Matches in SemOpenAlex for { <https://semopenalex.org/work/W3096192534> ?p ?o ?g. }
- W3096192534 endingPage "e003378" @default.
- W3096192534 startingPage "e003378" @default.
- W3096192534 abstract "Introduction In many malaria-endemic countries, the private retail sector is a major source of antimalarial drugs. However, the rarity of malaria diagnostic testing in the retail sector leads to overuse of the first-line class of antimalarial drugs known as artemisinin-combination therapies (ACTs). The goal of this study was to identify the combination of malaria rapid diagnostic test (RDT) and ACT subsidies that maximises the proportion of clients seeking care in a retail outlet that choose to purchase an RDT (RDT uptake) and use ACTs appropriately. Methods 842 clients seeking care in 12 select retail outlets in western Kenya were recruited and randomised into 4 arms of different combinations of ACT and RDT subsidies, with ACT subsidies conditional on a positive RDT. The outcomes were RDT uptake (primary) and appropriate and targeted ACT use (secondary). Participants’ familiarity with RDTs and their confidence in test results were also evaluated. Results RDT uptake was high (over 96%) across the study arms. Testing uptake was 1.025 times higher (98% CI 1.002 to 1.049) in the RDT subsidised arms than in the unsubsidised groups. Over 98% of clients were aware of malaria testing, but only 35% had a previous experience with RDTs. Nonetheless, confidence in the accuracy of RDTs was high. We found high levels of appropriate use and targeting of ACTs, with 86% of RDT positives taking an ACT, and 93.4% of RDT negatives not taking an ACT. The conditional ACT subsidy did not affect the RDT test purchasing behaviour (risk ratio: 0.994; 98% CI 0.979 to 1.009). Conclusion Test dependent ACT subsidies may contribute to ACT targeting. However, in this context, high confidence in the accuracy of RDTs and reliable supplies of RDTs and ACTs likely played a greater role in testing uptake and adherence to test results." @default.
- W3096192534 created "2020-11-09" @default.
- W3096192534 creator A5006610331 @default.
- W3096192534 creator A5019044219 @default.
- W3096192534 creator A5021585564 @default.
- W3096192534 creator A5022882515 @default.
- W3096192534 creator A5063204758 @default.
- W3096192534 creator A5083314461 @default.
- W3096192534 creator A5083697699 @default.
- W3096192534 date "2020-11-01" @default.
- W3096192534 modified "2023-10-02" @default.
- W3096192534 title "Subsidise the test, the treatment or both? Results of an individually randomised controlled trial of the management of suspected malaria fevers in the retail sector in western Kenya" @default.
- W3096192534 cites W1552087785 @default.
- W3096192534 cites W1552139595 @default.
- W3096192534 cites W1822978939 @default.
- W3096192534 cites W1972686260 @default.
- W3096192534 cites W1992487749 @default.
- W3096192534 cites W1997729157 @default.
- W3096192534 cites W2018733616 @default.
- W3096192534 cites W2026723594 @default.
- W3096192534 cites W2087942791 @default.
- W3096192534 cites W2089714452 @default.
- W3096192534 cites W2090339074 @default.
- W3096192534 cites W2099035607 @default.
- W3096192534 cites W2103839285 @default.
- W3096192534 cites W2118905339 @default.
- W3096192534 cites W2121524600 @default.
- W3096192534 cites W2123644306 @default.
- W3096192534 cites W2132613714 @default.
- W3096192534 cites W2133901317 @default.
- W3096192534 cites W2138298900 @default.
- W3096192534 cites W2144029319 @default.
- W3096192534 cites W2167208852 @default.
- W3096192534 cites W2301483619 @default.
- W3096192534 cites W2341282147 @default.
- W3096192534 cites W2471658003 @default.
- W3096192534 cites W2525513471 @default.
- W3096192534 cites W2530569707 @default.
- W3096192534 cites W2565054976 @default.
- W3096192534 cites W2577639839 @default.
- W3096192534 cites W2592598035 @default.
- W3096192534 cites W2593102090 @default.
- W3096192534 cites W2615915024 @default.
- W3096192534 cites W2742398833 @default.
- W3096192534 cites W2766972580 @default.
- W3096192534 cites W2781088666 @default.
- W3096192534 cites W2951758813 @default.
- W3096192534 cites W3009174729 @default.
- W3096192534 cites W4253532774 @default.
- W3096192534 doi "https://doi.org/10.1136/bmjgh-2020-003378" @default.
- W3096192534 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7640502" @default.
- W3096192534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33148541" @default.
- W3096192534 hasPublicationYear "2020" @default.
- W3096192534 type Work @default.
- W3096192534 sameAs 3096192534 @default.
- W3096192534 citedByCount "7" @default.
- W3096192534 countsByYear W30961925342021 @default.
- W3096192534 countsByYear W30961925342022 @default.
- W3096192534 countsByYear W30961925342023 @default.
- W3096192534 crossrefType "journal-article" @default.
- W3096192534 hasAuthorship W3096192534A5006610331 @default.
- W3096192534 hasAuthorship W3096192534A5019044219 @default.
- W3096192534 hasAuthorship W3096192534A5021585564 @default.
- W3096192534 hasAuthorship W3096192534A5022882515 @default.
- W3096192534 hasAuthorship W3096192534A5063204758 @default.
- W3096192534 hasAuthorship W3096192534A5083314461 @default.
- W3096192534 hasAuthorship W3096192534A5083697699 @default.
- W3096192534 hasBestOaLocation W30961925341 @default.
- W3096192534 hasConcept C144133560 @default.
- W3096192534 hasConcept C151730666 @default.
- W3096192534 hasConcept C162324750 @default.
- W3096192534 hasConcept C203014093 @default.
- W3096192534 hasConcept C2776120307 @default.
- W3096192534 hasConcept C2777267654 @default.
- W3096192534 hasConcept C2778048844 @default.
- W3096192534 hasConcept C2778371730 @default.
- W3096192534 hasConcept C2780261877 @default.
- W3096192534 hasConcept C34447519 @default.
- W3096192534 hasConcept C71924100 @default.
- W3096192534 hasConcept C84265765 @default.
- W3096192534 hasConcept C86803240 @default.
- W3096192534 hasConceptScore W3096192534C144133560 @default.
- W3096192534 hasConceptScore W3096192534C151730666 @default.
- W3096192534 hasConceptScore W3096192534C162324750 @default.
- W3096192534 hasConceptScore W3096192534C203014093 @default.
- W3096192534 hasConceptScore W3096192534C2776120307 @default.
- W3096192534 hasConceptScore W3096192534C2777267654 @default.
- W3096192534 hasConceptScore W3096192534C2778048844 @default.
- W3096192534 hasConceptScore W3096192534C2778371730 @default.
- W3096192534 hasConceptScore W3096192534C2780261877 @default.
- W3096192534 hasConceptScore W3096192534C34447519 @default.
- W3096192534 hasConceptScore W3096192534C71924100 @default.
- W3096192534 hasConceptScore W3096192534C84265765 @default.
- W3096192534 hasConceptScore W3096192534C86803240 @default.
- W3096192534 hasIssue "11" @default.
- W3096192534 hasLocation W30961925341 @default.
- W3096192534 hasLocation W30961925342 @default.
- W3096192534 hasOpenAccess W3096192534 @default.