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• W3096772873 abstract "This study investigated the acute effects of including 30‐second sprints during prolonged low‐intensity cycling on muscular and hormonal responses and recovery in elite cyclists. Twelve male cyclists (VO 2max , 73.4 ± 4.0 mL/kg/min) completed a randomized crossover protocol, wherein 4 hours of cycling at 50% of VO 2max were performed with and without inclusion of three sets of 3 × 30 seconds maximal sprints ( E&S vs E, work‐matched). Muscle biopsies (m. vastus lateralis) and blood were sampled at Pre, immediately after (Post) and 3 hours after (3 h) finalizing sessions. E&S led to greater increases in mRNA levels compared with E for markers of fat metabolism (PDK4, Δ‐Log2 fold change between E&S and E ± 95%CI Post; 2.1 ± 0.9, Δ3h; 1.3 ± 0.7) and angiogenesis (VEGFA, Δ3h; 0.3 ± 0.3), and greater changes in markers of muscle protein turnover (myostatin, ΔPost; −1.4 ± 1.2, Δ3h; −1.3 ± 1.3; MuRF1, ΔPost; 1.5 ± 1.2, all P < .05). E&S showed decreased mRNA levels for markers of ion transport at 3h (Na + ‐K + α1; −0.6 ± 0.6, CLC1; −1.0 ± 0.8 and NHE1; −0.3 ± 0.2, all P < .05) and blunted responses for a marker of mitochondrial biogenesis (PGC‐1α, Post; −0.3 ± 0.3, 3h; −0.4 ± 0.3, P < .05) compared with E E&S and E showed similar endocrine responses, with exceptions of GH and SHBG, where E&S displayed lower responses at Post (GH; −4.1 ± 3.2 μg/L, SHBG; −2.2 ± 1.9 nmol/L, P < .05). Both E&S and E demonstrated complete recovery in isokinetic knee extension torque 24 hours after exercise. In conclusion, we demonstrate E&S to be an effective exercise protocol for elite cyclists, which potentially leads to beneficial adaptations in skeletal muscle without impairing muscle recovery 24 hours after exercise." @default.
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• W3096772873 date "2020-11-07" @default.
• W3096772873 modified "2023-09-24" @default.
• W3096772873 title "Effects of including sprints during prolonged cycling on hormonal and muscular responses and recovery in elite cyclists" @default.
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• W3096772873 doi "https://doi.org/10.1111/sms.13865" @default.
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