Matches in SemOpenAlex for { <https://semopenalex.org/work/W3096259036> ?p ?o ?g. }
Showing items 1 to 49 of
49
with 100 items per page.
- W3096259036 abstract "Background The role of gold salts in the present therapy of rheumatoid arthritis (RA) remains controversial. Objectives To analyse the clinical efficacy (according to ACR response criteria) of a therapeutic protocol, that includes sodium aurothiomalate as first option DMARD in patients with recent onset RA. Methods All patients with RA (ACR diagnostic criteria) for less than two years disease duration and no previous DMARD therapy, attending our Rheumatology Units during 1998–99, have been included in a therapeutic protocol, in which the first administered DMARD was sodium aurothiomalate at a dose of 50 mg/week. According to the ACR response at 6 months (no improvement, ACR-20 or ACR-50) patients were treated with methotrexate (MTX) alone, aurothiomalate plus MTX or aurothiomalate alone, respectively. Low dose of steroids ( Results Forty seven (7M/40F) patients were included (age:54 ± 16 years; disease duration:10 ± 7 months; RF+:40(85%)). The percentages of ACR responders at 6 and 12 months were as shown at the Table 1. Twenty-four per cent of patients discontinued gold salts due to adverse events or inefficacy at 12 months. Aurothiomalate was continued in 61% of patients as monotherapy and in 15% of patients in combination with MTX. Conclusion Gold salts still have an important role in RA treatment. The use of aurothiomalate should be taken into account in the present therapeutic strategies of patients with early RA." @default.
- W3096259036 created "2020-11-09" @default.
- W3096259036 creator A5015632247 @default.
- W3096259036 creator A5034945058 @default.
- W3096259036 creator A5041596944 @default.
- W3096259036 creator A5062558600 @default.
- W3096259036 creator A5069391174 @default.
- W3096259036 creator A5072948533 @default.
- W3096259036 creator A5083463038 @default.
- W3096259036 date "2001-06-01" @default.
- W3096259036 modified "2023-09-26" @default.
- W3096259036 title "FRI0026 Therapeutic strategy with sodium aurothio- malate as first choice dmard in early rheumatoid arthritis: preliminary results" @default.
- W3096259036 doi "https://doi.org/10.1136/annrheumdis-2001.1155" @default.
- W3096259036 hasPublicationYear "2001" @default.
- W3096259036 type Work @default.
- W3096259036 sameAs 3096259036 @default.
- W3096259036 citedByCount "0" @default.
- W3096259036 crossrefType "proceedings-article" @default.
- W3096259036 hasAuthorship W3096259036A5015632247 @default.
- W3096259036 hasAuthorship W3096259036A5034945058 @default.
- W3096259036 hasAuthorship W3096259036A5041596944 @default.
- W3096259036 hasAuthorship W3096259036A5062558600 @default.
- W3096259036 hasAuthorship W3096259036A5069391174 @default.
- W3096259036 hasAuthorship W3096259036A5072948533 @default.
- W3096259036 hasAuthorship W3096259036A5083463038 @default.
- W3096259036 hasBestOaLocation W30962590361 @default.
- W3096259036 hasConcept C126322002 @default.
- W3096259036 hasConcept C197934379 @default.
- W3096259036 hasConcept C198451711 @default.
- W3096259036 hasConcept C2777575956 @default.
- W3096259036 hasConcept C2780570811 @default.
- W3096259036 hasConcept C2781059491 @default.
- W3096259036 hasConcept C71924100 @default.
- W3096259036 hasConcept C90924648 @default.
- W3096259036 hasConceptScore W3096259036C126322002 @default.
- W3096259036 hasConceptScore W3096259036C197934379 @default.
- W3096259036 hasConceptScore W3096259036C198451711 @default.
- W3096259036 hasConceptScore W3096259036C2777575956 @default.
- W3096259036 hasConceptScore W3096259036C2780570811 @default.
- W3096259036 hasConceptScore W3096259036C2781059491 @default.
- W3096259036 hasConceptScore W3096259036C71924100 @default.
- W3096259036 hasConceptScore W3096259036C90924648 @default.
- W3096259036 hasLocation W30962590361 @default.
- W3096259036 hasOpenAccess W3096259036 @default.
- W3096259036 hasPrimaryLocation W30962590361 @default.
- W3096259036 isParatext "false" @default.
- W3096259036 isRetracted "false" @default.
- W3096259036 magId "3096259036" @default.
- W3096259036 workType "article" @default.