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• W3096403948 abstract "BACKGROUND Central obesity is known to be associated with diabetes. Increasing lower extremity circumference was hypothesized in association with lower risk of diabetes. OBJECTIVE This study determined which anthropometric patterns correlates the best with pre-diabetic and diabetic status among healthy adults. DESIGN Cross-sectional study with nationwide population sampling of participants was designed. PARTICIPANTS In total, 1,358 ethnic Chinese adult participants were recruited from the Nutrition and Health Survey in Taiwan 2013-2016; the whole-body composition was measured through dual-energy X-ray absorptiometry. MAIN OUTCOME MEASURES Fat and lean mass in whole and specific parts of body among heathy Asian adults with normal glycemic, pre-diabetic, and diabetic states were measured, separately. STATISTICAL ANALYSES PERFORMED The generalized linear model was used to investigate the association between body composition (lean and fat mass) and hyperglycemic status. The reduced rank regression (RRR) was used to confirm the correlation between glycemic status and predicting factors (body composition parameters). RESULTS Trunk fat positively correlated with the fasting glucose level (r = 0.327, P < 0.001) and HbA1c (r = 0.329, P < 0.001), whereas limb fat negatively correlated with the fasting glucose level (r = -0.325, P < 0.001) and HbA1c (ρ = -0.342, P < 0.001), respectively. In RRR analyses, fasting glucose and HbA1c exhibited a high positive association on fat amount per lean mass of the trunk (factor loading = 0.5319 and 0.5599, respectively) and of android area (0.6422 and 0.6104) and a high negative association fat amount per lean mass of the legs (-0.3863 and -0.3083) and gynoid area (-0.3414 and -0.3725). CONCLUSIONS For healthy community participants, increasing trunk fat had a greater risk of hyperglycemic status. Increasing lower extremity mass may confer lower risk of diabetes." @default.
• W3096403948 created "2020-11-09" @default.
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• W3096403948 date "2020-11-04" @default.
• W3096403948 modified "2023-09-25" @default.
• W3096403948 title "Body composition patterns among normal glycemic, pre-diabetic, diabetic health Chinese adults in community: NAHSIT 2013–2016" @default.
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• W3096403948 doi "https://doi.org/10.1371/journal.pone.0241121" @default.
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