402 cites W2162500369 @default.
- W3095986402 cites W2164582219 @default.
- W3095986402 cites W2167680216 @default.
- W3095986402 cites W2306871442 @default.
- W3095986402 cites W2322358787 @default.
- W3095986402 cites W2619313640 @default.
- W3095986402 cites W2746251373 @default.
- W3095986402 cites W2749476508 @default.
- W3095986402 cites W2765549458 @default.
- W3095986402 cites W2783973409 @default.
- W3095986402 cites W2790493421 @default.
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- W3095986402 cites W2802805146 @default.
- W3095986402 cites W2809960702 @default.
- W3095986402 cites W2884156006 @default.
- W3095986402 cites W2914603165 @default.
- W3095986402 cites W2937523700 @default.
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- W3095986402 doi "https://doi.org/10.3390/pathogens9110888" @default.
- W3095986402 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7694016" @default.
- W3095986402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33120928" @default.
- W3095986402 hasPublicationYear "2020" @default.
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