FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3096648506> ?p ?o ?g. }

• W3096648506 abstract "Objectives Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer health benefits to the host. Probiotics are currently being recommended and considered for many medical conditions. The Asia-Pacific region contributes to more than 40% of the global industry. Quality of commercial probiotics remains a challenge globally and has been a major concern in various countries in Europe, South Africa, Taiwan, India, Pakistan, and the USA. Research from these countries indicate that the contents do not correspond to the label information in terms of identity, viability, number of microorganisms or purity. The objective of this study is to assess the commercial probiotic bacterial contents and their label accuracy in India. No previous research has been done in this area in India, on commercial probiotics that are sold as pharmaceuticals. Methods A random selection of the most prescribed probiotics for various clinical indications were chosen with a minimum shelf life of 12 months. The probiotics were single and multiple strains and these were evaluated by culture, viable plate count, DNA isolation and targeted metagenomics. Our study is the first step in scrutinizing probiotics in terms of quality and quantity analysis which are used across various age groups for multiple indications. Results Out of the 20 chosen probiotics eight products were single strain and 12 products were multiple strains. These probiotics showed very poor correlation between the declared contents on the pack and lab values in viable cell count colonies, the genus and species strain identification, presence of contaminants and these were confirmed with 16s RNA and next generation sequencing. Conclusion Poor correlation in the quality and quantity of probiotics proves that the label claim and actual claim of these drugs show exceptionally poor correlation and raises safety concerns in clinical use, especially in vulnerable age groups such as neonates, children and the elderly. Our study shows that policing of these probiotics is essential in protecting these patients who are at risk and ensuring quality control and helping clinicians making the right choice." @default.
• W3096648506 created "2020-11-09" @default.
• W3096648506 creator A5021733468 @default.
• W3096648506 creator A5032437374 @default.
• W3096648506 creator A5089393967 @default.
• W3096648506 date "2020-11-05" @default.
• W3096648506 modified "2023-10-14" @default.
• W3096648506 title "Composition and Laboratory Correlation of Commercial Probiotics in India" @default.
• W3096648506 cites W1565458887 @default.
• W3096648506 cites W1980953021 @default.
• W3096648506 cites W1988185577 @default.
• W3096648506 cites W2007807635 @default.
• W3096648506 cites W2027955126 @default.
• W3096648506 cites W2030537885 @default.
• W3096648506 cites W2040280445 @default.
• W3096648506 cites W2052237626 @default.
• W3096648506 cites W2065320423 @default.
• W3096648506 cites W2094100452 @default.
• W3096648506 cites W2096933974 @default.
• W3096648506 cites W2130791789 @default.
• W3096648506 cites W2146734947 @default.
• W3096648506 cites W2149074973 @default.
• W3096648506 cites W2168086802 @default.
• W3096648506 cites W2607382916 @default.
• W3096648506 cites W2740851935 @default.
• W3096648506 cites W2741572010 @default.
• W3096648506 cites W2900428732 @default.
• W3096648506 cites W4300425742 @default.
• W3096648506 cites W4302482453 @default.
• W3096648506 cites W99599213 @default.
• W3096648506 doi "https://doi.org/10.7759/cureus.11334" @default.
• W3096648506 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7647373" @default.
• W3096648506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33173652" @default.
• W3096648506 hasPublicationYear "2020" @default.
• W3096648506 type Work @default.
• W3096648506 sameAs 3096648506 @default.
• W3096648506 citedByCount "11" @default.
• W3096648506 countsByYear W30966485062021 @default.
• W3096648506 countsByYear W30966485062022 @default.
• W3096648506 countsByYear W30966485062023 @default.
• W3096648506 crossrefType "journal-article" @default.
• W3096648506 hasAuthorship W3096648506A5021733468 @default.
• W3096648506 hasAuthorship W3096648506A5032437374 @default.
• W3096648506 hasAuthorship W3096648506A5089393967 @default.
• W3096648506 hasBestOaLocation W30966485061 @default.
• W3096648506 hasConcept C104317684 @default.
• W3096648506 hasConcept C150903083 @default.
• W3096648506 hasConcept C15151743 @default.
• W3096648506 hasConcept C175605896 @default.
• W3096648506 hasConcept C2775941552 @default.
• W3096648506 hasConcept C2780255968 @default.
• W3096648506 hasConcept C523546767 @default.
• W3096648506 hasConcept C54355233 @default.
• W3096648506 hasConcept C55493867 @default.
• W3096648506 hasConcept C71924100 @default.
• W3096648506 hasConcept C86803240 @default.
• W3096648506 hasConcept C89423630 @default.
• W3096648506 hasConceptScore W3096648506C104317684 @default.
• W3096648506 hasConceptScore W3096648506C150903083 @default.
• W3096648506 hasConceptScore W3096648506C15151743 @default.
• W3096648506 hasConceptScore W3096648506C175605896 @default.
• W3096648506 hasConceptScore W3096648506C2775941552 @default.
• W3096648506 hasConceptScore W3096648506C2780255968 @default.
• W3096648506 hasConceptScore W3096648506C523546767 @default.
• W3096648506 hasConceptScore W3096648506C54355233 @default.
• W3096648506 hasConceptScore W3096648506C55493867 @default.
• W3096648506 hasConceptScore W3096648506C71924100 @default.
• W3096648506 hasConceptScore W3096648506C86803240 @default.
• W3096648506 hasConceptScore W3096648506C89423630 @default.
• W3096648506 hasLocation W30966485061 @default.
• W3096648506 hasLocation W30966485062 @default.
• W3096648506 hasLocation W30966485063 @default.
• W3096648506 hasOpenAccess W3096648506 @default.
• W3096648506 hasPrimaryLocation W30966485061 @default.
• W3096648506 hasRelatedWork W2093442073 @default.
• W3096648506 hasRelatedWork W2298707151 @default.
• W3096648506 hasRelatedWork W2323419124 @default.
• W3096648506 hasRelatedWork W2472011611 @default.
• W3096648506 hasRelatedWork W2753518258 @default.
• W3096648506 hasRelatedWork W3165107523 @default.
• W3096648506 hasRelatedWork W3215714629 @default.
• W3096648506 hasRelatedWork W4229332721 @default.
• W3096648506 hasRelatedWork W4292451903 @default.
• W3096648506 hasRelatedWork W87314493 @default.
• W3096648506 isParatext "false" @default.
• W3096648506 isRetracted "false" @default.
• W3096648506 magId "3096648506" @default.
• W3096648506 workType "article" @default.