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- W3096606141 endingPage "578" @default.
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- W3096606141 abstract "Biosensors are analytical tools with a great application in healthcare, food quality control, and environmental monitoring. They are of considerable interest to be designed by using cost-effective and efficient approaches. Designing biosensors with improved functionality or application in new target detection has been converted to a fast-growing field of biomedicine and biotechnology branches. Experimental efforts have led to valuable successes in the field of biosensor design; however, some deficiencies restrict their utilization for this purpose. Computational design of biosensors is introduced as a promising key to eliminate the gap. A set of reliable structure prediction of the biosensor segments, their stability, and accurate descriptors of molecular interactions are required to computationally design biosensors. In this review, we provide a comprehensive insight into the progress of computational methods to guide the design and development of biosensors, including molecular dynamics simulation, quantum mechanics calculations, molecular docking, virtual screening, and a combination of them as the hybrid methodologies. By relying on the recent advances in the computational methods, an opportunity emerged for them to be complementary or an alternative to the experimental methods in the field of biosensor design." @default.
- W3096606141 created "2020-11-09" @default.
- W3096606141 creator A5000664644 @default.
- W3096606141 creator A5020797123 @default.
- W3096606141 creator A5038382890 @default.
- W3096606141 creator A5045556796 @default.
- W3096606141 creator A5054755615 @default.
- W3096606141 date "2020-11-17" @default.
- W3096606141 modified "2023-09-24" @default.
- W3096606141 title "Recent advances in computational methods for biosensor design" @default.
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