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- W3096084039 endingPage "5118" @default.
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- W3096084039 abstract "Hypercholesterolemia is a major cause of atherosclerosis development and premature cardiovascular disease (CVD). It leads to inflammation, which further accelerates atherosclerosis progression. Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated serum LDL-c from birth, due to a disease-causing variant in one of the causative genes (LDLR, APOB, PCSK9). In polygenic hypercholesterolemia (PH), the disease-causing genetic variant is absent; it is likely the cumulative result of multiple single nucleotide polymorphisms in LDL metabolism-related genes and other factors, such as lifestyle and environment. In high risk groups, such as patients with FH, an effective primary prevention of CVD must begin in childhood. High-sensitivity C-reactive protein (hsCRP) and carotid intima media thickness (cIMT) are two potential minimally invasive correlates of inflammation and subclinical atherosclerosis progression. hsCRP and cIMT have been shown to be significantly increased in patients with FH and PH relative to healthy controls, with some studies yielding conflicting results. In this review, we aim to summarize current knowledge and recent findings regarding the applicability of hsCRP and cIMT as markers of low-grade inflammation and subclinical atherosclerosis, focusing especially on children and adolescents with hypercholesterolemia." @default.
- W3096084039 created "2020-11-09" @default.
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- W3096084039 date "2020-11-04" @default.
- W3096084039 modified "2023-09-28" @default.
- W3096084039 title "High-Sensitivity C-Reactive Protein and Carotid Intima Media Thickness as Markers of Subclinical Inflammation and Atherosclerosis in Pediatric Patients with Hypercholesterolemia" @default.
- W3096084039 cites W115717089 @default.
- W3096084039 cites W1751311429 @default.
- W3096084039 cites W1803918690 @default.
- W3096084039 cites W1812416290 @default.
- W3096084039 cites W1972483153 @default.
- W3096084039 cites W1980550449 @default.
- W3096084039 cites W1981212842 @default.
- W3096084039 cites W1996536247 @default.
- W3096084039 cites W1999946411 @default.
- W3096084039 cites W2002349652 @default.
- W3096084039 cites W2017499355 @default.
- W3096084039 cites W2022436698 @default.
- W3096084039 cites W2025689354 @default.
- W3096084039 cites W2031350146 @default.
- W3096084039 cites W2032329963 @default.
- W3096084039 cites W2033796658 @default.
- W3096084039 cites W2058610272 @default.
- W3096084039 cites W2059249399 @default.
- W3096084039 cites W2072751592 @default.
- W3096084039 cites W2092043066 @default.
- W3096084039 cites W2093631945 @default.
- W3096084039 cites W2099163669 @default.
- W3096084039 cites W2100142648 @default.
- W3096084039 cites W2104299102 @default.
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- W3096084039 cites W2171440286 @default.
- W3096084039 cites W2204429101 @default.
- W3096084039 cites W2224203687 @default.
- W3096084039 cites W2277290778 @default.
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- W3096084039 cites W2285387094 @default.
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- W3096084039 cites W2315094834 @default.
- W3096084039 cites W2342816298 @default.
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- W3096084039 doi "https://doi.org/10.3390/molecules25215118" @default.
- W3096084039 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7663751" @default.
- W3096084039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33158028" @default.
- W3096084039 hasPublicationYear "2020" @default.
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