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• W3096318206 abstract "The spectrum of uterine lesions of mesenchymal and mixed mesenchymal-epithelial type has expanded in recent years, largely due to the cumulative experience reported in larger case series, as well as the identification of recurrent gene fusions and other molecular alterations. In routine practice, the approach to most mesenchymal neoplasms encountered of the uterus starts with a judicious morphologic approach, which in many cases suffices for the diagnosis. Smooth muscle tumors predominate, most of them being benign. Distinction of conventional and variant leiomyoma types from leiomyosarcoma is important but on occasion challenging, and some lesions remain in the category of unknown malignant potential. Endometrial stromal neoplasms follow in frequency; their distinction from other mesenchymal lesions may be difficult, and molecular testing is gaining momentum as a key ancillary tool in their diagnosis. These two major categories are covered in depth here, along with other mesenchymal lesions with significant occurrence in the uterus. An emphasis is given on the differential diagnosis of each entity. The chapter also covers neoplasms with mixed mesenchymal and epithelial components (except endometrial polyp, which is presented in Chapter 9 ); of these, the most important clinically is adenosarcoma. The chapter concludes with miscellaneous lesions of histopathologic diagnostic importance." @default.
• W3096318206 created "2020-11-09" @default.
• W3096318206 creator A5014189905 @default.
• W3096318206 date "2020-01-01" @default.
• W3096318206 modified "2023-09-25" @default.
• W3096318206 title "Mesenchymal and Miscellaneous Lesions of the Uterus" @default.
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