FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3096551471> ?p ?o ?g. }

• W3096551471 endingPage "321" @default.
• W3096551471 startingPage "311" @default.
• W3096551471 abstract "Methylmercury (MeHg) intoxication is associated with hypertension, hypercholesterolemia, and atherosclerosis by mechanisms that are not yet fully understood. We investigated the effects of MeHg intoxication in atherosclerosis-prone (ApoE-KO) and resistant C57BL/6 mice. Mice were submitted to carotid stenosis surgery (to induce atherosclerosis faster) and received water or MeHg solution (20 mg/L) for 15 days. Tail plethysmography was performed before and after MeHg exposure. Food and MeHg solution intakes were monitored weekly. On the 15th day, mice were submitted to intravital fluorescence microscopy of mesenteric vasculature to observe in vivo leukocyte rolling and adhesion. Results showed that despite the high hair and liver Hg concentrations in the MeHg group, food and water (or MeHg solution) consumption and liver function marker levels were similar to those in controls. MeHg exposure increased total cholesterol, the atherogenic (non-HDL) fraction and systolic and diastolic blood pressure. MeHg exposure also induced inflammation, as seen by the increased rolling and adhered leukocytes in the mesenteric vasculature. Atherosclerosis lesions were more extensive in the aorta and carotid sites of MeHg-ApoE knockout mice. Surprisingly, MeHg exposure also induced atherosclerosis lesions in C57BL/6 mice, which are resistant to atherosclerosis formation. We concluded that MeHg intoxication might represent a risk for cardiovascular diseases since it accelerates atherogenesis by exacerbating several independent risk factors." @default.
• W3096551471 created "2020-11-09" @default.
• W3096551471 creator A5008781978 @default.
• W3096551471 creator A5014426469 @default.
• W3096551471 creator A5028544162 @default.
• W3096551471 creator A5039369542 @default.
• W3096551471 creator A5051741661 @default.
• W3096551471 creator A5054156788 @default.
• W3096551471 creator A5056174606 @default.
• W3096551471 creator A5064948920 @default.
• W3096551471 creator A5072241532 @default.
• W3096551471 creator A5072762941 @default.
• W3096551471 creator A5072834025 @default.
• W3096551471 creator A5086745623 @default.
• W3096551471 date "2020-11-05" @default.
• W3096551471 modified "2023-10-16" @default.
• W3096551471 title "Oral methylmercury intoxication aggravates cardiovascular risk factors and accelerates atherosclerosis lesion development in ApoE knockout and C57BL/6 mice" @default.
• W3096551471 cites W118001903 @default.
• W3096551471 cites W1522109397 @default.
• W3096551471 cites W1970342920 @default.
• W3096551471 cites W1975723842 @default.
• W3096551471 cites W1983781936 @default.
• W3096551471 cites W1985327645 @default.
• W3096551471 cites W1987636007 @default.
• W3096551471 cites W1992980650 @default.
• W3096551471 cites W1993873300 @default.
• W3096551471 cites W2001569469 @default.
• W3096551471 cites W2002251387 @default.
• W3096551471 cites W2006689480 @default.
• W3096551471 cites W2012690683 @default.
• W3096551471 cites W2022030431 @default.
• W3096551471 cites W2026183705 @default.
• W3096551471 cites W2040330912 @default.
• W3096551471 cites W2044230655 @default.
• W3096551471 cites W2048915076 @default.
• W3096551471 cites W2052313189 @default.
• W3096551471 cites W2078889151 @default.
• W3096551471 cites W2079236205 @default.
• W3096551471 cites W2081604319 @default.
• W3096551471 cites W2116714467 @default.
• W3096551471 cites W2125392114 @default.
• W3096551471 cites W2151102178 @default.
• W3096551471 cites W2157904413 @default.
• W3096551471 cites W2161952636 @default.
• W3096551471 cites W2172098894 @default.
• W3096551471 cites W2252694649 @default.
• W3096551471 cites W2284613985 @default.
• W3096551471 cites W2333744465 @default.
• W3096551471 cites W2348647453 @default.
• W3096551471 cites W2543999136 @default.
• W3096551471 cites W2572115232 @default.
• W3096551471 cites W2610203641 @default.
• W3096551471 cites W2755420867 @default.
• W3096551471 cites W2758073366 @default.
• W3096551471 cites W2772630784 @default.
• W3096551471 cites W2782012781 @default.
• W3096551471 cites W2783888432 @default.
• W3096551471 cites W2794106846 @default.
• W3096551471 cites W2883278443 @default.
• W3096551471 cites W2886397848 @default.
• W3096551471 cites W2887744195 @default.
• W3096551471 cites W2891918534 @default.
• W3096551471 cites W2903148255 @default.
• W3096551471 cites W2908637567 @default.
• W3096551471 cites W2913004370 @default.
• W3096551471 cites W2922606230 @default.
• W3096551471 cites W2946101639 @default.
• W3096551471 cites W2951118172 @default.
• W3096551471 cites W2983485988 @default.
• W3096551471 cites W4256475235 @default.
• W3096551471 cites W45977844 @default.
• W3096551471 doi "https://doi.org/10.1007/s43188-020-00066-x" @default.
• W3096551471 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8249546" @default.
• W3096551471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34295795" @default.
• W3096551471 hasPublicationYear "2020" @default.
• W3096551471 type Work @default.
• W3096551471 sameAs 3096551471 @default.
• W3096551471 citedByCount "2" @default.
• W3096551471 countsByYear W30965514712022 @default.
• W3096551471 countsByYear W30965514712023 @default.
• W3096551471 crossrefType "journal-article" @default.
• W3096551471 hasAuthorship W3096551471A5008781978 @default.
• W3096551471 hasAuthorship W3096551471A5014426469 @default.
• W3096551471 hasAuthorship W3096551471A5028544162 @default.
• W3096551471 hasAuthorship W3096551471A5039369542 @default.
• W3096551471 hasAuthorship W3096551471A5051741661 @default.
• W3096551471 hasAuthorship W3096551471A5054156788 @default.
• W3096551471 hasAuthorship W3096551471A5056174606 @default.
• W3096551471 hasAuthorship W3096551471A5064948920 @default.
• W3096551471 hasAuthorship W3096551471A5072241532 @default.
• W3096551471 hasAuthorship W3096551471A5072762941 @default.
• W3096551471 hasAuthorship W3096551471A5072834025 @default.
• W3096551471 hasAuthorship W3096551471A5086745623 @default.
• W3096551471 hasBestOaLocation W30965514712 @default.
• W3096551471 hasConcept C126322002 @default.
• W3096551471 hasConcept C134018914 @default.
• W3096551471 hasConcept C142724271 @default.
• W3096551471 hasConcept C170493617 @default.

• next