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- W3096132007 abstract "An in vivo experimental study was conducted to evaluate the effect of a plasma-treated aloe vera slice on cutaneous acute wound healing using a small animal model. A nonequilibrium atmospheric plasma pressure jet (N-APPJ) was developed. Aloe vera slices with thicknesses of approximately 2 mm were treated by N-APPJ at distances of 5 mm, 10 mm, and 20 mm before application. Possible reactive species on the surfaces of the plasma-treated aloe vera slices were chemically identified. Forty-five male Balb/c mice, aged 7−8 weeks, were classified into 5 groups: control (C), aloe vera slice alone (Av), plasma-treated aloe vera slice at 5-mm distance (PTAv-5), plasma-treated aloe vera slice at 10-mm distance (PTAv-10), and plasma-treated aloe vera slice at 20-mm distance (PAV-20). Wounds were observed for 14 days. Histological evaluation using general staining for re-epithelialization was also conducted. The dropped-water method was able to identify surfatic RONS. Additionally, this investigation revealed that sizes of wound areas in groups containing an aloe vera slice, from days 2 to 14, were significantly smaller compared with the control group. During the proliferative phase, wound size in PTAv-20 was smaller than that in both PTAv-5 and PTAv-10. From days 4 to 7, wound size in PTAv-20 was slightly smaller than that in Av; however, wound size in PTAv-5 and PTAv-10 was greater than that in PTAv-20. On day 7, re-epithelialization percentages in Av and PTAv-20 were significantly higher than in C. It was concluded that plasma-treated aloe vera has the ability to influence the proliferative phase of wound healing." @default.
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- W3096132007 date "2020-01-01" @default.
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- W3096132007 title "Plasma Jet-Treated Lidah Buaya (Aloe Vera) Influences Proliferative-Phase Wound Healing" @default.
- W3096132007 doi "https://doi.org/10.1615/plasmamed.2020036388" @default.
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