FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3096233601> ?p ?o ?g. }

• W3096233601 abstract "Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune neurological disorder. Osteopontin (OPN) is a secreted multifunctional phosphorylated glycoprotein that regulates various autoimmune and inflammatory diseases, but its diagnostic and prognostic values in anti-NMDAR encephalitis patients remain elusive. This retrospective study aimed to determine the levels of OPN and related cytokines in cerebrospinal fluid (CSF) of anti-NMDAR encephalitis patients and to assess their influence on disease severity so as to evaluate their efficacy as biomarkers for diagnosis and prognosis. CSF samples from 33 anti-NMDAR encephalitis, 13 viral encephalitis, and 21 controls were collected. All CSF were tested for levels of OPN and inflammation-associated cytokines [interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF)-α] via ELISA. In addition, 15 anti-NMDAR encephalitis patients without follow-up relapse were re-examined for these four parameters 3 months later. The clinical status was evaluated by modified Rankin Scale (mRS) scores. Results showed that the CSF levels of these cytokines were increased in anti-NMDAR encephalitis patients compared to controls but not viral encephalitis patients. Their levels were decreased in remission compared with that in acute stage. Moreover, CSF OPN positively correlated with IL-6, white blood cell (WBC) counts, and C-reactive protein (CRP) levels in anti-NMDAR encephalitis patients. However, no associations were found between OPN or related cytokines and mRS scores in acute stage in anti-NMDAR encephalitis patients. Overall, CSF OPN and related cytokines were increased when anti-NMDAR encephalitis patients are in acute stage and decreased in remission, suggesting the underlying neuro-inflammatory process in this disease. However, they are not qualified with diagnostic or prognostic value." @default.
• W3096233601 created "2020-11-09" @default.
• W3096233601 creator A5000336592 @default.
• W3096233601 creator A5004742310 @default.
• W3096233601 creator A5010450016 @default.
• W3096233601 creator A5012641833 @default.
• W3096233601 creator A5017272279 @default.
• W3096233601 creator A5017811572 @default.
• W3096233601 creator A5025441749 @default.
• W3096233601 creator A5058668850 @default.
• W3096233601 creator A5076445331 @default.
• W3096233601 creator A5005574857 @default.
• W3096233601 date "2020-11-05" @default.
• W3096233601 modified "2023-10-01" @default.
• W3096233601 title "Cerebrospinal Fluid Osteopontin and Inflammation-Associated Cytokines in Patients With Anti-N-Methyl-D-Aspartate Receptor Encephalitis" @default.
• W3096233601 cites W1487260137 @default.
• W3096233601 cites W1750523482 @default.
• W3096233601 cites W1977209026 @default.
• W3096233601 cites W1987488978 @default.
• W3096233601 cites W1997940422 @default.
• W3096233601 cites W2001065481 @default.
• W3096233601 cites W2013576325 @default.
• W3096233601 cites W2016064855 @default.
• W3096233601 cites W2028195000 @default.
• W3096233601 cites W2051552021 @default.
• W3096233601 cites W2061839191 @default.
• W3096233601 cites W2062414504 @default.
• W3096233601 cites W2066911031 @default.
• W3096233601 cites W2069821412 @default.
• W3096233601 cites W2072597173 @default.
• W3096233601 cites W2084493358 @default.
• W3096233601 cites W2088059979 @default.
• W3096233601 cites W2089794703 @default.
• W3096233601 cites W2092574890 @default.
• W3096233601 cites W2096069651 @default.
• W3096233601 cites W2098001563 @default.
• W3096233601 cites W2104895892 @default.
• W3096233601 cites W2116381107 @default.
• W3096233601 cites W2117062936 @default.
• W3096233601 cites W2119508007 @default.
• W3096233601 cites W2136044852 @default.
• W3096233601 cites W2140698589 @default.
• W3096233601 cites W2159901127 @default.
• W3096233601 cites W2163022996 @default.
• W3096233601 cites W2280783985 @default.
• W3096233601 cites W2291138108 @default.
• W3096233601 cites W2520403444 @default.
• W3096233601 cites W2626951440 @default.
• W3096233601 cites W2764134495 @default.
• W3096233601 cites W2774144003 @default.
• W3096233601 cites W2905472466 @default.
• W3096233601 cites W2914547220 @default.
• W3096233601 cites W2938341288 @default.
• W3096233601 cites W2953680739 @default.
• W3096233601 cites W2960896024 @default.
• W3096233601 cites W2969827726 @default.
• W3096233601 cites W2987961312 @default.
• W3096233601 doi "https://doi.org/10.3389/fneur.2020.519692" @default.
• W3096233601 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7676223" @default.
• W3096233601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33250837" @default.
• W3096233601 hasPublicationYear "2020" @default.
• W3096233601 type Work @default.
• W3096233601 sameAs 3096233601 @default.
• W3096233601 citedByCount "6" @default.
• W3096233601 countsByYear W30962336012022 @default.
• W3096233601 countsByYear W30962336012023 @default.
• W3096233601 crossrefType "journal-article" @default.
• W3096233601 hasAuthorship W3096233601A5000336592 @default.
• W3096233601 hasAuthorship W3096233601A5004742310 @default.
• W3096233601 hasAuthorship W3096233601A5005574857 @default.
• W3096233601 hasAuthorship W3096233601A5010450016 @default.
• W3096233601 hasAuthorship W3096233601A5012641833 @default.
• W3096233601 hasAuthorship W3096233601A5017272279 @default.
• W3096233601 hasAuthorship W3096233601A5017811572 @default.
• W3096233601 hasAuthorship W3096233601A5025441749 @default.
• W3096233601 hasAuthorship W3096233601A5058668850 @default.
• W3096233601 hasAuthorship W3096233601A5076445331 @default.
• W3096233601 hasBestOaLocation W30962336011 @default.
• W3096233601 hasConcept C142724271 @default.
• W3096233601 hasConcept C164027704 @default.
• W3096233601 hasConcept C17991360 @default.
• W3096233601 hasConcept C203014093 @default.
• W3096233601 hasConcept C2522874641 @default.
• W3096233601 hasConcept C2776914184 @default.
• W3096233601 hasConcept C2779651940 @default.
• W3096233601 hasConcept C2779734145 @default.
• W3096233601 hasConcept C2780804394 @default.
• W3096233601 hasConcept C71924100 @default.
• W3096233601 hasConcept C83455156 @default.
• W3096233601 hasConceptScore W3096233601C142724271 @default.
• W3096233601 hasConceptScore W3096233601C164027704 @default.
• W3096233601 hasConceptScore W3096233601C17991360 @default.
• W3096233601 hasConceptScore W3096233601C203014093 @default.
• W3096233601 hasConceptScore W3096233601C2522874641 @default.
• W3096233601 hasConceptScore W3096233601C2776914184 @default.
• W3096233601 hasConceptScore W3096233601C2779651940 @default.
• W3096233601 hasConceptScore W3096233601C2779734145 @default.
• W3096233601 hasConceptScore W3096233601C2780804394 @default.
• W3096233601 hasConceptScore W3096233601C71924100 @default.
• W3096233601 hasConceptScore W3096233601C83455156 @default.

• next